Used 2021 Toyota Sienna for SaleNationwide
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Fuel type:
- Gasoline
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 152,031
- Stock #:
- 044446
- VIN:
- 5TDYZ3DC5LS044446

-$1,449
2020 Toyota Sienna
XLE 7-Passenger FWD with Auto-Access Seat
152,031 mi
$19,399
$17,950
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Predawn Gray Mica
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Graphite)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 115,839
- Stock #:
- 801080B
- VIN:
- 5TDJRKEC2MS044576

2021 Toyota Sienna
XLE 7-Passenger FWD
115,839 mi
$28,811
- Year:
- 2022
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Red
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 28,124
- Stock #:
- 29803
- VIN:
- 5TDYRKEC6NS081579

2022 Toyota Sienna
XLE 7-Passenger FWD
28,124 mi
$35,210
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Red (Ruby Flare Pearl)
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Grey Flannel)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 32,904
- Stock #:
- 26UH254A
- VIN:
- 5TDDRKEC4MS008840

-$995
2021 Toyota Sienna
XSE 7-Passenger FWD
32,904 mi
$41,244
$40,249
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Super White
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Moonstone
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 81,859
- Stock #:
- T10279
- VIN:
- 5TDDRKEC7MS036051

2021 Toyota Sienna
XSE 7-Passenger FWD
81,859 mi
$37,995
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Super White
- Combined gas mileage:
- 35 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Grey Flannel)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 56,657
- Stock #:
- SF169
- VIN:
- 5TDDSKFCXMS006318

2021 Toyota Sienna
XSE 7-Passenger AWD
56,657 mi
$40,308
- Year:
- 2022
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Graphite)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 64,428
- Stock #:
- N115274T
- VIN:
- 5TDKRKEC5NS115274

2022 Toyota Sienna
LE 8-Passenger FWD
64,428 mi
$32,141
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Ash
- Transmission:
- 8-Speed Automatic
- Mileage:
- 82,151
- Stock #:
- 18P0971B
- VIN:
- 5TDYZ3DC8LS073035

-$601
2020 Toyota Sienna
Limited Premium 7-Passenger FWD
82,151 mi
$29,037
$28,436
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Super White 040
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 112,979
- Stock #:
- D27859A
- VIN:
- 5TDKRKECXMS071643

-$542
2021 Toyota Sienna
LE 8-Passenger FWD
112,979 mi
$27,350
$26,808
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Blizzard White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Hickory
- Transmission:
- 8-Speed Automatic
- Mileage:
- 101,254
- Stock #:
- 35569U
- VIN:
- 5TDYZ3DC0LS047738

2020 Toyota Sienna
XLE Premium 8-Passenger FWD
101,254 mi
$27,464
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Red (Ruby Flare Pearl)
- Combined gas mileage:
- 35 MPG
- Fuel type:
- Hybrid
- Interior color:
- Noble Brown
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 53,819
- Stock #:
- T4915B
- VIN:
- 5TDYSKFC6MS010822
2021 Toyota Sienna
XLE 7-Passenger AWD
53,819 mi
$38,077
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Red (Ruby Flare Pearl)
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Chateau
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 64,381
- Stock #:
- FPMS064271
- VIN:
- 5TDYRKEC5MS064271

-$992
2021 Toyota Sienna
XLE 7-Passenger FWD
64,381 mi
$34,690
$33,698
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Predawn Gray Mica
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Ash
- Transmission:
- 8-Speed Automatic
- Mileage:
- 115,148
- Stock #:
- 66A067A
- VIN:
- 5TDDZ3DC0LS238350

-$2,337
2020 Toyota Sienna
Limited Premium 7-Passenger AWD
115,148 mi
$30,494
$28,157
CarGurus Analysis:
2021 Toyota Sienna
With 1,379 currently listed for sale and an average price of $34,424, 34.0% of 2021 Toyota Sienna listings on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Toyota Sienna 4.33 / 5 stars and CarGurus experts gave it an 8.33 / 10.
74.8% of 2021 Toyota Sienna listings on CarGurus are accident free.
- Year:
- 2022
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 44,908
- Stock #:
- 29669
- VIN:
- 5TDDRKEC5NS124968

2022 Toyota Sienna
XSE 7-Passenger FWD
44,908 mi
$38,210
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray Flannel
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 77,900
- Stock #:
- BM11487A
- VIN:
- 5TDXRKEC6MS025295

-$1,500
2021 Toyota Sienna
XSE 7-Passenger FWD
77,900 mi
$34,572
$33,072
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Black (Charcoal)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- 8-Speed Automatic
- Mileage:
- 123,875
- VIN:
- 5TDYZ3DC4LS053770

2020 Toyota Sienna
XLE Premium 8-Passenger FWD
123,875 mi
$19,995
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Graphite)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 65,734
- Stock #:
- S049858
- VIN:
- 5TDJRKEC4MS049858

2021 Toyota Sienna
XLE 7-Passenger FWD
65,734 mi
$34,657
- Year:
- 2022
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Celestial Silver Metallic
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Gray (Grey Flannel)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 99,632
- Stock #:
- K33345A
- VIN:
- 5TDXRKEC6NS133417

2022 Toyota Sienna
XSE 7-Passenger FWD
99,632 mi
$31,579
- Year:
- 2022
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Pearl
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Chateau
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 55,929
- Stock #:
- T52246A
- VIN:
- 5TDZRKEC4NS097154

2022 Toyota Sienna
Limited 7-Passenger FWD
55,929 mi
$40,931
- Year:
- 2022
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Blue
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 62,321
- Stock #:
- 261505A
- VIN:
- 5TDKRKEC1NS091491

2022 Toyota Sienna
LE 8-Passenger FWD
62,321 mi
$31,588
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Midnight Black Metallic
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Cement
- Transmission:
- 8-Speed Automatic
- Mileage:
- 56,431
- Stock #:
- 2U2095
- VIN:
- 5TDZZ3DC9LS073257

2020 Toyota Sienna
L 7-Passenger FWD
56,431 mi
$26,048
- Year:
- 2021
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 2.5L I4 Hybrid
- Exterior color:
- Black
- Combined gas mileage:
- 36 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 142,529
- Stock #:
- 054312
- VIN:
- 5TDKRKEC1MS054312

2021 Toyota Sienna
LE 8-Passenger FWD
142,529 mi
$25,687
- Year:
- 2020
- Make:
- Toyota
- Model:
- Sienna
- Body type:
- Minivan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 296 hp 3.5L V6
- Exterior color:
- Midnight Black Metallic
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Cement
- Transmission:
- 8-Speed Automatic
- Mileage:
- 130,327
- Stock #:
- P22860A
- VIN:
- 5TDZZ3DC6LS076021

-$600
2020 Toyota Sienna
L 7-Passenger FWD
130,327 mi
$18,299
$17,699
CarGurus Analysis: 2021 Toyota Sienna
overall

Summary
With 1,379 currently listed for sale and an average price of $34,424, 34.0% of 2021 Toyota Sienna listings on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Toyota Sienna 4.33 / 5 stars and CarGurus experts gave it an 8.33 / 10.
74.8% of 2021 Toyota Sienna listings on CarGurus are accident free.
Why it stands out
The 2021 Toyota Sienna stands out because Toyota gave its minivan a major makeover for 2021, adding new style and a hybrid powertrain. It also marks the Sienna’s fourth generation of production since debuting as a 1997 model. For buyers who want a family hauler that emphasizes efficiency and comfort, that combination makes the 2021 Sienna especially distinctive.
Its strongest appeal is practical: the hybrid gasoline-electric powertrain is standard, and the Sienna is built on Toyota’s TNGA-K platform. The test-drive data also points to a fuel-efficient, spacious minivan with a great ride quality. Owner feedback reinforces those strengths, with drivers praising the roomy interior, excellent gas mileage, and smooth handling, especially for road trips.
There are a few drawbacks to keep in mind. The stereo is described as lacking, and the styling is called uninspired. Some owners also mention concerns about acceleration and interior material quality, along with missing features such as a spare tire and limited connectivity tech options.
Other model years to consider
- 2025 Toyota Sienna
- Average price: $46,403
- Good/great deal percentage: 39.5%
- User rating: 5 / 5
- Total listings: 2,490
- 2022 Toyota Sienna
- Average price: $36,585
- Good/great deal percentage: 37.1%
- User rating: 4.75 / 5
- Total listings: 1,535
- 2016 Toyota Sienna
- Average price: $17,205
- Good/great deal percentage: 31.8%
- User rating: 5 / 5
- Total listings: 1,394
Similar models to consider
- 2021 Chrysler Pacifica
- Average price: $20,545
- Good/great deal percentage: 37.3%
- User rating: 3.75 / 5
- Total listings: 2,252
- 2021 Honda Odyssey
- Average price: $26,265
- Good/great deal percentage: 37.0%
- User rating: 4.8 / 5
- Total listings: 1,386
- 2022 Kia Carnival
- Average price: $24,061
- Good/great deal percentage: 38.8%
- User rating: 4.6 / 5
- Total listings: 667
This analysis is based on CarGurus' proprietary market data from October 5, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
4.4 Overall rating
Filter by rating
Anisa S
Reviewed a 2021 Toyota LE 8-Passenger AWD on Jan 25, 2023
Good cars and valuable for big family easy access
Anonymous
Reviewed a 2021 Toyota Sienna on Oct 12, 2021
Excellent gas mileage, very roomy, and stylish interior.
Sarin J
Reviewed a 2021 Toyota Sienna on May 11, 2021
HUD, Gas mileage, Radar cruise with lane trace assist etc. makes it a great vehicle for long road trips. Wish the BSM indicators appear on the HUD and have more options displayed on the HUD as well. Also the Android Auto\Apple Car Play navigation is not projected into HUD. Wish that was included as well.
Sarah M
Reviewed a 2021 Toyota Sienna on Dec 28, 2023
I love to drive. This car floats! It turns on a dime and has some power. All the room you’ll ever need, kids not required! This car is the only car I will ever buy again!
2021 Toyota Sienna Trims
| Trim type | MSRP |
|---|---|
| Platinum 7-Passenger AWD | $50,460 |
| LE 8-Passenger AWD | $36,460 |
| Limited 7-Passenger FWD | $46,700 |
| XSE 7-Passenger FWD | $42,000 |
| XSE 7-Passenger AWD | $42,760 |
| XLE 7-Passenger AWD | $41,750 |
| LE 8-Passenger FWD | $34,460 |
| XLE 7-Passenger FWD | $39,750 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Toyota Sienna Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Toyota Sienna prices has changed over time.
See more price trends2021 Toyota Sienna Pricing Analysis
Pricing by Popular US Cities
Market Area: Nationwide
Key Insights
- Highest-Price Market: Philadelphia, PA leads with an average price of $36,617, indicating a premium demand in this area.
- Best Value: Dallas, TX offers the lowest average price at $31,028, presenting a more affordable option for buyers.
- Inventory Drives Stability: Washington, DC has the most listings at 150, suggesting a robust market presence that may stabilize prices.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Washington, DC | 150 | $32,542 |
| New York, NY | 145 | $32,475 |
| Chicago, IL | 137 | $35,169 |
| Los Angeles, CA | 129 | $31,453 |
| Philadelphia, PA | 126 | $36,617 |
| Atlanta, GA | 118 | $34,085 |
| Boston, MA | 112 | $36,050 |
| Dallas, TX | 102 | $31,028 |
| Houston, TX | 93 | $32,650 |
| Miami, FL | 72 | $33,967 |
Pricing by Trim Packages
Key Insights
- Volume Leader: The XLE 7-Passenger FWD trim has the highest inventory with 1,314 listings, indicating strong consumer preference.
- Premium Spread: The Platinum 7-Passenger AWD trim, priced at $50,460, represents the highest MSRP, highlighting a significant premium for luxury features.
- Drivetrain Effect: All trims feature the same engine, but the AWD variants generally command higher prices, reflecting consumer demand for all-wheel drive capabilities.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| XLE 7-Passenger FWD | 1,314 | $39,750 | FWD | 2.5L 245 hp I4 Hybrid |
| LE 8-Passenger FWD | 720 | $34,460 | FWD | 2.5L 245 hp I4 Hybrid |
| XLE 7-Passenger AWD | 695 | $41,750 | AWD | 2.5L 245 hp I4 Hybrid |
| XSE 7-Passenger AWD | 280 | $42,760 | AWD | 2.5L 245 hp I4 Hybrid |
| LE 8-Passenger AWD | 256 | $36,460 | AWD | 2.5L 245 hp I4 Hybrid |
| Platinum 7-Passenger AWD | 240 | $50,460 | AWD | 2.5L 245 hp I4 Hybrid |
| XLE 8-Passenger FWD | 226 | $39,750 | FWD | 2.5L 245 hp I4 Hybrid |
| XSE 7-Passenger FWD | 223 | $42,000 | FWD | 2.5L 245 hp I4 Hybrid |
Pricing Analysis by Model Year
Key Insights
- New-Car Premium: The 2026 model year shows a significant average price of $55,785, reflecting a 35.0% premium over its starting MSRP.
- Depreciation Curve: The 2015 model year exhibits the steepest depreciation at -38.1%, indicating a rapid decline in value for older models.
- Best Value Sweet Spot: The 2021 model year is priced closely to its starting MSRP at -0.1%, suggesting it may offer the best value for buyers seeking newer options without steep depreciation.
Model Year Pricing
| Model Year | Starting MSRP | Avg Price | Avg Price vs Starting MSRP |
|---|---|---|---|
| 2026 | $41,320 | $55,785 | +35.0% |
| 2025 | $39,485 | $47,116 | +19.3% |
| 2024 | $37,685 | $44,861 | +19.0% |
| 2023 | $36,885 | $40,755 | +10.5% |
| 2022 | $35,285 | $37,177 | +5.4% |
| 2021 | $34,460 | $34,422 | -0.1% |
| 2020 | $29,715 | $26,620 | -10.4% |
| 2019 | $29,390 | $25,363 | -13.7% |
| 2018 | $28,925 | $22,658 | -21.7% |
| 2017 | $27,645 | $19,778 | -28.5% |
| 2016 | $26,745 | $18,027 | -32.6% |
| 2015 | $26,595 | $16,460 | -38.1% |
These recommendations are based on CarGurus' proprietary market data from October 7, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2021 Toyota Sienna cost?
| Metric | Value |
|---|---|
| Current Average Price | $34,413 |
| Year-Round Low | $32,945 |
| Year-Round High | $35,944 |
| Average Price a Year Ago | $35,948 |
| Change vs. Last Year | −4.27% |
Prices have softened 4.27% compared to this time last year, making it a favorable time to shop this model year.
There are 1,367 listings available, which gives you a solid pool of options to compare.
Is the 2021 Toyota Sienna a good car?
Generally — the 2021 Toyota Sienna earns a 4.33/5 user rating and an 8.33/10 expert rating. The model scores 9/10 across Look and feel, Form and function, and Technology.
Drivers consistently praise the roomy interior, excellent gas mileage, and smooth handling, and many also like the AWD and hybrid combination for road trips. The overview also points to a family-focused minivan that emphasizes efficiency and comfort, which matches the owner feedback well.
The main trade-offs are the acceleration and the quality of the interior materials, plus some complaints about the stereo and limited connectivity options. For you, that means the Sienna makes the most sense if you want a practical, efficient family hauler more than a sporty or luxury-leaning one.
With 35.8% of listings marked as good or great deals, there’s enough market activity to shop selectively.
Is the 2021 Toyota Sienna reliable?
Owners rate it 4.33/5, a solid signal of long-term satisfaction.
The owner summary points to a vehicle many drivers find dependable for daily family use, with praise centered on the hybrid setup, smooth handling, and road-trip comfort. The expert notes also describe the engine, motor, and battery combination as a proven one, which supports confidence in the powertrain.
Toyota’s cost-effectiveness notes also highlight an eight-year/100,000-mile hybrid-related component warranty, which is a useful ownership cushion for a hybrid minivan. For used buyers, the main long-term risk is less about the basic concept and more about how well the specific vehicle has been maintained and used.
What should I look for when buying a used 2021 Toyota Sienna?
At 74.8% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
You should start with a vehicle history report and then prioritize a pre-purchase inspection, especially if you’re comparing multiple listings at similar prices. Focus on condition details that matter in a family minivan: interior wear, electronics, tires, and evidence of prior body repair.
Key things to evaluate:
- Trim level: The LE uses 17-inch wheels, while higher trims move up to 18-inch or 20-inch wheels, and the cabin equipment also steps up as you climb the lineup. The base trim is the most stripped-down starting point, so compare comfort and convenience features carefully if you want a better-equipped daily driver.
- Powertrain: A 2.5-liter four-cylinder engine and two electric motors make 243 horsepower, with FWD standard and AWD available across the lineup. The CVT is tuned for smooth, efficient driving, but it can blunt throttle response.
- Safety package: Toyota Safety Sense 2.0 is standard and includes full-speed range dynamic radar cruise control, lane-tracing assist, pre-collision system with pedestrian and bicyclist detection, lane-departure alert, automatic high beams, and road sign assist. The Star Safety System is also standard, along with 10 airbags, a rear-seat reminder, TPMS, and an inflator kit.
- Infotainment: A nine-inch touchscreen is standard, along with Apple CarPlay, Android Auto, Amazon Alexa, Bluetooth, and six USB charging ports. Wireless phone integration is not mentioned, and the available tech expands with trim level.
- Fuel efficiency: FWD models are rated at 36 mpg city, 36 mpg highway, and 36 mpg combined, while AWD models are rated at 35/36/35 mpg combined.
Which 2021 Toyota Sienna trim should I buy?
The 2021 Toyota Sienna is offered in 5 trim levels: LE, XLE, XSE, Limited, Platinum.
Here's the short version:
- LE: This is the entry point, but it still gets the standard hybrid powertrain, Toyota Safety Sense 2.0, a nine-inch touchscreen, and the core family-friendly packaging. It’s the value play if you want the Sienna’s efficiency and space without paying for extras.
- XLE: This is the best-value trim for many shoppers because it adds more convenience and connectivity while staying well below the upper trims. It also unlocks more available equipment, including the rear-seat entertainment system and the 1500-watt inverter.
- XSE: This trim adds a more upscale, sportier presentation with larger wheel options and more available tech. It suits you if you want a more distinctive look without jumping all the way to the luxury-oriented trims.
- Limited: This is where the Sienna starts leaning into premium comfort and tech, including the larger driver display and available upgrades like the digital rearview mirror. It’s a strong choice if you want a more polished family hauler.
- Platinum: This is the top trim, with the most advanced tech and the most upscale presentation, including the head-up display and the highest-end audio and convenience features. Choose it if you want the most fully equipped Sienna.
Toyota Safety Sense 2.0 and the Star Safety System are standard across all trims.
Is now a good time to buy a used 2021 Toyota Sienna?
This is a moderate, selective buyer’s market, so you can shop with some leverage if you’re patient.
- Deal availability: 35.8% of listings are priced as good or great deals.
- Inventory: There are 1,367 listings available.
- Price trend: Prices have softened 4.27% compared with last year.
- Clean inventory: 74.8% of listings are accident-free.
If you find a listing below $32,945, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2021 Toyota Sienna's resale value?
The current average of $34,413 sits slightly below last year's $35,948.
That softer pricing suggests the market has cooled a bit, which can help you buy more efficiently now. For a future seller, the current trend implies you may not see rapid appreciation, but you also have a model with broad family appeal and strong efficiency credentials.
Vehicles with solid owner satisfaction ratings, like this model year's 4.33/5, tend to retain buyer demand, which supports resale value over time.
Is the 2021 Toyota Sienna safe?
The 2021 Toyota Sienna gets Toyota Safety Sense 2.0 standard, including full-speed range dynamic radar cruise control, lane-tracing assist, pre-collision system with pedestrian and bicyclist detection, lane-departure alert, automatic high beams, and road sign assist.
It earns a 7/10 safety score from our experts.
The Star Safety System is also standard, along with 10 airbags, LATCH connectors, a rear-seat reminder system, TPMS, and an inflator kit. Buyers can still opt for a spare tire, and that’s worth considering if you want extra peace of mind for road trips.
Should I buy a 2021 Toyota Sienna or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 35.8% of listings are priced as good or great deals.
- At 74.8% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
- Price trend: Prices have softened 4.27% compared with last year.
- Owners rate it 4.33/5 — a solid satisfaction signal.
- Toyota’s 2021 redesign adds a standard hybrid powertrain and a major efficiency-focused makeover.
Consider the 2020 if:
- At $26,217, the 2020 costs less than the current year's $34,413 average.
- It’s the only minivan with available AWD and emphasizes space and practicality.
Consider the 2022 if:
- At $36,583, the 2022 costs more than the current year's $34,413 average.
- It adds a new Woodland trim for buyers wanting a more adventurous look.
The bottom line: If you want the redesigned hybrid Sienna with strong efficiency and broad appeal, the 2021 is the best all-around pick. If price is your top priority, the 2020 is the cheaper route, while the 2022 makes sense if you specifically want the newer trim expansion and don’t mind paying more.
These recommendations are based on CarGurus' proprietary market data from October 6, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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