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Used 2021 Lexus RX for Sale near Ohio

110 results
Cincinnati, OH
2022 Lexus RX 350 FWD

2022 Lexus RX

350 FWD

25,432 miles

$37,665

Good Deal
Cincinnati, OH
10 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Red
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
25,432
Stock number:
62117349A
VIN:
2T2HZMAA4NC223836

Sponsored

2020 Lexus RX 350 AWD

2020 Lexus RX

350 AWD

80,394 miles

$28,852

Good Deal
Cincinnati, OH
18 mi away
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Ultra White
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
8-Speed Automatic Overdrive
Mileage:
80,394
Stock number:
LC252563
VIN:
2T2HZMDA7LC252563

Sponsored

2022 Lexus RX 350L AWD

2022 Lexus RX

350L AWD

33,965 miles

$42,498

Fair Deal
West Chester, OH
17 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
33,965
Stock number:
TN2040837
VIN:
JTJHZKFA4N2040837

Sponsored

2022 Lexus RX 350 FWD

2022 Lexus RX

350 FWD

25,432 miles

$37,665

Good Deal
Cincinnati, OH
10 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Red
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
25,432
Stock number:
62117349A
VIN:
2T2HZMAA4NC223836

2021 Lexus RX 350 AWD

2021 Lexus RX

350 AWD

73,928 miles

$28,998

Great Deal
Dayton, OH
50 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Obsidian)
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
73,928
Stock number:
P9101
VIN:
2T2HZMDA3MC266218

2022 Lexus RX 350L AWD

2022 Lexus RX

350L AWD

38,788 miles

$41,500

Fair Deal
Cincinnati, OH
18 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
38,788
Stock number:
N2039656
VIN:
JTJHZKFA6N2039656

Preparing for a close up...

Photos coming soon

2020 Lexus RX

350 FWD

50,281 miles

$36,497

Fair Deal
Store transfer to Cincinnati, OH
1,324 mi away • Price includes $1,499 shipping Price includes $1,499 shipping
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Brown (TAN)
Transmission:
Automatic
Mileage:
50,281
Stock number:
28175527
VIN:
2T2HZMAA6LC174541

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 F Sport Handling AWD

54,484 miles

$41,397

Good Deal
Store transfer to Cincinnati, OH
395 mi away • Price includes $399 shipping Price includes $399 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
54,484
Stock number:
27190672
VIN:
2T2YZMDA1NC321556

Preparing for a close up...

Photos coming soon

2020 Lexus RX

350 AWD

70,763 miles

$29,498

Good Deal
Cincinnati, OH
18 mi away
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Ultra White
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic Overdrive
Mileage:
70,763
Stock number:
LC232839
VIN:
2T2HZMDAXLC232839

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

30,047 miles

$38,497

Good Deal
Store transfer to Cincinnati, OH
1,333 mi away • Price includes $1,499 shipping Price includes $1,499 shipping
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Brown (Tan)
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Brown (TAN)
Transmission:
Automatic
Mileage:
30,047
Stock number:
27402680
VIN:
2T2HZMAA8MC188376

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 AWD

56,452 miles

$34,898

Good Deal
Cincinnati, OH
18 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
56,452
Stock number:
NC330911
VIN:
2T2HZMDA7NC330911

Preparing for a close up...

Photos coming soon

2020 Lexus RX

350 AWD

80,394 miles

$28,852

Good Deal
Cincinnati, OH
18 mi away
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Ultra White
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
8-Speed Automatic Overdrive
Mileage:
80,394
Stock number:
LC252563
VIN:
2T2HZMDA7LC252563

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 AWD

69,716 miles

$31,780

Good Deal
Centerville, OH
40 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nightfall Mica
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
69,716
Stock number:
AMC289278
VIN:
2T2HZMDA4MC289278

Preparing for a close up...

Photos coming soon

2020 Lexus RX

350 AWD

70,763 miles

$29,498

Good Deal
Cincinnati, OH
18 mi away
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Ultra White
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic Overdrive
Mileage:
70,763
Stock number:
LC232839
VIN:
2T2HZMDAXLC232839

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2021
  5. / Ohio
Overview
Reviews
FAQs

CarGurus Analysis: 2021 Lexus RX

Picture of 2021 Lexus RX

Summary

  • With 1,840 currently listed for sale on CarGurus and an average price of $35,808.30, 33.5% of 2021 Lexus RXs for sale on CarGurus are rated as good or great deals.
  • Favorably reviewed: Owners rated the 2021 Lexus RX 4.7 / 5 stars and CarGurus experts gave it an 7.8 / 10.
  • 79.2% of 2021 RX models on CarGurus are accident free.
  • The 2021 Lexus RX combined luxury and reliability with a comfortable ride and notable tech upgrades, making it a solid choice in the midsize SUV segment.

Why it stands out

The 2021 Lexus RX stood out in the luxury SUV segment due to its exceptional ride quality and comfortable interior, making it a pleasant choice for both daily commutes and long journeys. It offered a strong reputation for reliability, reflecting Lexus' commitment to quality, while also incorporating new standard safety features that enhanced its appeal. Despite some challenges with performance and technology usability, it provided excellent value for money in the midsize SUV market.

Other model years to consider

  • 2020 Lexus RX: This year offers $33,383.04 average price, 32% good/great deals, 4.8/5 user rating, 8.2/10 expert rating, 1,248 listings.
  • 2023 Lexus RX: This year offers $47,685.72 average price, 36% good/great deals, 4.6/5 user rating, 7.2/10 expert rating, 3,126 listings.
  • 2022 Lexus RX: This year offers $40,523.25 average price, 36% good/great deals, 4.6/5 user rating, 7.3/10 expert rating, 2,583 listings.

This analysis is based on CarGurus' proprietary market data from December 3, 2025, CarGurus experts' opinions, and generative AI.

4.8 Overall rating

(26 reviews)
Archie C
5.0
Reviewed a 2021 Lexus RX on Oct 13, 2024

Very reliable stylish looking drives well. Good suspension. Fun to drive

Dan F
5.0
Reviewed a 2021 Lexus RX on Mar 26, 2024

Condition of the vehicle was 10/10. Interior was detailed extremely well. Mechanically it all checked out as well. Only issue was since it is a Canadian vehicle the digital climate controls appear to be stuck in Celsius. Could be a troubleshoot to resolve it but other than that perfect vehicle.

Haidar A
5.0
Reviewed a 2021 Lexus 350L AWD on Apr 25, 2024

The car is perfect if only the brakes were as responsive of a German car.

Ann W
5.0
Reviewed a 2021 Lexus RX on Feb 22, 2023

This car is beautiful and drives so smooth.

Anonymous
5.0
Reviewed a 2021 Lexus RX on Nov 04, 2023

Perfect for me and my family (except for the Parchment interior that my kids will probably ruin) but I love it!so I will do everything to keep it clean.. this car is superior family luxury! Have kid? Needs spacious trunk and seating but doesnt want it looking huge and bulky outside? Needs reliability? Need quality? Need LUXURY? look no further the RX 350 IS THE CAR FOR YOU!

2021 Lexus RX FAQs

How much does the 2021 Lexus RX cost in Ohio?

The average 2021 Lexus RX costs about $35,772.63. The average price has decreased by -5.4% since last year. The 110 for sale near Ohio on CarGurus, range from $25,814 to $46,750 in price.

Is the 2021 Lexus RX a good car?

CarGurus experts gave the 2021 Lexus RX an overall rating of 7.8/10 and 2021 Lexus RX owners have rated the vehicle a 4.7/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2021 Lexus RX vehicles in Ohio have no reported accidents or damage?

110 out of 110 for sale near Ohio have no reported accidents or damage.

Is the 2021 Lexus RX safe?

CarGurus experts gave the 2021 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2021 Lexus RX?

Depending on the engine and options, the 2021 Lexus RX gets between 21 and 23 MPG (or MPGe).

What fuel types are available?

Gasoline engines are available.

  • 2024 Lexus RX in Ohio

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  • Lexus RX 350 FWD

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