Mercedes-Benz E-Class vs Mercedes-Benz CLS-Class Compare price, expert/user reviews, mpg, engines, safety, cargo capacity and other specs at a glance.

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User Ranking Drivers and owners ranked these cars in 9 categories.

New Car Pricing New listing price comparison and analysis.

2021 Mercedes-Benz E-Class
E 350 4MATIC Sedan AWD
MSRP
$56,750
Invoice
$53,345
Average Price Paid
$56,750
91 listings nationwide

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2021 Mercedes-Benz CLS-Class
CLS 450 4MATIC AWD
Incentives Find if there are incentives in your area. Enter your zip code
2021 Mercedes-Benz E-Class
E 350 4MATIC Sedan AWD
No Data Available
2021 Mercedes-Benz CLS-Class
CLS 450 4MATIC AWD
No Data Available

Expert Reviews Reviews from CarGurus experts.

2021 Mercedes-Benz E-Class
E 350 4MATIC Sedan AWD
Andrew Newton Test Drive Review:

When money is but a mild concern, a brand-new Mercedes-Benz is a reasonable purchase. The E-Class is the company's most practical and versatile car, as high-quality and necessary in a ...

2021 Mercedes-Benz CLS-Class
CLS 450 4MATIC AWD
Stephen Edelstein Preview:

The Mercedes-Benz CLS-Class is a large luxury car with coupe-like styling. It was last redesigned for the 2019 model year and gets updated tech features for 2021. It competes with cars...

No Data Available
  • Look and Feel 9
  • Performance 8
  • Form & Function 8
  • Technology 10
  • Safety 10
  • Cost-Effectiveness 5
No Data Available

Specs

2021 Mercedes-Benz E-Class
E 350 4MATIC Sedan AWD
2021 Mercedes-Benz CLS-Class
CLS 450 4MATIC AWD
Powertrain 9-Speed Automatic 9-Speed Automatic
Drivetrain
AWD
AWD
Fuel Economy, City
22 MPG
22 MPG
Fuel Economy, Highway
30 MPG
29 MPG
Fuel Tank Volume 17.4 gal 21.1 gal
Engine
Fuel Type
Gasoline
Gasoline
Power
255 hp @ 5,800 RPM
362 hp @ 5,500 RPM
Torque
273 lb-ft @ 1,800 RPM
369 lb-ft @ 1,800 RPM
Cylinders
4 cylinders
6 cylinders
Compression Ratio
10.5:1
10.5:1
Displacement
2,000 cc
3,000 cc
Bore x Stroke
3.27 in x 3.62 in
3.27 in x 3.62 in
Safety
ABS Brakes Standard Standard
Driver Airbag Standard Standard
Passenger Airbag Standard Standard
Front Side Airbags Standard Standard
Curtain Airbags Standard Standard
NHTSA Crash Test Results
Side Crash Overall 5 stars --
Side Barrier Driver 5 stars --
Side Barrier Passenger 5 stars --
Side Pole Driver 5 stars --
Rollover 5 stars --
Comfort and Convenience
Sunroof/Moonroof Standard Standard
Leather Seats -- Standard
Air Conditioning Standard Standard
Radio Standard Standard
Power Windows Standard Standard
Power Door Locks Standard Standard
Driver Power Seats Standard Standard
Passenger Power Seats Standard Standard
Interior
Maximum Seating 5 seats 5 seats
Front Legroom 41.7 in 41.9 in
Back Legroom 36.2 in 35 in
Payload and Towing
Cargo Volume 13.1 cu ft 11.9 cu ft
Maximum Payload -- 1,389 lbs
Exterior
Length 194.3 in 196.4 in
Width 81.3 in 81.5 in
Height 57.8 in 56.3 in
Wheelbase 115.7 in 115.7 in

Available Options

2021 Mercedes-Benz E-Class
E 350 4MATIC Sedan AWD

Exterior Colors

  • Black
  • Cirrus Silver Metallic
  • DESIGNO Cardinal Red Metallic
  • DESIGNO Diamond White Metallic
  • Graphite Grey Metallic
  • Lunar Blue Metallic
  • MANUFAKTUR Cardinal Red Metallic
  • MANUFAKTUR Diamond White Metallic
  • MANUFAKTUR Selenite Grey MAGNO
  • Mojave Silver Metallic
  • Obsidian Black Metallic
  • Polar White
  • Selenite Grey Metallic

Option Packages

  • Air Body Control Air Suspension
  • AMG Line Exterior
  • Acoustic Comfort Package
  • Active Multicontour Front Seats W/Massage Feature
  • DESIGNO MACCHIATO Beige/Saddle Brown Nappa Leather
  • Driver Assistance Package
  • Exterior Lighting Package
  • Head-Up Display
  • Premium Package
  • Warmth & Comfort Package
  • Wood/Leather Steering Wheel
  • MANUFAKTUR Black Piano Lacquer Trim
  • Rear Side Air Bags
  • Black, Leather Upholstery
  • Black, Nappa Leather Upholstery
  • MACCHIATO Beige/Black, Leather Upholstery
  • MACCHIATO Beige/Grey, Nappa Leather Upholstery
  • Neva Grey/Magma Grey, Leather Upholstery
  • Nut Brown/Black, Leather Upholstery
  • Nut Brown/Black, Nappa Leather Upholstery
  • Active Multicontour Front Seats W/Massage Feature
  • Heated Rear Seats
  • Panorama Roof
  • Wheels: 19" X 8.0" 10-Spoke
  • Wheels: 19" X 8.0" AMG 10-Spoke
  • Wheels: 19" X 8.0" AMG Twin 10-Spoke
  • Wheels: 19" X 8.0" AMG Twin 5-Spoke
  • Wheels: 19" X 8.0" AMG Twin 5-Spoke W/Black Accents
2021 Mercedes-Benz CLS-Class
CLS 450 4MATIC AWD

Exterior Colors

  • Black
  • Cirrus Silver Metallic
  • DESIGNO Cardinal Red Metallic
  • DESIGNO Diamond White Metallic
  • DESIGNO MANUFAKTUR Arabian Grey
  • DESIGNO MANUFAKTUR Cashmere White MAGNO
  • DESIGNO MANUFAKTUR Cote D'AZUR Light Blue Metallic
  • DESIGNO MANUFAKTUR Deep Green
  • DESIGNO MANUFAKTUR Graphite Metallic
  • DESIGNO MANUFAKTUR Teide Light Grey
  • Designo Manufaktur Midnight Blue
  • Graphite Grey Metallic
  • Lunar Blue Metallic
  • MANUFAKTUR Cardinal Red Metallic
  • MANUFAKTUR Diamond White Metallic
  • MANUFAKTUR Selenite Grey MAGNO
  • Mojave Silver Metallic
  • Obsidian Black Metallic
  • Polar White
  • Selenite Grey Metallic

Option Packages

  • Soft-Close Doors
  • AMG Line
  • Acoustic Comfort Package
  • BURMESTER Surround Sound System
  • DESIGNO Black/Titanium Grey Pearl Leather Package
  • DESIGNO MACCHIATO Beige/Titian Red Leather PKG
  • DESIGNO MANUFAKTUR Interior Styling Package
  • Driver Assistance Package
  • Exterior Lighting Package
  • Head-Up Display
  • Premium Package
  • Rear Side Airbags
  • Warmth & Comfort Package
  • DESIGNO BLK Piano Lacquer Flowing Lines Wood Trim
  • Black, Nappa Leather Upholstery
  • MACCHIATO Beige/Grey, Nappa Leather Upholstery
  • Magma Grey/Espresso, Nappa Leather Upholstery
  • Magma Grey/MACCHIATO, Nappa Leather Upholstery
  • Sahara Beige, Nappa Leather Upholstery
  • Active Multicontour Front Seats W/Massage Feature
  • Marsala Brown/Espresso, Nappa Leather Upholstery
  • Heated Rear Seats
  • Wheels: 20" AMG Black Multi-Spoke
  • Wheels: 20" AMG Multi-Spoke
  • Wheels: 20" AMG Multi-Spoke W/Black Accents
  • Wheels: 20" Twin 5-Spoke

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