Used 2021 Toyota Sienna for Sale Nationwide
1,269 results
CarGurus Analysis:
2021 Toyota Sienna
With 1,280 currently listed for sale and an average price of $33,505.00, 31.7% of 2021 Toyota Siennas for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Toyota Sienna 4.46 / 5 stars.
74.8% of 2021 Sienna models on CarGurus are accident free.
The 2021 Toyota Sienna features a brand-new hybrid powertrain, spacious seating, and advanced technology that enhance both comfort and convenience.
CarGurus Analysis: 2021 Toyota Sienna
overall

Summary
With 1,280 currently listed for sale and an average price of $33,505.00, 31.7% of 2021 Toyota Siennas for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Toyota Sienna 4.46 / 5 stars.
74.8% of 2021 Sienna models on CarGurus are accident free.
The 2021 Toyota Sienna features a brand-new hybrid powertrain, spacious seating, and advanced technology that enhance both comfort and convenience.
Why it stands out
The 2021 Toyota Sienna marks a significant evolution in the minivan segment, debuting a fully hybrid powertrain as standard across all trims. This shift not only enhances fuel efficiency—estimated at 36 mpg combined for front-wheel drive variants—but also incorporates Toyota’s robust engineering, delivering a total output of 243 horsepower. The Sienna's redesign introduces a sleek, SUV-like aesthetic that appeals to modern families while maintaining spacious interior dimensions. With thoughtful features such as a sliding second-row seating and a large cargo area that can accommodate a full sheet of plywood, the Sienna shines in practicality. While some users express concerns over interior material quality and acceleration feedback, the overall response highlights its comfort, ride quality, and family-friendly technology options, such as a comprehensive safety suite and connectivity features that cater to all passengers.
Other model years to consider
- Average price: $27,085.00
- Good/great deal percentage: 32.2%
- User rating: 4.9 / 5
- Total listings: 1,084
- Average price: $16,348.00
- Good/great deal percentage: 35.9%
- User rating: 4.73 / 5
- Total listings: 1,105
- Average price: $42,142.00
- Good/great deal percentage: 29.9%
- User rating: 4.5 / 5
- Total listings: 1,823
This analysis is based on CarGurus' proprietary market data from March 30, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles

The Best Cars for College Students in 2026
When your teen heads off to college, that often means they’ll need a car. We've compiled a list of vehicles from popular segments that can be had for approximately $7,500 with reasonable car insurance expenses.

The Best Cheap Cars for Snow in 2026
Driving in winter conditions can be hard on both cars and drivers, but you don't need to spend a fortune to find a reliable, capable car for snow driving.

The Best First Cars for New Drivers in 2026
Whether you’re learning to drive at 16 or 60, great first cars for new drivers have a few things in common: safety, reliability, and affordability. Here are ten great picks that tick all the boxes.
4.5 Overall rating
Filter by rating
Anisa S
Reviewed a 2021 Toyota LE 8-Passenger AWD on Jan 25, 2023
Good cars and valuable for big family easy access
Anonymous
Reviewed a 2021 Toyota Sienna on Oct 12, 2021
Excellent gas mileage, very roomy, and stylish interior.
Sarin J
Reviewed a 2021 Toyota Sienna on May 11, 2021
HUD, Gas mileage, Radar cruise with lane trace assist etc. makes it a great vehicle for long road trips. Wish the BSM indicators appear on the HUD and have more options displayed on the HUD as well. Also the Android Auto\Apple Car Play navigation is not projected into HUD. Wish that was included as well.
Sarah M
Reviewed a 2021 Toyota Sienna on Dec 28, 2023
I love to drive. This car floats! It turns on a dime and has some power. All the room you’ll ever need, kids not required! This car is the only car I will ever buy again!
2021 Toyota Sienna Trims
| Trim type | MSRP |
|---|---|
| LE 8-Passenger AWD | $36,460 |
| Platinum 7-Passenger FWD | $49,900 |
| Limited 7-Passenger FWD | $46,700 |
| XSE 7-Passenger AWD | $42,760 |
| XSE 7-Passenger FWD | $42,000 |
| XLE 7-Passenger AWD | $41,750 |
| XLE 7-Passenger FWD | $39,750 |
| LE 8-Passenger FWD | $34,460 |
2021 Toyota Sienna Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Toyota Sienna prices has changed over time.
See more price trends








