Used 2021 Mercedes-Benz S-Class for Sale near Los Angeles, CA
183 results
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 184 currently listed for sale near Los Angeles, CA and an average price of $60,850.00, 31.0% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
92.4% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a luxurious feel, advanced technology, and remarkable performance, with two powerful engine options and a sophisticated infotainment system.
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 184 currently listed for sale near Los Angeles, CA and an average price of $60,850.00, 31.0% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
92.4% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a luxurious feel, advanced technology, and remarkable performance, with two powerful engine options and a sophisticated infotainment system.
Why it stands out
The 2021 Mercedes-Benz S-Class continues to assert its dominance as a flagship luxury sedan with impressive technological innovations and superior comfort. Its redesign includes an upgraded infotainment system and the introduction of new powertrains, with the base S500 utilizing a 429-horsepower inline-six engine and the S580 featuring a robust 496-horsepower twin-turbo V8. Both models incorporate a mild-hybrid system known as EQ Boost, which enhances fuel efficiency while delivering exceptional performance. The car is also equipped with advanced driver-assist features, including adaptive cruise control and automated lane centering, enhancing safety without compromising luxury. Mercedes has placed significant focus on the interior experience, offering high-quality materials and a minimalist design that elevates the passenger experience. However, while it excels in numerous areas, the high price point may be a barrier for some potential buyers. Overall, the 2021 S-Class remains a compelling choice for those seeking luxury, performance, and cutting-edge technology in their vehicle.
Other model years to consider
- Average price: $79,195.00
- Good/great deal percentage: 29.2%
- Total listings: 295
- Average price: $66,898.00
- Good/great deal percentage: 30.6%
- User rating: 4.5 / 5
- Total listings: 265
- Average price: $43,357.00
- Good/great deal percentage: 28.3%
- User rating: 4.9 / 5
- Total listings: 127
This analysis is based on CarGurus' proprietary market data from May 19, 2026, CarGurus experts' opinions, and generative AI.
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Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
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