Used 2021 Mercedes-Benz E-Class for Sale near Baltimore, MD
149 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 146 currently listed for sale near Baltimore, MD and an average price of $42,790.00, 52.1% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
95.2% of 2021 E-Class models on CarGurus are accident-free.
The 2021 Mercedes-Benz E-Class features a new infotainment system, hybrid engine options, and a beautifully designed interior that combines luxury with advanced technology.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall

Summary
With 146 currently listed for sale near Baltimore, MD and an average price of $42,790.00, 52.1% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
95.2% of 2021 E-Class models on CarGurus are accident-free.
The 2021 Mercedes-Benz E-Class features a new infotainment system, hybrid engine options, and a beautifully designed interior that combines luxury with advanced technology.
Why it stands out
The 2021 Mercedes-Benz E-Class is an exceptional entry in the luxury midsize sedan segment, celebrated for its luxurious feel coupled with powerful performance options. This model year introduces a sophisticated mid-cycle update that includes enhancements to its infotainment system, engine choices, and overall styling, ensuring it captivates users with both practicality and elegance. Notably, the E-Class is available in various configurations that range from efficient to exceedingly powerful, catering to a diverse array of driver preferences. The interior showcases high-quality materials, with rich woods and metals enhancing its luxurious ambiance. Although some drivers point out concerns regarding its pricing and the use of artificial leather, the overall user experience remains highly favorable with many praising its advanced technology and comfort features.
Other model years to consider
- Average price: $41,728.00
- Good/great deal percentage: 49.5%
- User rating: 5 / 5
- Total listings: 190
- Average price: $34,619.00
- Good/great deal percentage: 43.3%
- User rating: 5 / 5
- Total listings: 215
- Average price: $29,736.00
- Good/great deal percentage: 39.9%
- User rating: 4.76 / 5
- Total listings: 311
This analysis is based on CarGurus' proprietary market data from June 9, 2026, CarGurus experts' opinions, and generative AI.
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4.7 Overall rating
Filter by rating
ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
Elvis K. N
Reviewed a 2021 Mercedes-Benz E-Class on Jan 29, 2023
Very nice car but does not have active lane keeping assist.
Elvis E
Reviewed a 2021 Mercedes-Benz E 350 RWD on Apr 30, 2023
Best Car Ever! Great gas mileage. No problems so far at all! This is my 2nd Mercedes E-Class and I have no regrets buying it. Has great power. Can go really fast in seconds. If you like sporty exterior and luxury interior then this Mercedes Benz E350 2021 is the car for you!
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| E 450 4MATIC Coupe AWD | $67,450 |
| E 450 Cabriolet RWD | $71,950 |
| AMG E 63 S Wagon 4MATIC | $112,450 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| E 350 4MATIC | $56,750 |
| E 350 RWD | $54,250 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
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