Used 2021 Mercedes-Benz E-Class for Sale Nationwide

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2021 Mercedes-Benz E-Class

E 350 RWD

81,104 miles

$25,499

Good Deal

National City, CA

1 mi away

Year:: 2021
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: Rear-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Black
Combined gas mileage:: 26 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 81,104
Stock number:: 100681
VIN:: W1KZF8DB4MA921126

2021 Mercedes-Benz E-Class

E 350 RWD

40,274 miles

$29,999

Great Deal

Certified Pre-Owned

Arcadia, CA

1 mi away

Year:: 2021
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: Rear-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Cirrus Silver Metallic
Combined gas mileage:: 26 MPG
Fuel type:: Gasoline
Interior color:: Neva White/Magma Gray
Transmission:: 9-Speed Automatic
Mileage:: 40,274
Stock number:: 35T01921
VIN:: W1KZF8DB1MA975130

2021 Mercedes-Benz E-Class

AMG 53 E Sedan 4MATIC

30,984 miles

$53,497

Fair Deal

San Jose, CA

1 mi away

Year:: 2021
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 429 hp 3L I6
Exterior color:: Gray
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Brown (Tan)
Transmission:: 9-Speed Automatic
Mileage:: 30,984
Stock number:: 12748
VIN:: W1KZF6BB3MA992504

2020 Mercedes-Benz E-Class

E 350 4MATIC AWD

58,361 miles

$24,966

Good Deal

Chicopee, MA

1 mi away

Year:: 2020
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Selenite Gray Metallic
Combined gas mileage:: 26 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 58,361
Stock number:: A771478B
VIN:: W1KZF8EB0LA771478

2020 Mercedes-Benz E-Class

E 350 4MATIC AWD

69,332 miles

$23,888

Good Deal

Whitesboro, NY

1 mi away

Year:: 2020
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Designio White Pearl
Combined gas mileage:: 26 MPG
Fuel type:: Gasoline
Interior color:: Brown (Beige)
Transmission:: 9-Speed Automatic
Mileage:: 69,332
Stock number:: LA715049
VIN:: WDDZF8EB5LA715049

2020 Mercedes-Benz E-Class

E 450 4MATIC AWD

47,730 miles

$30,687

Fair Deal

Certified Pre-Owned

Grand Rapids, MI

1 mi away

Year:: 2020
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 362 hp 3L V6
Exterior color:: Polar White
Combined gas mileage:: 24 MPG
Fuel type:: Gasoline
Interior color:: designo Macchiato Beige/Saddle Brown
Transmission:: 9-Speed Automatic
Mileage:: 47,730
Stock number:: 2846-26A
VIN:: W1KZF6JB5LA765847

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2020 Mercedes-Benz E-Class

E 350 Sedan RWD

52,290 miles

$25,986

Fair Deal

Oakland, CA

1 mi away

Year:: 2020
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: Rear-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Obsidian Black Metallic
Combined gas mileage:: 27 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 52,290
Stock number:: 18236
VIN:: WDDZF8DB6LA738213

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2021 Mercedes-Benz E-Class

E 350 4MATIC

38,326 miles

$30,464

Great Deal

Wellesley, MA

1 mi away

Year:: 2021
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Blue Metallic
Combined gas mileage:: 26 MPG
Fuel type:: Gasoline
Interior color:: Brown (Macchiato Beige/Magma Gray)
Transmission:: 9-Speed Automatic
Mileage:: 38,326
Stock number:: P0138A
VIN:: W1KZF8EB3MB000766

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2022 Mercedes-Benz E-Class

E 350 RWD

45,086 miles

$30,797

Good Deal

Certified Pre-Owned

Orlando, FL

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: Rear-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: MANUFAKTUR Cardinal Red Metallic
Combined gas mileage:: 27 MPG
Fuel type:: Gasoline
Interior color:: Brown (Macchiato Beige/Black)
Transmission:: 9-Speed Automatic
Mileage:: 45,086
Stock number:: P054464A
VIN:: W1KZF8DB0NB054464

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2021 Mercedes-Benz E-Class

E 450 Coupe RWD

51,217 miles

$37,744

Fair Deal

Bee Cave, TX

1 mi away

Year:: 2021
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Coupe
Doors:: 2 doors
Drivetrain:: Rear-Wheel Drive
Engine:: 362 hp 3L I6
Exterior color:: Black
Combined gas mileage:: 27 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 51,217
Stock number:: CP1997A
VIN:: W1K1J5JB5MF159877

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2022 Mercedes-Benz E-Class

E 350 4MATIC

36,520 miles

$35,863

Great Deal

Certified Pre-Owned

Ft Mitchell, KY

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Black
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 36,520
Stock number:: 36T3375
VIN:: W1KZF8EB4NB026164

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2021 Mercedes-Benz E-Class

AMG 53 E Sedan 4MATIC

65,442 miles

$37,729

Great Deal

Roseville, CA

1 mi away

Year:: 2021
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 429 hp 3L I6
Exterior color:: Designo Diamond White Metallic
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Brown (Macchiato Beige/Black)
Transmission:: Automatic
Mileage:: 65,442
Stock number:: MA879693
VIN:: W1KZF6BB4MA879693

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2020 Mercedes-Benz E-Class

E 450 Coupe RWD

33,937 miles

$33,963

Great Deal

Fresno, CA

1 mi away

Year:: 2020
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Coupe
Doors:: 2 doors
Drivetrain:: Rear-Wheel Drive
Engine:: 362 hp 3L V6
Exterior color:: Polar White
Combined gas mileage:: 24 MPG
Fuel type:: Gasoline
Interior color:: Macchiato Beige/Espresso Brown
Transmission:: 9-Speed Automatic
Mileage:: 33,937
Stock number:: P00812
VIN:: W1K1J6HB4LF145799

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2021 Mercedes-Benz E-Class

E 350 RWD

64,945 miles

$25,999

Great Deal

Peoria, AZ

1 mi away

Year:: 2021
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: Rear-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Black
Combined gas mileage:: 26 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 64,945
Stock number:: VW5824PA
VIN:: W1KZF8DB0MA915324

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2022 Mercedes-Benz E-Class

E 350 RWD

17,840 miles

$37,796

Great Deal

Certified Pre-Owned

Diberville, MS

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: Rear-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Obsidian Black Metallic
Combined gas mileage:: 27 MPG
Fuel type:: Gasoline
Interior color:: Brown (Macchiato Beige/Black)
Transmission:: 9-Speed Automatic
Mileage:: 17,840
Stock number:: MB2132A
VIN:: W1KZF8DB0NB080126

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2022 Mercedes-Benz E-Class

E 350 4MATIC

63,275 miles

$30,995

Great Deal

Certified Pre-Owned

Portland, OR

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Cirrus Silver Metallic
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 63,275
Stock number:: NB034206M
VIN:: W1KZF8EB1NB034206

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2020 Mercedes-Benz E-Class

E 350 4MATIC AWD

68,529 miles

$21,913

Good Deal

Ledgewood, NJ

1 mi away

Year:: 2020
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Polar White
Combined gas mileage:: 26 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 68,529
Stock number:: LA809382
VIN:: W1KZF8EB3LA809382

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2020 Mercedes-Benz E-Class

E 350 4MATIC AWD

50,282 miles

$24,400

Great Deal

Chandler, AZ

1 mi away

Year:: 2020
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Gray (Selenite Grey Metallic)
Combined gas mileage:: 26 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 50,282
Stock number:: E5O628A
VIN:: WDDZF8EB4LA755770

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2022 Mercedes-Benz E-Class

E 350 RWD

44,860 miles

$32,498

Fair Deal

Plano, TX

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: Rear-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Black
Combined gas mileage:: 27 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 44,860
Stock number:: 087792
VIN:: W1KZF8DB6NB087792

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2021 Mercedes-Benz E-Class

E 350 RWD

75,066 miles

$26,998

Fair Deal

Chandler, AZ

1 mi away

Year:: 2021
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: Rear-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: White
Combined gas mileage:: 26 MPG
Fuel type:: Gasoline
Transmission:: Automatic
Mileage:: 75,066
Stock number:: GC26213A
VIN:: W1KZF8DB0MA926775

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2022 Mercedes-Benz E-Class

E 350 RWD

30,306 miles

$34,445

Good Deal

Certified Pre-Owned

Valencia, CA

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: Rear-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Polar White
Combined gas mileage:: 27 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 30,306
Stock number:: 4P2348
VIN:: W1KZF8DB3NB090049

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2022 Mercedes-Benz E-Class

E 350 4MATIC

38,467 miles

$36,082

Good Deal

Certified Pre-Owned

Nanuet, NY

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Gray Metallic
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Neva White Magma Grey
Transmission:: 9-Speed Automatic
Mileage:: 38,467
Stock number:: B053437A
VIN:: W1KZF8EB5NB053437

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2021 Mercedes-Benz E-Class

E 350 4MATIC

44,491 miles

$31,565

Good Deal

Elmhurst, IL

1 mi away

Year:: 2021
Make:: Mercedes-Benz
Model:: E-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 255 hp 2L I4
Exterior color:: Polar White
Combined gas mileage:: 26 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 44,491
Stock number:: P5852A
VIN:: W1KZF8EB3MA905384

Overview

Reviews

FAQs

CarGurus Analysis: 2021 Mercedes-Benz E-Class

## Summary - With 921 currently listed for sale on CarGurus and an **average price of $38,281.00**, 32.4% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2021 Mercedes-Benz E-Class 4.53 / 5 stars and CarGurus experts gave it an 8.33 / 10. - **75.8% of 2021 E-Class models on CarGurus are accident free**. - The 2021 Mercedes-Benz E-Class introduced modest changes including a mid-cycle update in infotainment, engines, and exterior styling, maintaining its reputation as a versatile luxury sedan. ## Why it stands out The 2021 Mercedes-Benz E-Class differentiates itself with its luxurious interior and impeccable performance. Not only does it offer various body styles and powertrain options—including a new hybrid inline-six engine—but it also features a striking design that appeals to the luxury-savvy market. The E-Class provides a smooth ride and high-quality materials throughout the cabin, ensuring an elevated driving experience. However, some users noted concerns regarding advanced safety features and the use of artificial leather in place of genuine leather. Overall, the 2021 model remains a strong contender for those seeking a sophisticated yet practical vehicle, as highlighted in the expert review which emphasizes its blend of luxury and versatility. ## Other model years to consider - **[2022 Mercedes-Benz E-Class](https://www.cargurus.com/Cars/l-Used-2022-Mercedes-Benz-E-Class-c31854)** - Average price: $40,599.00 - Good/great deal percentage: 32.1% - User rating: 5 / 5 - Total listings: 1,088 - **[2019 Mercedes-Benz E-Class](https://www.cargurus.com/Cars/l-Used-2019-Mercedes-Benz-E-Class-c28109)** - Average price: $27,650.00 - Good/great deal percentage: 32.4% - User rating: 4.88 / 5 - Total listings: 1,161 - **[2018 Mercedes-Benz E-Class](https://www.cargurus.com/Cars/l-Used-2018-Mercedes-Benz-E-Class-c27070)** - Average price: $24,026.00 - Good/great deal percentage: 32.4% - User rating: 4.68 / 5 - Total listings: 1,301 This analysis is based on CarGurus' proprietary market data from March 2, 2026, CarGurus experts' opinions, and generative AI.

4.6 Overall rating

(17 reviews)

Teddi R

5.0

Reviewed a 2021 Mercedes-Benz E-Class on Jun 01, 2024

You cant go wrong with any of the E-class Mercedes! They are bulletproof cars with NO issues.

Anonymous

4.0

Reviewed a 2021 Mercedes-Benz E-Class on May 01, 2024

Ive owned many Mercedes over the years but always come back to Model E. Best size, forward technology and usually handsome exterior/interior

Elvis K. N

5.0

Reviewed a 2021 Mercedes-Benz E-Class on Jan 29, 2023

Very nice car but does not have active lane keeping assist.

Elvis E

5.0

Reviewed a 2021 Mercedes-Benz E 350 RWD on Apr 30, 2023

Best Car Ever! Great gas mileage. No problems so far at all! This is my 2nd Mercedes E-Class and I have no regrets buying it. Has great power. Can go really fast in seconds. If you like sporty exterior and luxury interior then this Mercedes Benz E350 2021 is the car for you!

Mark M

5.0

Reviewed a 2021 Mercedes-Benz E-Class on Feb 13, 2023

I’m not sure this is a great value but it does come with beautiful styling in my opinion and the interior is a work of art. Yes a Lexus will likely come with fewer maintenance issues and last longer but other than the LC you’ll be stuck with a boring uglier car that much longer.

2021 Mercedes-Benz E-Class FAQs

How much does the 2021 Mercedes-Benz E-Class cost?

The average 2021 Mercedes-Benz E-Class costs about $38,670.46. The average price has decreased by -4.2% since last year. The 921 for sale on CarGurus range from $15,700 to $129,999 in price.

Is the 2021 Mercedes-Benz E-Class a good car?

CarGurus experts gave the 2021 Mercedes-Benz E-Class an overall rating of 8.3/10 and 2021 Mercedes-Benz E-Class owners have rated the vehicle a 4.5/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2021 Mercedes-Benz E-Class vehicles have no reported accidents or damage?

703 out of 921 for sale have no reported accidents or damage.

Is the 2021 Mercedes-Benz E-Class safe?

CarGurus experts gave the 2021 Mercedes-Benz E-Class a safety rating of 10/10.

What is the fuel economy of the 2021 Mercedes-Benz E-Class?

Depending on the engine and options, the 2021 Mercedes-Benz E-Class gets between 18 and 27 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

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