Used 2021 Mercedes-Benz S-Class for Sale near California
178 results
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Manufaktur Diamond White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray (Macchiato/Magma Grey)
- Transmission:
- Automatic
- Mileage:
- 28,186
- Stock #:
- NA085063
- VIN:
- W1K6G6DB2NA085063
Sponsored by House of Imports
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
28,186 mi
$58,480
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 19 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 21,865
- Stock #:
- 12530
- VIN:
- W1K6X7GB9NA078841
Sponsored Listing
2022 Mercedes-Benz S-Class
Maybach S 580 4MATIC AWD
21,865 mi
$129,993
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- MANUFAKTUR Diamond White
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 31,884
- Stock #:
- 3P2944
- VIN:
- W1K6G7GB8NA156946
Sponsored Listing
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
31,884 mi
$69,577
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 463 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 67,442
- Stock #:
- R528168
- VIN:
- W1KUG8DB8LA528168
2020 Mercedes-Benz S-Class
S 560 Sedan RWD
67,442 mi
$36,229
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 3L V6
- Exterior color:
- designo Diamond White Metallic
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige/Tan)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 29,891
- Stock #:
- 8926
- VIN:
- WDDUG6GBXLA505412
2020 Mercedes-Benz S-Class
S 450 Sedan RWD
29,891 mi
$40,888
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- Automatic
- Mileage:
- 22,154
- Stock #:
- PNA078679
- VIN:
- W1K6G6DB6NA078679
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
22,154 mi
$61,082
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 463 hp 4L V8
- Exterior color:
- Gray (Selenite Grey M)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 42,809
- Stock #:
- 522209MM
- VIN:
- WDDUG8GB5LA522209
2020 Mercedes-Benz S-Class
S 560 4MATIC Sedan AWD
42,809 mi
$43,340
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 3L V6
- Exterior color:
- Black
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 19,945
- Stock #:
- 3366
- VIN:
- W1KUG6GB5LA528838
2020 Mercedes-Benz S-Class
S 450 Sedan RWD
19,945 mi
$40,053
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Manufaktur Diamon
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 39,343
- Stock #:
- 16837P
- VIN:
- W1K6G6DB7NA106814
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
39,343 mi
$57,985
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 14,399
- Stock #:
- 3P2881
- VIN:
- W1K6G6DB8NA165080
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
14,399 mi
$67,577
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 44,008
- Stock #:
- 8XF01507
- VIN:
- W1K6G7GBXNA139727
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
44,008 mi
$63,888
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 55,547
- Stock #:
- NA156055
- VIN:
- W1K6G7GB6NA156055
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
55,547 mi
$57,490
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Gray
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 48,097
- Stock #:
- 056771
- VIN:
- W1K6G7GB5MA056771
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
48,097 mi
$59,290
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 782 currently listed for sale and an average price of $61,950.00, 32.2% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
83.8% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a new sophisticated infotainment system, powerful engine options, and improved aerodynamics, making it a standout in the luxury sedan market.
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- MANUFAKTUR Selenite Gray Magno
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 43,177
- Stock #:
- 3P2901
- VIN:
- W1K6G7GB6NA141751
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
43,177 mi
$68,477
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Manufaktur Diamond White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 54,876
- Stock #:
- 26305
- VIN:
- W1K6G6DB8NA166553
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
54,876 mi
$48,897
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Porcelain / Espresso Brown Nap
- Transmission:
- 9-Speed Automatic
- Mileage:
- 26,229
- Stock #:
- P9687
- VIN:
- W1K6G7GB5MA022619
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
26,229 mi
$64,995
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 463 hp 4L V8
- Exterior color:
- Blue
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 48,212
- Stock #:
- 226333
- VIN:
- W1KUG8DB5LA560012
2020 Mercedes-Benz S-Class
S 560 Sedan RWD
48,212 mi
$41,084
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Gray (Graphite Grey)
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 18,821
- Stock #:
- NA166316
- VIN:
- W1K6G6DB5NA166316
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
18,821 mi
$59,988
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 19 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 21,865
- Stock #:
- 12530
- VIN:
- W1K6X7GB9NA078841
2022 Mercedes-Benz S-Class
Maybach S 580 4MATIC AWD
21,865 mi
$129,993
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 77,795
- Stock #:
- 12435
- VIN:
- W1KUG8JB0LA555143
2020 Mercedes-Benz S-Class
S AMG 63 4MATIC Sedan AWD
77,795 mi
$64,993
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Graphite Gray Metallic
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 32,848
- Stock #:
- 3P2859
- VIN:
- W1K6G6DB1NA142417
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
32,848 mi
$61,577
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Nautical Blue Metallic
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Magma Gray)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 30,066
- Stock #:
- 3P2850
- VIN:
- W1K6G6DB2NA142510
-$1,600
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
30,066 mi
$63,177
$61,577
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 44,008
- Stock #:
- 8XF01507
- VIN:
- W1K6G7GBXNA139727
Sponsored Listing
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
44,008 mi
$63,888
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 782 currently listed for sale and an average price of $61,950.00, 32.2% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
83.8% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a new sophisticated infotainment system, powerful engine options, and improved aerodynamics, making it a standout in the luxury sedan market.
Why it stands out
The 2021 Mercedes-Benz S-Class is a flagship model that epitomizes luxury and technological innovation. It comes equipped with impressive engine options, including the S500 with 429 horsepower and the S580 featuring a robust V8 engine, delivering both exhilarating performance and comfort. Notably, the S-Class introduces a mild-hybrid system, enhancing efficiency without compromising power. Owners appreciate the luxurious interior, characterized by high-quality materials, ambient lighting, and cutting-edge technology, including a 12.3-inch digital instrument cluster and a large OLED touchscreen. In terms of safety, it offers a suite of advanced driver-assist features that enhance the overall driving experience. While some reviews mention the high price and potential issues with run-flat tires, its blend of performance, comfort, and advanced tech makes it a compelling choice for luxury vehicle buyers.
Other model years to consider
- Average price: $79,591.00
- Good/great deal percentage: 32.4%
- User rating: Not available
- Total listings: 1,250
- Average price: $65,142.00
- Good/great deal percentage: 32.6%
- User rating: 4.5 / 5
- Total listings: 1,149
- Average price: $25,984.00
- Good/great deal percentage: 34.3%
- User rating: 4.95 / 5
- Total listings: 944
This analysis is based on CarGurus' proprietary market data from June 15, 2026, CarGurus experts' opinions, and generative AI.
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4.0 Overall rating
Filter by rating
Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
See more price trends
