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Used 2021 Lexus RX for Sale near Chicago, IL

125 results
Chicago, IL
2022 Lexus RX 350 F Sport Handling AWD Advantage Toyota of River Oaks

2022 Lexus RX

350 F Sport Handling AWD

52,771 miles

$38,482

Good Deal
Calumet City, IL
19 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nightfall Mica
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
52,771
Stock number:
P6909
VIN:
2T2YZMDA3NC352338

Sponsored

2022 Lexus RX 350L AWD

2022 Lexus RX

350L AWD

58,760 miles

$36,990

Good Deal
Bartlett, IL
32 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
58,760
Stock number:
G2182A
VIN:
JTJHZKFA3N2034995

Sponsored

2022 Lexus RX 350 F Sport AWD

2022 Lexus RX

350 F Sport AWD

23,136 miles

$43,999

Fair Deal
Morton Grove, IL
15 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
23,136
Stock number:
PG6947
VIN:
2T2SZMDA5NC341671

Sponsored

2022 Lexus RX 350 F Sport Handling AWD

2022 Lexus RX

350 F Sport Handling AWD

55,745 miles

$38,751

Good Deal
Schaumburg, IL
25 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Cloudburst Gray
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
55,745
Stock number:
P1320A
VIN:
2T2YZMDA4NC336049

2022 Lexus RX 350 F Sport AWD

2022 Lexus RX

350 F Sport AWD

32,729 miles

$45,097

Fair Deal
Store transfer to Oak Lawn, IL
939 mi away • Price includes $1,099 shipping Price includes $1,099 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Red
Transmission:
Automatic
Mileage:
32,729
Stock number:
27560644
VIN:
2T2SZMDA2NC352496

2022 Lexus RX 350 AWD

2022 Lexus RX

350 AWD

27,636 miles

$43,797

Good Deal
Store transfer to Oak Lawn, IL
901 mi away • Price includes $799 shipping Price includes $799 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
27,636
Stock number:
27650449
VIN:
2T2JZMDA3NC357055

Preparing for a close up...

Photos coming soon

2020 Lexus RX

350 FWD

74,489 miles

$28,852

Great Deal
Crown Point, IN
30 mi away
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
74,489
Stock number:
JP3219A
VIN:
2T2HZMAAXLC162859

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350L AWD

103,146 miles

$28,995

Good Deal
Burbank, IL
13 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
Automatic
Mileage:
103,146
Stock number:
B32418
VIN:
JTJHZKFA7M2033783

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 F Sport Handling AWD

44,128 miles

$41,400

Good Deal
Morton Grove, IL
15 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
Automatic
Mileage:
44,128
Stock number:
PG6859
VIN:
2T2YZMDA5NC364054

Preparing for a close up...

Photos coming soon

2020 Lexus RX

350 FWD

77,304 miles

$29,688

Good Deal
Highland Park, IL
21 mi away
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
8-Speed Automatic
Mileage:
77,304
Stock number:
K52740A
VIN:
2T2HZMAAXLC169567

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 F Sport Handling AWD

52,771 miles

$38,482

Good Deal
Calumet City, IL
19 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nightfall Mica
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
52,771
Stock number:
P6909
VIN:
2T2YZMDA3NC352338

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 AWD

31,620 miles

$40,697

Good Deal
Store transfer to Oak Lawn, IL
820 mi away • Price includes $699 shipping Price includes $699 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
31,620
Stock number:
28137915
VIN:
2T2HZMDA3NC322045

Preparing for a close up...

Photos coming soon

2020 Lexus RX

350 AWD

44,946 miles

$34,500

Good Deal
Mt. Prospect, IL
21 mi away
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
Automatic
Mileage:
44,946
Stock number:
243594
VIN:
2T2HZMDA6LC243594

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350L AWD

52,081 miles

$38,520

Good Deal
Orland Park, IL
24 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
52,081
Stock number:
9302X
VIN:
JTJHZKFA7N2038502

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350L AWD

46,884 miles

$39,627

Good Deal
Elk Grove Village, IL
21 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Eminent White Pearl
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
46,884
Stock number:
NC3577
VIN:
JTJHZKFA0N2042164

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 F Sport AWD

23,136 miles

$43,999

Fair Deal
Morton Grove, IL
15 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
23,136
Stock number:
PG6947
VIN:
2T2SZMDA5NC341671

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350L FWD

45,499 miles

$37,347

Good Deal
Store transfer to Oak Lawn, IL
700 mi away • Price includes $349 shipping Price includes $349 shipping
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
45,499
Stock number:
28031336
VIN:
JTJHZKEA0M2021234

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 AWD

73,756 miles

$33,588

Fair Deal
Palatine, IL
27 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Ultra White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
73,756
Stock number:
K19178A
VIN:
2T2HZMDA1MC271806

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 AWD

85,673 miles

$31,410

Good Deal
Westmont, IL
18 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nebula Gray Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
8-Speed Automatic
Mileage:
85,673
Stock number:
E1034A
VIN:
2T2HZMDA0MC282084

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 AWD

88,443 miles

$33,897

Fair Deal
Crystal Lake, IL
43 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Eminent White Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black/Birch
Transmission:
Automatic
Mileage:
88,443
Stock number:
P00966
VIN:
2T2HZMDA4NC322989

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2021
  5. / Illinois
  6. / Chicago
Overview
Reviews
FAQs

CarGurus Analysis: 2021 Lexus RX

Picture of 2021 Lexus RX

Summary

  • With 1,840 currently listed for sale on CarGurus and an average price of $35,808.30, 33.5% of 2021 Lexus RXs for sale on CarGurus are rated as good or great deals.
  • Favorably reviewed: Owners rated the 2021 Lexus RX 4.7 / 5 stars and CarGurus experts gave it an 7.8 / 10.
  • 79.2% of 2021 RX models on CarGurus are accident free.
  • The 2021 Lexus RX combined luxury and reliability with a comfortable ride and notable tech upgrades, making it a solid choice in the midsize SUV segment.

Why it stands out

The 2021 Lexus RX stood out in the luxury SUV segment due to its exceptional ride quality and comfortable interior, making it a pleasant choice for both daily commutes and long journeys. It offered a strong reputation for reliability, reflecting Lexus' commitment to quality, while also incorporating new standard safety features that enhanced its appeal. Despite some challenges with performance and technology usability, it provided excellent value for money in the midsize SUV market.

Other model years to consider

  • 2020 Lexus RX: This year offers $33,383.04 average price, 32% good/great deals, 4.8/5 user rating, 8.2/10 expert rating, 1,248 listings.
  • 2023 Lexus RX: This year offers $47,685.72 average price, 36% good/great deals, 4.6/5 user rating, 7.2/10 expert rating, 3,126 listings.
  • 2022 Lexus RX: This year offers $40,523.25 average price, 36% good/great deals, 4.6/5 user rating, 7.3/10 expert rating, 2,583 listings.

This analysis is based on CarGurus' proprietary market data from December 3, 2025, CarGurus experts' opinions, and generative AI.

4.8 Overall rating

(26 reviews)
Archie C
5.0
Reviewed a 2021 Lexus RX on Oct 13, 2024

Very reliable stylish looking drives well. Good suspension. Fun to drive

Dan F
5.0
Reviewed a 2021 Lexus RX on Mar 26, 2024

Condition of the vehicle was 10/10. Interior was detailed extremely well. Mechanically it all checked out as well. Only issue was since it is a Canadian vehicle the digital climate controls appear to be stuck in Celsius. Could be a troubleshoot to resolve it but other than that perfect vehicle.

Haidar A
5.0
Reviewed a 2021 Lexus 350L AWD on Apr 25, 2024

The car is perfect if only the brakes were as responsive of a German car.

Ann W
5.0
Reviewed a 2021 Lexus RX on Feb 22, 2023

This car is beautiful and drives so smooth.

Anonymous
5.0
Reviewed a 2021 Lexus RX on Nov 04, 2023

Perfect for me and my family (except for the Parchment interior that my kids will probably ruin) but I love it!so I will do everything to keep it clean.. this car is superior family luxury! Have kid? Needs spacious trunk and seating but doesnt want it looking huge and bulky outside? Needs reliability? Need quality? Need LUXURY? look no further the RX 350 IS THE CAR FOR YOU!

2021 Lexus RX FAQs

How much does the 2021 Lexus RX cost in Chicago, IL?

The average 2021 Lexus RX costs about $35,747.79. The average price has decreased by -5.4% since last year. The 125 for sale near Chicago, IL on CarGurus, range from $25,536 to $48,995 in price.

Is the 2021 Lexus RX a good car?

CarGurus experts gave the 2021 Lexus RX an overall rating of 7.8/10 and 2021 Lexus RX owners have rated the vehicle a 4.7/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2021 Lexus RX vehicles in Chicago, IL have no reported accidents or damage?

125 out of 125 for sale near Chicago, IL have no reported accidents or damage.

Is the 2021 Lexus RX safe?

CarGurus experts gave the 2021 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2021 Lexus RX?

Depending on the engine and options, the 2021 Lexus RX gets between 21 and 23 MPG (or MPGe).

What fuel types are available?

Gasoline engines are available.

  • 2024 Lexus RX in Chicago IL

  • 2023 Lexus RX in Chicago IL

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