Used 2021 Mercedes-Benz E-Class E 450 4MATIC Sedan AWD for SaleNationwide
17 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Neva White/Magma Grey Mb-
- Transmission:
- 9-Speed Automatic
- Mileage:
- 37,759
- Stock #:
- ZTC7302
- VIN:
- W1KZF5KB1MA877166
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
37,759 mi
Bend, OR
Good Deal
$37,664
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Obsidian Black Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 67,985
- Stock #:
- TT2130AP
- VIN:
- W1KZF5KB2MA885129
New arrival
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
67,985 mi
Jacksonville, NC
Fair Deal
$32,430
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 28,819
- Stock #:
- C85086A
- VIN:
- W1KZF5KB1MA878091
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
28,819 mi
Fresno, CA
Good Deal
$39,355
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Grey)
- Transmission:
- Automatic
- Mileage:
- 23,021
- Stock #:
- MB004720
- VIN:
- W1KZF5KB6MB004720
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
23,021 mi
Delray Beach, FL
Great Deal
$36,494
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Cirrus Silver
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 44,782
- Stock #:
- PIT939998
- VIN:
- W1KZF5KB6MA939998
New arrival
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
44,782 mi
Indianapolis, IN
Fair Deal
$36,361
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 89,158
- Stock #:
- XWG-MA940528
- VIN:
- W1KZF5KB7MA940528
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
89,158 mi
Elizabeth, NJ
Fair Deal
$29,880
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- 9-Speed Automatic
- Mileage:
- 46,569
- Stock #:
- CT12061
- VIN:
- W1KZF5KB1MA953422
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
46,569 mi
Manchester, CT
Fair Deal
$36,185
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- designo Diamond White Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Almond
- Transmission:
- 9-Speed Automatic
- Mileage:
- 13,254
- Stock #:
- 67995
- VIN:
- W1KZF5KB8MA967995
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
13,254 mi
Nashville, TN
Fair Deal
$43,979
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Blue
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 86,729
- Stock #:
- 920577
- VIN:
- W1KZF5KB8MA920577
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
86,729 mi
Cumming, GA
Good Deal
$29,677
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 40,311
- Stock #:
- 28961126
- VIN:
- W1KZF5KB0MA928866
Price drop
-$1,000
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
40,311 mi
Tulsa, OK
Good Deal
$38,998
$37,998
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 100,086
- Stock #:
- 26-024
- VIN:
- W1KZF5KB4MA920026
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
100,086 mi
Manchester, NH
No Rating
$28,995
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Selenite Gray Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Nut Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 55,629
- Stock #:
- A976014T
- VIN:
- W1KZF5KB2MA976014
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
55,629 mi
El Dorado Hills, CA
High Priced
$36,862
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Silver
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 69,442
- Stock #:
- 883119
- VIN:
- W1KZF5KB0MA883119
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
69,442 mi
McAllen, TX
High Priced
$33,175
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- designo Diamond White Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 43,142
- Stock #:
- MA882591
- VIN:
- W1KZF5KB8MA882591
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
43,142 mi
Georgetown, TX
High Priced
$40,208
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black (Charcoal)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 82,822
- Stock #:
- P933589
- VIN:
- W1KZF5KB3MA933589
New arrival
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
82,822 mi
Hendersonville, NC
High Priced
$33,040
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray (Graphite Grey Metallic)
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 35,130
- Stock #:
- CU023A
- VIN:
- W1KZF5KB5MB003896
Photos coming soon
New arrival
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
35,130 mi
Knoxville, TN
High Priced
$43,795
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 81,850
- Stock #:
- 18399
- VIN:
- W1KZF5KB3MA977348
New arrival
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
81,850 mi
El Paso, TX
Overpriced
$35,149
FAQs
How much does the Mercedes-Benz E-Class E 450 4MATIC Sedan AWD cost?
The average Mercedes-Benz E-Class E 450 4MATIC Sedan AWD costs about $36,173.92. The average price has decreased by -8.7% since last year. The 100 for sale on CarGurus range from $16,083 to $50,198 in price.
How many Mercedes-Benz E-Class E 450 4MATIC Sedan AWD vehicles have no reported accidents or damage?
71 out of 100 for sale have no reported accidents or damage.
What is the fuel economy of the Mercedes-Benz E-Class E 450 4MATIC Sedan AWD?
Depending on the engine and options, the Mercedes-Benz E-Class E 450 4MATIC Sedan AWD gets between 23 and 26 MPG/MPGe.
What fuel types are available?
Gasoline engines are available.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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