Used 2021 Mercedes-Benz E-Class for Sale near Miami, FL
133 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 135 currently listed for sale near Miami, FL and an average price of $47,103.00, 33.3% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
91.1% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features a sophisticated design, advanced infotainment system, and a range of powertrains, including hybrid options for improved fuel efficiency.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall

Summary
With 135 currently listed for sale near Miami, FL and an average price of $47,103.00, 33.3% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
91.1% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features a sophisticated design, advanced infotainment system, and a range of powertrains, including hybrid options for improved fuel efficiency.
Why it stands out
The 2021 Mercedes-Benz E-Class is a commendable blend of luxury, performance, and advanced technology, making it a standout choice among midsize luxury sedans. With its stunning design and refined interior, it embodies the elegance expected from the Mercedes brand. The E-Class boasts multiple body styles and engine options, allowing buyers to select a model that best fits their preferences, whether they prioritize spirited performance or fuel efficiency.
For 2021, the E-Class has received notable updates, including enhancements to the infotainment system and the introduction of hybrid powertrains that share technology with the AMG E53. This dual approach to engineering ensures that the E-Class remains powerful while adhering to stricter emissions standards. Safety is also a key element, with a suite of advanced features and a strong reputation for crashworthiness, including a five-star NHTSA rating for its sedan and wagon variants.
While some users have noted the perceived high price point and the absence of certain advanced features in base trims, the overall satisfaction from owners reflects its appeal as a luxury vehicle that justifies its cost.
Other model years to consider
- Average price: $44,483.00
- Good/great deal percentage: 37.6%
- User rating: 5 / 5
- Total listings: 165
- Average price: $24,301.00
- Good/great deal percentage: 24.1%
- User rating: 5 / 5
- Total listings: 158
- Average price: $20,767.00
- Good/great deal percentage: 19.8%
- User rating: 4.76 / 5
- Total listings: 222
This analysis is based on CarGurus' proprietary market data from June 2, 2026, CarGurus experts' opinions, and generative AI.
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4.7 Overall rating
Filter by rating
ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
Elvis K. N
Reviewed a 2021 Mercedes-Benz E-Class on Jan 29, 2023
Very nice car but does not have active lane keeping assist.
Elvis E
Reviewed a 2021 Mercedes-Benz E 350 RWD on Apr 30, 2023
Best Car Ever! Great gas mileage. No problems so far at all! This is my 2nd Mercedes E-Class and I have no regrets buying it. Has great power. Can go really fast in seconds. If you like sporty exterior and luxury interior then this Mercedes Benz E350 2021 is the car for you!
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| E 450 4MATIC Coupe AWD | $67,450 |
| E 450 Cabriolet RWD | $71,950 |
| AMG E 63 S Wagon 4MATIC | $112,450 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| E 350 4MATIC | $56,750 |
| E 350 RWD | $54,250 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
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