Used 2022 Mercedes-Benz E-Class for Sale near Houston, TX
155 results
CarGurus Analysis:
2022 Mercedes-Benz E-Class
With 147 currently listed for sale near Houston, TX and an average price of $39,350.00, 43.5% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars.
100.0% of 2022 E-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz E-Class features a luxurious cabin, advanced safety systems, and offers multiple body styles, including coupe, convertible, sedan, and station wagon.
CarGurus Analysis: 2022 Mercedes-Benz E-Class
overall

Summary
With 147 currently listed for sale near Houston, TX and an average price of $39,350.00, 43.5% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars.
100.0% of 2022 E-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz E-Class features a luxurious cabin, advanced safety systems, and offers multiple body styles, including coupe, convertible, sedan, and station wagon.
Why it stands out
The 2022 Mercedes-Benz E-Class sets itself apart in the luxury midsize car segment with its vast array of options, combining advanced technology, performance, and comfort that few competitors can match. Following a substantial refresh in 2021, the E-Class continues to impress with its variety of body styles and engine configurations. The introduction of new features, such as standard automatic high-beam headlights, enhances its appeal. With both turbocharged four-cylinder and six-cylinder engine choices, performance is robust, especially in the AMG-tuned E53 variant, which delivers an exhilarating driving experience. Its luxurious interior is complemented by the user-friendly MBUX infotainment system, making it a standout choice for buyers seeking both style and functionality.
Other model years to consider
- Average price: $45,672.00
- Good/great deal percentage: 41.1%
- User rating: 5 / 5
- Total listings: 112
- Average price: $25,842.00
- Good/great deal percentage: 26.1%
- User rating: 5 / 5
- Total listings: 161
- Average price: $29,031.00
- Good/great deal percentage: 22.8%
- User rating: 4.76 / 5
- Total listings: 241
This analysis is based on CarGurus' proprietary market data from June 2, 2026, CarGurus experts' opinions, and generative AI.
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2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
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5.0 Overall rating
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Jim S
Reviewed a 2022 Mercedes-Benz E-Class on Mar 6, 2025
The E-class is the midsize line of Mercedes cars, so it’s fine for all sizes except for very tall and large people. The new inline six cylinder is my favorite engine because it has plenty of power and is fuel efficient. Overall, the quality is here and has been for years.
Anonymous
Reviewed a 2022 Mercedes-Benz E-Class on Jul 12, 2024
Great value. 39K with 14K miles and in great condition with premium package. Took it to the Mercedes dealer for inspection and they said it was in great shape (tires, brakes, belts, filters, oil, fluid level, electronics, and even spark plugs). The interior was in pristine condition and the exterior is just as perfect.
Jim S
Reviewed a 2022 Mercedes-Benz E-Class on Mar 7, 2025
The E-class Mercedes Is the midsize car segment, and is large enough for many people who are not over 6’ 6” or more than 380 pounds in my estimation. Quality is noticed in interior seating and fit and finish. The relatively new Inline six cylinder engine has enough power with above average fuel economy. Other engines are available in four cylinder and eight cylinder variants.
Bill F
Reviewed a 2022 Mercedes-Benz E-Class on Jan 7, 2023
First class, quality material and build! You know maintenance is expensive going into it, but it is what it is.
2022 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| E 450 4MATIC Coupe AWD | $68,600 |
| AMG E 53 Coupe 4MATIC | $77,600 |
| E 450 Cabriolet RWD | $73,250 |
| E 450 Coupe RWD | $66,100 |
| E 450 4MATIC Sedan AWD | $62,750 |
| AMG E 53 Sedan 4MATIC | $75,000 |
| E 350 4MATIC | $57,450 |
| E 350 RWD | $54,950 |
2022 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz E-Class prices has changed over time.
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