2021 Lexus RX vs 2021 Toyota Sequoia
Overview | |
MSRP$45,220 | MSRP$50,400 |
Listings84 | Listings11 |
Ratings & Reviews | |
User Reviews | User Reviews |
Expert reviews7.8 out of 10 | Expert reviews7.0 out of 10 |
Pros
Cons
| Pros
Cons
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2021 Lexus RX Reviews SummaryThe body and mechanics of the midsize Lexus RX are mostly unchanged for the 2021 model year. It remains a formidable luxury SUV with comfortable accommodations and plenty of creature comforts. Lexus’ tradition of reliability extends to the RX as well. There are a few tech upgrades worth noting for 2021, including new standard safety systems. | |
2021 Toyota Sequoia Reviews SummaryLook around on the road today, and you are bound to see SUVs of all shapes and sizes. From three-row family haulers to subcompact runabouts. There is an SUV for nearly every need and every budget. The 2021 Toyota Sequoia might feel like it's from an earlier wave of the SUV craze, and that’s because it is. Born out of the 1990s SUV-excess-fest, the Sequoia has evolved into a niche vehicle for those who need serious space and truck-like capability. The current generation of the Sequoia has been around for almost 15 years, and while Toyota has updated it in several ways, there’s no avoiding its age. Even with modern tech and safety features, this is still an aging beast. Can such a dated vehicle still be relevant in the modern car market? And is age really that important to buyers who are looking for tons of space and standard V8 power? Read on to find out. | |
No video found | No video found |
Popular Features & Specs | |
Engine3.5L 295 hp V6 | Engine5.7L 381 hp V8 |
Drive TrainFWD | Drive Train4X2 |
Seating Capacity5 | Seating Capacity8 |
Horsepower295 hp @ 6300 rpm | Horsepower381 hp @ 5600 rpm |
MPG City20 | MPG City13 |
MPG Highway27 | MPG Highway17 |
Engine | |
Engine Name3.5L 295 hp V6 | Engine Name5.7L 381 hp V8 |
Torque267 lb-ft @ 4700 rpm | Torque401 lb-ft @ 3600 rpm |
Horsepower295 hp @ 6300 rpm | Horsepower381 hp @ 5600 rpm |
DrivetrainFWD | Drivetrain4X2 |
Fuel Economy | |
MPG City20 | MPG City13 |
MPG Highway27 | MPG Highway17 |
Interior | |
Seating Capacity5 | Seating Capacity8 |
Key Features | |
Sunroof/Moonroof | Sunroof/MoonroofStandard |
Safety | |
Front Crash Overall4 | Front Crash Overall |
Side Crash Overall5 | Side Crash Overall |
Dimensions & Capacity | |
Cargo Space16.0 cu ft | Cargo Space18.9 cu ft |
Curb Weight4222 lbs | Curb Weight5730 lbs |
Height67.7 in | Height77.0 in |
Length192.5 in | Length205.1 in |
Width74.6 in | Width79.9 in |
Wheelbase109.8 in | Wheelbase122.0 in |
Maximum Payload920 lbs | Maximum Payload1405 lbs |
Number of doors4 | Number of doors4 |
Maximum Towing Capacity3500 lbs | Maximum Towing Capacity7400 lbs |
Standard Towing Capacity | Standard Towing Capacity7400 lbs |
Overview | ||
MSRP | $45,220 | $50,400 |
Listings | ||
Ratings & Reviews | ||
User reviews | ||
Expert reviews | 7.8 out of 10Read full review | 7.0 out of 10Read full review |
Pros & cons | Pros
Cons
| Pros
Cons
|
Summary | The body and mechanics of the midsize Lexus RX are mostly unchanged for the 2021 model year. It remains a formidable luxury SUV with comfortable accommodations and plenty of creature comforts. Lexus’ tradition of reliability extends to the RX as well. There are a few tech upgrades worth noting for 2021, including new standard safety systems. | Look around on the road today, and you are bound to see SUVs of all shapes and sizes. From three-row family haulers to subcompact runabouts. There is an SUV for nearly every need and every budget. The 2021 Toyota Sequoia might feel like it's from an earlier wave of the SUV craze, and that’s because it is. Born out of the 1990s SUV-excess-fest, the Sequoia has evolved into a niche vehicle for those who need serious space and truck-like capability. The current generation of the Sequoia has been around for almost 15 years, and while Toyota has updated it in several ways, there’s no avoiding its age. Even with modern tech and safety features, this is still an aging beast. Can such a dated vehicle still be relevant in the modern car market? And is age really that important to buyers who are looking for tons of space and standard V8 power? Read on to find out. |
Video | No video found | No video found |
Popular Features & Specs | ||
Engine | 3.5L 295 hp V6 | 5.7L 381 hp V8 |
Drive Train | FWD | 4X2 |
Seating Capacity | 5 | 8 |
Horsepower | 295 hp @ 6300 rpm | 381 hp @ 5600 rpm |
MPG City | 20 | 13 |
MPG Highway | 27 | 17 |
Engine | ||
Engine Name | 3.5L 295 hp V6 | 5.7L 381 hp V8 |
Torque | 267 lb-ft @ 4700 rpm | 401 lb-ft @ 3600 rpm |
Horsepower | 295 hp @ 6300 rpm | 381 hp @ 5600 rpm |
Drivetrain | FWD | 4X2 |
Fuel Economy | ||
MPG City | 20 | 13 |
MPG Highway | 27 | 17 |
Interior | ||
Seating Capacity | 5 | 8 |
Key Features | ||
Sunroof/Moonroof | Standard | |
Safety | ||
Front Crash Overall | 4 | |
Side Crash Overall | 5 | |
Dimensions & Capacity | ||
Cargo Space | 16.0 cu ft | 18.9 cu ft |
Curb Weight | 4222 lbs | 5730 lbs |
Height | 67.7 in | 77.0 in |
Length | 192.5 in | 205.1 in |
Width | 74.6 in | 79.9 in |
Wheelbase | 109.8 in | 122.0 in |
Maximum Payload | 920 lbs | 1405 lbs |
Number of doors | 4 | 4 |
Maximum Towing Capacity | 3500 lbs | 7400 lbs |
Standard Towing Capacity | 7400 lbs | |
The 2021 Lexus RX showcased a modern design aesthetic that was emblematic of the brand's styling. It featured a large grille, angular headlamps, and a shapely body with a floating roof. Inside, the RX offered sumptuous seating with perforated leather upholstery, although the center console design was considered bland and somewhat dated. The RX was available in five variants, including the performance-focused RX F Sport and the extended-body RXL models with a third row of seating. Standard features included 18-inch aluminum wheels, LED lighting, and rear privacy glass, with options for larger wheels and additional exterior upgrades. The interior was well-appointed, even in the base model, with options for luxury features like semi-aniline leather upholstery and heated seats.
In contrast, the 2021 Toyota Sequoia, despite its age, maintained a robust presence with its large cabin and standard V8 power. The Sequoia's design was somewhat dated, with a massive, multi-tiered center dash reminiscent of the mid-2000s. The 2021 model introduced a new Nightshade Special Edition, but the overall design remained largely unchanged since its 2018 facelift. The Sequoia offered a spacious interior with ample headroom and legroom, particularly in the second row, and comfortable, supportive seats. It was available in several trims, including the off-road-oriented TRD Pro and the luxurious Platinum trim. The Sequoia's interior featured deep in-door pockets, a massive center console, and plenty of storage options, though newer SUVs offered better space utilization.














The 2021 Lexus RX was powered by a 3.5-liter V6 engine, delivering 295 horsepower and 267 pound-feet of torque, paired with an eight-speed automatic transmission. The RX Hybrid models combined a V6 engine with three electric motors, producing 308 horsepower. The RX offered a comfortable and dynamic driving experience, with tuning adjustments to the suspension and handling systems enhancing its performance. The RX F Sport model added features like adaptive variable suspension and sport seats for a more spirited drive. The RX achieved a top speed of 124 mph and accelerated from zero to 60 mph in 7.7 to 7.9 seconds, depending on the drivetrain.
The 2021 Toyota Sequoia came standard with a 5.7-liter V8 engine, producing 381 horsepower and 401 pound-feet of torque, paired with a six-speed automatic transmission. The Sequoia's engine provided strong acceleration, even for an SUV weighing up to 6,000 pounds. It offered a truck-like driving experience with a soft suspension and strong brakes, though it exhibited some body roll in corners. The Sequoia could tow up to 7,400 pounds, which was less than some competitors but still respectable for its class.
The 2021 Lexus RX offered a functional interior with seating for five in the two-row models and six or seven in the three-row RXL variants. Front and second-row seats provided ample space, while the third row was tight. Cargo space was limited compared to traditional SUVs, with 18.4 cubic feet behind the second row and 56.3 cubic feet with seats folded. The three-row RX offered 7.5 cubic feet behind the third row and 58.5 cubic feet with all seats folded. A power liftgate was standard, with a hands-free option available.
The 2021 Toyota Sequoia boasted a spacious cabin with nearly 19 cubic feet of cargo space behind the third row and over 66 cubic feet with it folded. With all rear seats folded, it offered 120 cubic feet of cargo space. The Sequoia featured a power-retractable rear window for easy access to the cargo area. While the front-row space could be better utilized, the Sequoia provided ample storage options, including deep in-door pockets and a massive center console.
The 2021 Lexus RX came standard with an 8-inch infotainment touchscreen, dual-zone automatic climate control, and smartphone connectivity features like Apple CarPlay and Android Auto. Upgrades included a 12.3-inch touchscreen, wireless charging, and a 15-speaker Mark Levinson surround-sound system. The infotainment system, while functional, was not the most user-friendly, and the Remote Touch controller took up valuable console space.
The 2021 Toyota Sequoia featured a 7-inch touchscreen infotainment system with Apple CarPlay, Android Auto, and Amazon Alexa. Our test model had a larger 9-inch screen, which still felt small on the large dash. The Sequoia's infotainment system was easy to use, with simple menu navigation and large hard buttons. The digital trip computer was small but functional, offering a straightforward user experience.
The 2021 Lexus RX received the IIHS Top Safety Pick designation, with Good marks on crashworthiness tests. The NHTSA rated the RX 350, RX 350L, and RX 450h with four out of five stars overall. Standard safety features included a rearview camera, 10 airbags, and the Lexus Safety System+ 2.0 suite, which offered a range of driver-assist technologies. However, the RX lacked the advanced hands-off piloting features found in some competitors.
The 2021 Toyota Sequoia came equipped with the Toyota Safety Sense-P suite, including forward-collision warning, automatic emergency braking, and adaptive cruise control. It also featured blind-spot monitoring and rear cross-traffic alert. While the Sequoia lacked more advanced safety tech, it provided a comprehensive set of standard features. The NHTSA rated the Sequoia with four out of five stars in the rollover test, but it had not been rated in other crash tests.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Lexus RX is 7.8 out of 10, while the 2021 Toyota Sequoia scores 7.0 out of 10. Based on these ratings, the 2021 Lexus RX is the recommended choice for those seeking a more refined and modern SUV experience.
Choose the 2021 Lexus RX if:
- You prioritize a modern design aesthetic and a luxurious interior.
- You value a comfortable and dynamic driving experience with hybrid options.
- You seek a vehicle with a high safety rating and comprehensive driver-assist features.
Choose the 2021 Toyota Sequoia if:
- You need a spacious cabin with ample cargo space for family and gear.
- You prefer a powerful V8 engine with strong towing capabilities.
- You appreciate straightforward technology and a truck-like driving experience.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Lexus RX is 7.8 out of 10, while the 2021 Toyota Sequoia scores 7.0 out of 10. Based on these ratings, the 2021 Lexus RX is the recommended choice for those seeking a more refined and modern SUV experience.
Choose the 2021 Lexus RX if:
Shop Now- You prioritize a modern design aesthetic and a luxurious interior.
- You value a comfortable and dynamic driving experience with hybrid options.
- You seek a vehicle with a high safety rating and comprehensive driver-assist features.
Choose the 2021 Toyota Sequoia if:
Shop Now- You need a spacious cabin with ample cargo space for family and gear.
- You prefer a powerful V8 engine with strong towing capabilities.
- You appreciate straightforward technology and a truck-like driving experience.

By: CarGurus + AI
At CarGurus, our team of experienced automotive writers remain at the heart of our content operation, conducting hands-on car tests and writing insightful guides that are backed by years of industry experience. To complement this, we are harnessing AI to make our content offering more diverse and more helpful to shoppers than ever. To achieve this, our AI systems are based exclusively on CarGurus content, ratings and data, so that what we produce is both unique to CarGurus, and uniquely helpful to car shoppers.































