Used 2021 Mercedes-Benz E-Class for Sale near Houston, TX
142 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 142 currently listed for sale near Houston, TX and an average price of $36,144.00, 32.4% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
98.6% of 2021 E-Class models on CarGurus are accident-free.
The 2021 Mercedes-Benz E-Class introduced a mid-cycle update including a new infotainment system, various engine options, and a refined exterior design.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall
Summary
With 142 currently listed for sale near Houston, TX and an average price of $36,144.00, 32.4% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
98.6% of 2021 E-Class models on CarGurus are accident-free.
The 2021 Mercedes-Benz E-Class introduced a mid-cycle update including a new infotainment system, various engine options, and a refined exterior design.
Why it stands out
The 2021 Mercedes-Benz E-Class remains a compelling choice in the luxury mid-size sedan segment, distinguished by its combination of performance, comfort, and technological advancements. For 2021, this vehicle boasts a hybrid inline-six engine option that enhances both performance and fuel efficiency while still offering a smooth ride. Updates to the interior ensure a lavish feel with high-quality materials and advanced technology, highlighted by the MBUX infotainment system that supports touch, voice commands, and gesture controls. The E-Class's spacious cabin is designed for passenger comfort, featuring ample legroom and support that rivals even the best in its class. While some drivers might find the wealth of technology somewhat complex, the overall ease of driving and the comprehensive safety features make the E-Class a standout in luxury vehicles. However, it’s important to note that many advanced safety options are optional rather than standard.
Other model years to consider
- Average price: $38,063.00
- Good/great deal percentage: 37.4%
- User rating: 5 / 5
- Total listings: 147
- Average price: $32,179.00
- Good/great deal percentage: 25.0%
- User rating: 5 / 5
- Total listings: 176
- Average price: $49,194.00
- Good/great deal percentage: 38.3%
- User rating: 5 / 5
- Total listings: 107
This analysis is based on CarGurus' proprietary market data from April 28, 2026, CarGurus experts' opinions, and generative AI.
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2026 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Sitting squarely in the midsize luxury sedan segment, the 2026 Mercedes-Benz E-Class competes with the BMW 5 Series, the Audi A6, and the Lexus ES.
2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Thoroughly updated last year, the Mercedes-Benz E-Class returns for 2025 with added safety equipment, a new entry-level trim, and an AMG E 53 Hybrid version designed to deliver equal parts performance and efficiency.
4.7 Overall rating
Filter by rating
ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Teddi R
Reviewed a 2021 Mercedes-Benz E-Class on Jun 2, 2024
You cant go wrong with any of the E-class Mercedes! They are bulletproof cars with NO issues.
Anonymous
Reviewed a 2021 Mercedes-Benz E-Class on May 2, 2024
Ive owned many Mercedes over the years but always come back to Model E. Best size, forward technology and usually handsome exterior/interior
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| AMG E 63 S Wagon 4MATIC | $112,450 |
| E 450 Cabriolet RWD | $71,950 |
| E 450 4MATIC Coupe AWD | $67,450 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| E 350 RWD | $54,250 |
| E 350 4MATIC | $56,750 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
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