Used 2021 Mercedes-Benz E-Class for Sale near Baltimore, MD
188 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 180 currently listed for sale near Baltimore, MD and an average price of $42,290.00, 34.4% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
87.2% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class received a mid-cycle update, introducing improved infotainment features, a new hybrid powertrain for higher trims, and elegant exterior styling.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall

Summary
With 180 currently listed for sale near Baltimore, MD and an average price of $42,290.00, 34.4% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
87.2% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class received a mid-cycle update, introducing improved infotainment features, a new hybrid powertrain for higher trims, and elegant exterior styling.
Why it stands out
The 2021 Mercedes-Benz E-Class excels as a luxurious midsize sedan, perfectly blending performance and comfort. Its refined ride quality and state-of-the-art technology make it a top contender in its class. The switch to electrified inline-six powertrains enhances both efficiency and performance without compromising the smooth driving experience that Mercedes is known for. Additionally, the interior stands out with premium materials, extensive customization options, and innovative tech features such as a comprehensive infotainment system with dual 12-inch displays. However, potential buyers should be aware that many advanced safety features are optional, which could increase the overall cost. Overall, the E-Class remains an attractive option for those seeking a versatile luxury vehicle that can be tailored to personal preferences.
Other model years to consider
- Average price: $40,291.00
- Good/great deal percentage: 39.4%
- User rating: 5 / 5
- Total listings: 180
- Average price: $29,563.00
- Good/great deal percentage: 29.5%
- User rating: 5 / 5
- Total listings: 220
- Average price: $24,449.00
- Good/great deal percentage: 31.0%
- User rating: 4.76 / 5
- Total listings: 316
This analysis is based on CarGurus' proprietary market data from April 21, 2026, CarGurus experts' opinions, and generative AI.
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2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
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4.7 Overall rating
Filter by rating
ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Teddi R
Reviewed a 2021 Mercedes-Benz E-Class on Jun 2, 2024
You cant go wrong with any of the E-class Mercedes! They are bulletproof cars with NO issues.
Anonymous
Reviewed a 2021 Mercedes-Benz E-Class on May 2, 2024
Ive owned many Mercedes over the years but always come back to Model E. Best size, forward technology and usually handsome exterior/interior
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| AMG E 53 Cabriolet 4MATIC | $82,850 |
| E 450 4MATIC Coupe AWD | $67,450 |
| E 450 Cabriolet RWD | $71,950 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| E 350 4MATIC | $56,750 |
| E 350 RWD | $54,250 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
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