2021 Lexus RX vs 2022 Toyota Sienna
Overview | |
MSRP$45,220 | MSRP$35,285 |
Listings478 | Listings585 |
Ratings & Reviews | |
User Reviews | User Reviews |
Expert reviews7.8 out of 10 | Expert reviews8.7 out of 10 |
Pros
Cons
| Pros
Cons
|
2021 Lexus RX Reviews SummaryThe body and mechanics of the midsize Lexus RX are mostly unchanged for the 2021 model year. It remains a formidable luxury SUV with comfortable accommodations and plenty of creature comforts. Lexus’ tradition of reliability extends to the RX as well. There are a few tech upgrades worth noting for 2021, including new standard safety systems. | |
2022 Toyota Sienna Reviews SummaryThe 2022 Toyota Sienna hybrid minivan rolls into the second model year following a redesign for 2021. Last year’s successful makeover with a standard hybrid powertrain returns unchanged, but a new Woodland trim level is available to attract adventurous families (or those who want to look that way). | |
No video found | No video found |
Popular Features & Specs | |
Engine3.5L 295 hp V6 | Engine2.5L 245 hp I4 Hybrid |
Drive TrainFWD | Drive TrainFWD |
Seating Capacity5 | Seating Capacity8 |
Horsepower295 hp @ 6300 rpm | Horsepower |
EV Battery Capacity | EV Battery Capacity1.9 kWh |
MPG City20 | MPG City36 |
MPG Highway27 | MPG Highway36 |
Engine | |
Engine Name3.5L 295 hp V6 | Engine Name2.5L 245 hp I4 Hybrid |
Torque267 lb-ft @ 4700 rpm | Torque |
Horsepower295 hp @ 6300 rpm | Horsepower |
DrivetrainFWD | DrivetrainFWD |
Fuel Economy | |
EV Battery Capacity | EV Battery Capacity1.9 kWh |
MPG City20 | MPG City36 |
MPG Highway27 | MPG Highway36 |
Interior | |
Seating Capacity5 | Seating Capacity8 |
Safety | |
Front Crash Overall4 | Front Crash Overall4 |
Side Crash Overall5 | Side Crash Overall5 |
Dimensions & Capacity | |
Cargo Space16.0 cu ft | Cargo Space33.5 cu ft |
Curb Weight4222 lbs | Curb Weight4610 lbs |
Height67.7 in | Height68.5 in |
Length192.5 in | Length203.7 in |
Width74.6 in | Width78.5 in |
Wheelbase109.8 in | Wheelbase120.5 in |
Maximum Payload920 lbs | Maximum Payload1560 lbs |
Number of doors4 | Number of doors4 |
Maximum Towing Capacity3500 lbs | Maximum Towing Capacity3500 lbs |
Overview | ||
MSRP | $45,220 | $35,285 |
Listings | ||
Ratings & Reviews | ||
User reviews | ||
Expert reviews | 7.8 out of 10Read full review | 8.7 out of 10Read full review |
Pros & cons | Pros
Cons
| Pros
Cons
|
Summary | The body and mechanics of the midsize Lexus RX are mostly unchanged for the 2021 model year. It remains a formidable luxury SUV with comfortable accommodations and plenty of creature comforts. Lexus’ tradition of reliability extends to the RX as well. There are a few tech upgrades worth noting for 2021, including new standard safety systems. | The 2022 Toyota Sienna hybrid minivan rolls into the second model year following a redesign for 2021. Last year’s successful makeover with a standard hybrid powertrain returns unchanged, but a new Woodland trim level is available to attract adventurous families (or those who want to look that way). |
Video | No video found | No video found |
Popular Features & Specs | ||
Engine | 3.5L 295 hp V6 | 2.5L 245 hp I4 Hybrid |
Drive Train | FWD | FWD |
Seating Capacity | 5 | 8 |
Horsepower | 295 hp @ 6300 rpm | |
EV Battery Capacity | 1.9 kWh | |
MPG City | 20 | 36 |
MPG Highway | 27 | 36 |
Engine | ||
Engine Name | 3.5L 295 hp V6 | 2.5L 245 hp I4 Hybrid |
Torque | 267 lb-ft @ 4700 rpm | |
Horsepower | 295 hp @ 6300 rpm | |
Drivetrain | FWD | FWD |
Fuel Economy | ||
EV Battery Capacity | 1.9 kWh | |
MPG City | 20 | 36 |
MPG Highway | 27 | 36 |
Interior | ||
Seating Capacity | 5 | 8 |
Safety | ||
Front Crash Overall | 4 | 4 |
Side Crash Overall | 5 | 5 |
Dimensions & Capacity | ||
Cargo Space | 16.0 cu ft | 33.5 cu ft |
Curb Weight | 4222 lbs | 4610 lbs |
Height | 67.7 in | 68.5 in |
Length | 192.5 in | 203.7 in |
Width | 74.6 in | 78.5 in |
Wheelbase | 109.8 in | 120.5 in |
Maximum Payload | 920 lbs | 1560 lbs |
Number of doors | 4 | 4 |
Maximum Towing Capacity | 3500 lbs | 3500 lbs |
The 2021 Lexus RX showcased a modern design aesthetic with its large grille, angular headlamps, shapely body, and floating roof. The interior featured sumptuous seating with perforated leather upholstery, though the center console design was considered bland and dated. Lexus offered the RX in five variants: RX, RX F Sport, RXL, RX Hybrid, and RXL Hybrid, each catering to different preferences, from base models to performance-focused and extended body versions. The 2021 model retained the elongated headlights and refined front-end design introduced in 2020, which aimed to address previous criticisms. Standard features included 18-inch aluminum wheels, LED lighting, and rear privacy glass, with available upgrades like 20-inch wheels and triple-beam LED headlights.
The 2022 Toyota Sienna embraced its minivan identity while incorporating SUV-like styling elements. It featured a macho front end and re-engineered door hinges to conceal the slider channel, giving it a sleek profile. The interior was designed to avoid the typical minivan feel, offering ample storage and comfortable seating across all rows. The second-row seats could slide up to 25 inches, making access to the third row easy. Cargo space was generous, with 33.5 cubic feet behind the third row, 75.2 cubic feet behind the second row, and 101 cubic feet behind the first row. The Sienna also boasted a 3,500-pound towing capacity and power-operated sliding doors and tailgate for added convenience.














The 2021 Lexus RX, RXL, and RX F-Sport were powered by a 3.5-liter V6 engine delivering 295 horsepower and 267 pound-feet of torque, paired with an eight-speed automatic transmission. The front-wheel-drive (FWD) RX 350 achieved 20 mpg in the city, 27 mpg on the highway, and 23 mpg combined, while all-wheel-drive (AWD) and RXL models saw slightly lower fuel efficiency. The RX Hybrid and RXL Hybrid combined a 3.5-liter V6 with three electric motors, producing 308 horsepower and achieving up to 31 mpg in the city. The RX offered a comfortable ride with targeted steering, though it exhibited some body roll at higher speeds. The F Sport Handling package added adaptive variable suspension and other performance enhancements. The RX's top speed was limited to 124 mph, with a 0-60 mph time of 7.7 to 7.9 seconds, depending on the drivetrain.
The 2022 Toyota Sienna continued with its hybrid powertrain, combining a 2.5-liter four-cylinder engine with two electric motors to produce 243 horsepower. FWD was standard, with AWD available on all trims. The AWD system used a separate electric motor for the rear wheels, simplifying the design. The Sienna's electronically controlled continuously variable transmission (CVT) offered smooth power delivery and four selectable drive modes. The TNGA platform provided better-than-expected handling for a minivan, with minimal body roll and a comfortable highway ride. The Sienna's fuel economy was impressive, with FWD models achieving 36 mpg city/highway/combined and AWD models getting 35 mpg. The 288-volt nickel metal-hydride battery pack was tucked under the front seats, and it came with a 10-year/150,000-mile warranty.
The 2021 Lexus RX was a functional SUV with seating for five in the two-row models and six or seven in the three-row RXL and RXL Hybrid. Front and second-row seats offered ample space, while the third row was tight. Cargo space in the two-row RX was 18.4 cubic feet behind the second row and 56.3 cubic feet with the seats folded. The three-row RXL provided 7.5 cubic feet behind the third row, 23 cubic feet behind the second row, and 58.5 cubic feet with both rows folded. A power liftgate was standard, with a hands-free option available.
The 2022 Toyota Sienna excelled in cargo and passenger space, capable of carrying a full 4x8 sheet of plywood with the tailgate closed. Cargo measurements were 33.5 cubic feet behind the third row, 75.2 cubic feet behind the second row, and 101 cubic feet behind the first row. The Sienna also had a 3,500-pound towing capacity. The 60/40-split third-row bench easily stored away, and each row featured storage cubbies and cupholders. Power-operated sliding doors and tailgate with foot-motion triggers added convenience for families.
The 2021 Lexus RX came with dual-zone automatic climate control, keyless entry, an 8-inch infotainment touchscreen, voice recognition, Bluetooth, Apple CarPlay, Android Auto, Amazon Alexa, satellite radio, HD Radio, a WiFi hotspot, six USB ports, and a nine-speaker sound system. Upgrades included a 12.3-inch touchscreen, additional USB ports, a moonroof, wireless charging, navigation, and a 15-speaker Mark Levinson surround-sound system. The touchpad controller for the infotainment system was functional but took up valuable center console space. The RX lacked wireless Apple CarPlay and Android Auto.
The 2022 Toyota Sienna featured a 9-inch touchscreen with Apple CarPlay, Android Auto, Amazon Alexa, SiriusXM, one USB media port, and six USB charging ports. It offered a one-year trial of Safety Connect and Remote Connect, a 10-year trial of Service Connect, and a three-month trial of AT&T WiFi Connect. Higher trims included Qi wireless charging and a 1500-watt inverter with a 120-volt AC outlet. Audio systems ranged from a six-speaker setup to a 12-speaker JBL system. A rear-seat entertainment system with an 11.6-inch display was available. The Sienna also offered a digital rearview mirror and a 10-inch head-up display on Platinum trims.
The 2021 Lexus RX received a Top Safety Pick designation from the IIHS and a four-star overall rating from the NHTSA. It came with a rearview camera, 10 airbags, enhanced vehicle stability control, and blind-spot monitoring with rear cross-traffic alert. The Lexus Safety System+ 2.0 suite included a pre-collision system, automatic emergency braking, pedestrian and cyclist detection, automatic high beams, adaptive cruise control, lane-departure warning, lane-keep assist, lane-trace assist, and road sign assist. The RX had two complete sets of LATCH connectors in the rear outboard seats.
The 2022 Toyota Sienna earned a Top Safety Pick+ rating from the IIHS and a five-star rating from the NHTSA. The Toyota Safety Sense 2.0 suite included adaptive cruise control, Lane Tracing Assist, forward collision warning, automatic emergency braking, lane departure warning, automatic high beams, and traffic sign recognition. The Star Safety System added stability control, traction control, anti-lock brakes, and electronic brake-force distribution. The Sienna had 10 airbags and multiple LATCH connectors, with a rear-seat reminder system and tire-pressure monitoring. A spare tire was available, mounted in the cargo space wall for convenience.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Lexus RX is 7.8 out of 10, while the 2022 Toyota Sienna scores 8.7 out of 10. Based on these ratings, the 2022 Toyota Sienna is the recommended choice, offering superior fuel efficiency, advanced technology, and greater versatility for families.
Choose the 2021 Lexus RX if:
- You prefer a luxury SUV with a modern design and high-quality interior materials.
- You want a variety of powertrain options, including hybrid models.
- You value a comfortable ride with advanced safety features.
Choose the 2022 Toyota Sienna if:
- You need a spacious and versatile family vehicle with excellent cargo capacity.
- You prioritize fuel efficiency with a hybrid powertrain.
- You want a minivan with advanced technology and safety features.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Lexus RX is 7.8 out of 10, while the 2022 Toyota Sienna scores 8.7 out of 10. Based on these ratings, the 2022 Toyota Sienna is the recommended choice, offering superior fuel efficiency, advanced technology, and greater versatility for families.
Choose the 2021 Lexus RX if:
Shop Now- You prefer a luxury SUV with a modern design and high-quality interior materials.
- You want a variety of powertrain options, including hybrid models.
- You value a comfortable ride with advanced safety features.
Choose the 2022 Toyota Sienna if:
Shop Now- You need a spacious and versatile family vehicle with excellent cargo capacity.
- You prioritize fuel efficiency with a hybrid powertrain.
- You want a minivan with advanced technology and safety features.

By: CarGurus + AI
At CarGurus, our team of experienced automotive writers remain at the heart of our content operation, conducting hands-on car tests and writing insightful guides that are backed by years of industry experience. To complement this, we are harnessing AI to make our content offering more diverse and more helpful to shoppers than ever. To achieve this, our AI systems are based exclusively on CarGurus content, ratings and data, so that what we produce is both unique to CarGurus, and uniquely helpful to car shoppers.



































