Used 2021 Lexus RX for Sale Nationwide

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2022 Lexus RX

350 AWD

23,430 miles

$38,899

Good Deal

Wappingers Falls, NY

1 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black (Caviar)
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: White (Parchment)
Transmission:: 8-Speed Automatic
Mileage:: 23,430
Stock number:: T14791
VIN:: 2T2HZMDA6NC319723

2020 Lexus RX

350 F Sport Performance AWD

86,117 miles

$31,998

Good Deal

Stockton, CA

1 mi away

Year:: 2020
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Red
Transmission:: Automatic
Mileage:: 86,117
Stock number:: 28244253
VIN:: 2T2YZMDA3LC235422

2021 Lexus RX

350 FWD

83,149 miles

$27,995

Great Deal

Trenton, MO

1 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Gray
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Ash
Transmission:: 8-Speed Automatic
Mileage:: 83,149
Stock number:: P1605A
VIN:: 2T2HZMAA9MC204388

2022 Lexus RX

350 AWD

80,607 miles

$30,373

Good Deal

Stroudsburg, PA

1 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black (Caviar - 223)
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Black - 24
Transmission:: Automatic
Mileage:: 80,607
Stock number:: F51825
VIN:: 2T2HZMDA9NC351825

2022 Lexus RX

350 FWD

31,770 miles

$43,998

Fair Deal

Leesburg, GA

1 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Eminent White Pearl
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Birch
Transmission:: 8-Speed Automatic
Mileage:: 31,770
Stock number:: 257591
VIN:: 2T2HZMAA5NC257591

2022 Lexus RX

350L AWD

39,814 miles

$36,646

Great Deal

Langhorne, PA

1 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 290 hp 3.5L V6
Exterior color:: Black (Caviar 223)
Combined gas mileage:: 21 MPG
Fuel type:: Gasoline
Interior color:: Black 23
Transmission:: Automatic
Mileage:: 39,814
Stock number:: 131836A
VIN:: JTJHZKFA7N2036880

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2020 Lexus RX

350 F Sport AWD

86,038 miles

$28,995

Great Deal

Knoxville, TN

1 mi away

Year:: 2020
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: White
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 86,038
Stock number:: LC227260
VIN:: 2T2SZMDAXLC227260

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2021 Lexus RX

350L AWD

74,958 miles

$32,995

Good Deal

Vandalia, OH

1 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 290 hp 3.5L V6
Exterior color:: Black (Obsidian)
Combined gas mileage:: 21 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 8-Speed Automatic
Mileage:: 74,958
Stock number:: N26T130A
VIN:: JTJHZKFA9M2028424

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2021 Lexus RX

350 FWD

92,805 miles

$27,244

Great Deal

Jonesboro, AR

1 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Brown (Tan)
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: White (Parchment)
Transmission:: 8-Speed Automatic
Mileage:: 92,805
Stock number:: HJ1822A
VIN:: 2T2AZMAA5MC200968

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2021 Lexus RX

350 FWD

103,298 miles

$25,500

Great Deal

Davenport, FL

1 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Silver
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Birch
Transmission:: 8-Speed Automatic
Mileage:: 103,298
Stock number:: U774780A
VIN:: 2T2HZMAA6MC190711

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2021 Lexus RX

350 F Sport AWD

71,827 miles

$33,999

Good Deal

Barrington, IL

1 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black (Obsidian)
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Circuit Red
Transmission:: 8-Speed Automatic
Mileage:: 71,827
Stock number:: PMR6373
VIN:: 2T2SZMDA3MC271506

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2022 Lexus RX

350 AWD

40,230 miles

$35,900

Good Deal

Shrewsbury, NJ

1 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Cloudburst Gray
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 8-Speed Automatic
Mileage:: 40,230
Stock number:: RS195126Q
VIN:: 2T2HZMDA3NC344384

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2020 Lexus RX

350 F Sport AWD

97,440 miles

$28,997

Good Deal

Raleigh, NC

1 mi away

Year:: 2020
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Gray
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 97,440
Stock number:: LC236348
VIN:: 2T2SZMDA3LC236348

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2021 Lexus RX

350 AWD

62,100 miles

$34,995

Good Deal

Albany, OR

1 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Atomic Silver
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 8-Speed Automatic
Mileage:: 62,100
Stock number:: H26036A
VIN:: JTJHZMDA8M2050865

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2020 Lexus RX

350 F Sport Performance AWD

64,713 miles

$32,900

Good Deal

Weymouth, MA

1 mi away

Year:: 2020
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: White
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Red
Transmission:: Automatic
Mileage:: 64,713
Stock number:: 14491
VIN:: 2T2YZMDA6LC231512

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2021 Lexus RX

350 FWD

53,850 miles

$32,476

Great Deal

Lisle, IL

1 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Brown (Moonbeam Beige Metallic)
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 8-Speed Automatic
Mileage:: 53,850
Stock number:: VA3172B
VIN:: 2T2AZMAA5MC202073

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2022 Lexus RX

350 FWD

48,215 miles

$34,841

Great Deal

Birmingham, AL

1 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Matador Red Mica
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Birch
Transmission:: 8-Speed Automatic
Mileage:: 48,215
Stock number:: P9943
VIN:: 2T2AZMAA4NC227984

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2022 Lexus RX

350 FWD

103,210 miles

$28,677

Great Deal

Certified Pre-Owned

Temecula, CA

1 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Atomic Silver
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 8-Speed Automatic
Mileage:: 103,210
Stock number:: T03705L
VIN:: 2T2AZMAA4NC253808

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2022 Lexus RX

350 AWD

79,284 miles

$27,995

Great Deal

Bronx, NY

1 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 8-Speed Automatic
Mileage:: 79,284
Stock number:: 30188
VIN:: 2T2HZMDAXNC354829

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2020 Lexus RX

350 F Sport Performance AWD

76,353 miles

$32,495

Good Deal

Jasper, AL

1 mi away

Year:: 2020
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black (Caviar)
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Circuit Red
Transmission:: 8-Speed Automatic
Mileage:: 76,353
Stock number:: G26136B
VIN:: 2T2YZMDA1LC237685

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2021 Lexus RX

350 FWD

59,421 miles

$32,993

Good Deal

San Juan, TX

1 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Transmission:: Automatic
Mileage:: 59,421
Stock number:: RR190725
VIN:: 2T2HZMAA6MC190725

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2022 Lexus RX

350 FWD

62,210 miles

$32,499

Good Deal

Signal Hill, CA

1 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Gray
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 62,210
Stock number:: 25581T
VIN:: 2T2HZMAA2NC245771

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2020 Lexus RX

350 F Sport Performance AWD

47,825 miles

$36,995

Good Deal

Parker, CO

1 mi away

Year:: 2020
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black (Caviar)
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 47,825
Stock number:: T212410
VIN:: 2T2YZMDA2LC212410

Overview

Reviews

FAQs

CarGurus Analysis: 2021 Lexus RX

Summary

With 1,829 currently listed for sale on CarGurus and an average price of $35,773.40, 32.3% of 2021 Lexus RXs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.7 / 5 stars and CarGurus experts gave it an 7.8 / 10.
79% of 2021 RX models on CarGurus are accident free.
The 2021 Lexus RX combined luxurious comfort with reliability, featuring upgraded safety technology and a smooth ride, although it had some limitations in performance and technology usability.

Why it stands out

The 2021 Lexus RX distinguished itself as a luxury SUV that emphasized comfort and reliability, making it an appealing choice for buyers seeking both style and practicality. It featured an excellent ride quality and offered great value for money, ensuring a pleasant driving experience. Additionally, the introduction of new standard safety systems enhanced its appeal by prioritizing passenger protection.

Other model years to consider

2020 Lexus RX: This year offers $33,379.27 average price, 33% good/great deals, 4.8/5 user rating, 8.2/10 expert rating, 1,269 listings.
2023 Lexus RX: This year offers $47,405.06 average price, 37% good/great deals, 4.6/5 user rating, 7.2/10 expert rating, 3,056 listings.
2022 Lexus RX: This year offers $40,414.56 average price, 36% good/great deals, 4.6/5 user rating, 7.3/10 expert rating, 2,526 listings.

This analysis is based on CarGurus' proprietary market data from December 16, 2025, CarGurus experts' opinions, and generative AI.

4.8 Overall rating

(26 reviews)

Archie C

5.0

Reviewed a 2021 Lexus RX on Oct 13, 2024

Very reliable stylish looking drives well. Good suspension. Fun to drive

Dan F

5.0

Reviewed a 2021 Lexus RX on Mar 26, 2024

Condition of the vehicle was 10/10. Interior was detailed extremely well. Mechanically it all checked out as well. Only issue was since it is a Canadian vehicle the digital climate controls appear to be stuck in Celsius. Could be a troubleshoot to resolve it but other than that perfect vehicle.

Haidar A

5.0

Reviewed a 2021 Lexus 350L AWD on Apr 25, 2024

The car is perfect if only the brakes were as responsive of a German car.

Ann W

5.0

Reviewed a 2021 Lexus RX on Feb 22, 2023

This car is beautiful and drives so smooth.

Anonymous

5.0

Reviewed a 2021 Lexus RX on Nov 04, 2023

Perfect for me and my family (except for the Parchment interior that my kids will probably ruin) but I love it!so I will do everything to keep it clean.. this car is superior family luxury! Have kid? Needs spacious trunk and seating but doesnt want it looking huge and bulky outside? Needs reliability? Need quality? Need LUXURY? look no further the RX 350 IS THE CAR FOR YOU!

2021 Lexus RX FAQs

How much does the 2021 Lexus RX cost?

The average 2021 Lexus RX costs about $35,553.55. The average price has decreased by -3.5% since last year. The 1500 for sale on CarGurus range from $21,585 to $410,000 in price.

Is the 2021 Lexus RX a good car?

CarGurus experts gave the 2021 Lexus RX an overall rating of 7.8/10 and 2021 Lexus RX owners have rated the vehicle a 4.7/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2021 Lexus RX vehicles have no reported accidents or damage?

1132 out of 1500 for sale have no reported accidents or damage.

Is the 2021 Lexus RX safe?

CarGurus experts gave the 2021 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2021 Lexus RX?

Depending on the engine and options, the 2021 Lexus RX gets between 21 and 23 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

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