Used 2021 Mercedes-Benz E-Class for Sale near Washington, DC
160 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 185 currently listed for sale near Washington, DC and an average price of $40,878.00, 37.3% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
87.0% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features multiple powertrain options and a cutting-edge infotainment system with improved user-friendliness.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall

Summary
With 185 currently listed for sale near Washington, DC and an average price of $40,878.00, 37.3% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
87.0% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features multiple powertrain options and a cutting-edge infotainment system with improved user-friendliness.
Why it stands out
The 2021 Mercedes-Benz E-Class stands out in the competitive midsize luxury sedan segment for its remarkable blend of performance and luxury. It offers a range of powertrains including a hybrid inline-six in the E450, delivering a balance of power and efficiency. For those seeking sporty dynamics, the AMG E53 variant adds performance-oriented enhancements while maintaining comfort. The E-Class has received updates for 2021, including a refined infotainment system that enhances the user experience with natural voice processing and an intuitive touchscreen. Its interior is marked by high-quality materials and attention to detail, providing an inviting atmosphere for both drivers and passengers. The car's safety credentials are also impressive, boasting high ratings from safety organizations, making it a wise choice for buyers prioritizing peace of mind along with luxury and performance.
Other model years to consider
- Average price: $29,632.00
- Good/great deal percentage: 31.0%
- User rating: 5 / 5
- Total listings: 229
- Average price: $39,895.00
- Good/great deal percentage: 41.2%
- User rating: 5 / 5
- Total listings: 177
- Average price: $23,854.00
- Good/great deal percentage: 25.5%
- User rating: 4.76 / 5
- Total listings: 314
This analysis is based on CarGurus' proprietary market data from April 28, 2026, CarGurus experts' opinions, and generative AI.
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4.7 Overall rating
Filter by rating
ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Teddi R
Reviewed a 2021 Mercedes-Benz E-Class on Jun 2, 2024
You cant go wrong with any of the E-class Mercedes! They are bulletproof cars with NO issues.
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
Elvis K. N
Reviewed a 2021 Mercedes-Benz E-Class on Jan 29, 2023
Very nice car but does not have active lane keeping assist.
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| AMG E 63 S Wagon 4MATIC | $112,450 |
| E 450 4MATIC Coupe AWD | $67,450 |
| E 450 Cabriolet RWD | $71,950 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| E 350 4MATIC | $56,750 |
| E 350 RWD | $54,250 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
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