Used 2022 Mercedes-Benz S-Class for Sale Nationwide

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2023 Mercedes-Benz S-Class

S 500 4MATIC AWD

18,805 miles

$63,500

Great Deal

Gaithersburg, MD

1 mi away

Year:: 2023
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 429 hp 3L I6
Exterior color:: MANUFAKTUR Diamond White
Combined gas mileage:: 24 MPG
Fuel type:: Gasoline
Interior color:: Gray (Macchiato/Magma Grey)
Transmission:: 9-Speed Automatic
Mileage:: 18,805
Stock number:: 205118
VIN:: W1K6G6DB7PA205118

2022 Mercedes-Benz S-Class

S 500 4MATIC AWD

38,810 miles

$54,900

Great Deal

Riverside, CA

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 429 hp 3L I6
Exterior color:: MANUFAKTUR Cashmere White Magno
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 38,810
Stock number:: 26T0391A
VIN:: W1K6G6DB2NA126520

2021 Mercedes-Benz S-Class

S 580 Sedan 4MATIC

53,222 miles

$52,998

Great Deal

Certified Pre-Owned

Somerville, MA

1 mi away

Year:: 2021
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 496 hp 4L V8
Exterior color:: Anthracite Blue
Combined gas mileage:: 21 MPG
Fuel type:: Gasoline
Interior color:: Sienna Brown/Black
Transmission:: 9-Speed Automatic
Mileage:: 53,222
Stock number:: M357077A
VIN:: W1K6G7GB4MA020991

2022 Mercedes-Benz S-Class

S 500 4MATIC AWD

35,772 miles

$59,184

Great Deal

Certified Pre-Owned

Augusta, GA

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 429 hp 3L I6
Exterior color:: Rubellite Red
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Carmine Red/Black
Transmission:: 9-Speed Automatic
Mileage:: 35,772
Stock number:: NA144602
VIN:: W1K6G6DB6NA144602

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

37,943 miles

$62,990

Great Deal

Certified Pre-Owned

Romeoville, IL

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 496 hp 4L V8
Exterior color:: Gray
Combined gas mileage:: 20 MPG
Fuel type:: Gasoline
Interior color:: Gray
Transmission:: Automatic
Mileage:: 37,943
Stock number:: P0475
VIN:: W1K6G7GB1NA161387

2022 Mercedes-Benz S-Class

S 500 4MATIC AWD

22,310 miles

$66,898

Fair Deal

Certified Pre-Owned

Egg Harbor Township, NJ

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 429 hp 3L I6
Exterior color:: Nautical Blue Metallic
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Macchiato/Magma Gray
Transmission:: Automatic
Mileage:: 22,310
Stock number:: NA067138P
VIN:: W1K6G6DB5NA067138

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2022 Mercedes-Benz S-Class

S 500 4MATIC AWD

31,349 miles

$61,998

Fair Deal

San Luis Obispo, CA

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 429 hp 3L I6
Exterior color:: Black
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 31,349
Stock number:: P4611
VIN:: W1K6G6DB7NA073829

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2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

42,212 miles

$59,632

Great Deal

Tamarac, FL

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 496 hp 4L V8
Exterior color:: Black
Combined gas mileage:: 20 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 42,212
Stock number:: N236515A
VIN:: W1K6G7GB6NA164656

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2021 Mercedes-Benz S-Class

S 580 Sedan 4MATIC

70,411 miles

$55,787

Fair Deal

Sacramento, CA

1 mi away

Year:: 2021
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 496 hp 4L V8
Combined gas mileage:: 21 MPG
Fuel type:: Gasoline
Transmission:: Automatic
Mileage:: 70,411
Stock number:: 6024
VIN:: W1K6G7GB3MA028158

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2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

25,565 miles

$74,999

Fair Deal

Troy, MI

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 496 hp 4L V8
Exterior color:: MANUFAKTUR Diamond White
Combined gas mileage:: 20 MPG
Fuel type:: Gasoline
Interior color:: Exclusive Carmine Red/Black
Transmission:: 9-Speed Automatic
Mileage:: 25,565
Stock number:: 5TA176P
VIN:: W1K6G7GB6NA111018

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2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

73,191 miles

$54,998

Good Deal

Certified Pre-Owned

Duluth, GA

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 496 hp 4L V8
Exterior color:: MANUFAKTUR Diamond White
Combined gas mileage:: 20 MPG
Fuel type:: Gasoline
Interior color:: Macchiato/Magma Gray
Transmission:: 9-Speed Automatic
Mileage:: 73,191
Stock number:: M17455A
VIN:: W1K6G7GB7NA073394

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2021 Mercedes-Benz S-Class

S 580 Sedan 4MATIC

19,366 miles

$66,320

Good Deal

Certified Pre-Owned

Phoenix, AZ

1 mi away

Year:: 2021
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 496 hp 4L V8
Exterior color:: Diamond White
Combined gas mileage:: 21 MPG
Fuel type:: Gasoline
Interior color:: Silver Grey/Black
Transmission:: 9-Speed Automatic
Mileage:: 19,366
Stock number:: S15323A
VIN:: W1K6G7GB8MA057512

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2022 Mercedes-Benz S-Class

S 500 4MATIC AWD

31,714 miles

$59,995

Fair Deal

Chamblee, GA

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 429 hp 3L I6
Exterior color:: Black
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 31,714
Stock number:: 079413
VIN:: W1K6G6DB6NA079413

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2022 Mercedes-Benz S-Class

S 500 4MATIC AWD

43,390 miles

$54,798

Great Deal

Certified Pre-Owned

Somerville, MA

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 429 hp 3L I6
Exterior color:: Black
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 43,390
Stock number:: M102654B
VIN:: W1K6G6DB4NA119276

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2022 Mercedes-Benz S-Class

S 500 4MATIC AWD

13,989 miles

$64,979

Great Deal

Certified Pre-Owned

Coral Gables, FL

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 429 hp 3L I6
Exterior color:: Black
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 13,989
Stock number:: U155338
VIN:: W1K6G6DB4NA155338

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2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

61,451 miles

$57,995

Good Deal

Bergenfield, NJ

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 496 hp 4L V8
Exterior color:: Black
Combined gas mileage:: 20 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 61,451
Stock number:: MS2361
VIN:: W1K6G7GB9NA072361

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2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

35,682 miles

$67,995

Good Deal

Strongsville, OH

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 496 hp 4L V8
Exterior color:: MANUFAKTUR Diamond White
Combined gas mileage:: 20 MPG
Fuel type:: Gasoline
Interior color:: Macchiato/Magma Gray
Transmission:: 9-Speed Automatic
Mileage:: 35,682
Stock number:: N0042
VIN:: W1K6G7GB4NA068914

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2023 Mercedes-Benz S-Class

S 500 4MATIC AWD

13,344 miles

$71,995

Good Deal

Jacksonville, FL

1 mi away

Year:: 2023
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 429 hp 3L I6
Exterior color:: Cirrus Silver Metallic
Combined gas mileage:: 24 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 13,344
Stock number:: PR6298
VIN:: W1K6G6DB7PA190183

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2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

16,591 miles

$72,778

Good Deal

Certified Pre-Owned

Sycamore, IL

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 496 hp 4L V8
Exterior color:: Black
Combined gas mileage:: 20 MPG
Fuel type:: Gasoline
Interior color:: Black Nappa
Transmission:: 9-Speed Automatic
Mileage:: 16,591
Stock number:: 40P1286
VIN:: W1K6G7GB8NA099163

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2021 Mercedes-Benz S-Class

S 580 Sedan 4MATIC

45,944 miles

$57,596

Fair Deal

Tampa, FL

1 mi away

Year:: 2021
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 496 hp 4L V8
Exterior color:: Obsidian Black/designo Diamon White
Combined gas mileage:: 21 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 45,944
Stock number:: X288331A
VIN:: W1K6G7GB6MA027263

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2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

23,198 miles

$69,800

Good Deal

East Hartford, CT

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 496 hp 4L V8
Exterior color:: Black
Combined gas mileage:: 20 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 23,198
Stock number:: X19540B
VIN:: W1K6G7GB4NA142459

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2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

41,561 miles

$59,985

Great Deal

Sandy Springs, GA

1 mi away

Year:: 2022
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 496 hp 4L V8
Exterior color:: Silver
Combined gas mileage:: 20 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 9-Speed Automatic
Mileage:: 41,561
Stock number:: 136342
VIN:: W1K6G7GB8NA136342

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2021 Mercedes-Benz S-Class

S 580 Sedan 4MATIC

54,756 miles

$53,995

Good Deal

Naugatuck, CT

1 mi away

Year:: 2021
Make:: Mercedes-Benz
Model:: S-Class
Body type:: Sedan
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 496 hp 4L V8
Exterior color:: Black
Combined gas mileage:: 21 MPG
Fuel type:: Gasoline
Transmission:: 9-Speed Automatic
Mileage:: 54,756
Stock number:: 59347N
VIN:: W1K6G7GB7MA059347

Overview

Reviews

FAQs

The 2022 Mercedes-Benz S-Class sedan is the very model of modern executive transportation.

The 2022 Mercedes-Benz S-Class is a full-size four-door luxury sedan with a 48-volt mild hybrid gasoline-electric powertrain, including a turbocharged 3.0-liter inline six-cylinder gas engine (S500) or twin-turbo 4.0-liter V8 (S580), with EQ Boost, a nine-speed automatic transmission, and all-wheel drive (AWD). The S500 starts at $111,100; the S580 starts at $117,700. The EPA estimates the S500 can achieve fuel economy of up to 21 mpg city/30 mpg highway/24 mpg combined, while the S580 is rated at 16 mpg city/25 mpg highway/19 mpg combined.

4.8 Overall rating

(15 reviews)

Anonymous

5.0

Reviewed a 2022 Mercedes-Benz S-Class on Jun 06, 2024

The only option I wish it had was the premier stereo system. Otherwise the car was perfect. It was basically a new vehicle. The price I actually paid was great based on the immaculate condition and very low mileage.

Joyce E

5.0

Reviewed a 2022 Mercedes-Benz S-Class on Apr 18, 2024

This car has a manufacturer recall on its fuel pump mechanism, and it is a hybrid car, so for someone who leaves the car parked in the garage for 2 straight weeks, it may cause the battery to die and may not be suited for my needs/lifestyle

Nabeel J

5.0

Reviewed a 2022 Mercedes-Benz S-Class on Apr 25, 2022

The S Class provides safety and comfort for its riders. At first, I decided to purchase the BMW 745e after comparing it with the Audi A8. I decided to give the Mercedes S class a try. After the test drive, I immediately decided to purchase the Mercedes S580. I do not regret my purchase at all. All of the looks of the car look fabulous. The ambient lighting is breathtaking as well as the display screen. The panoramic sunroof is also one of my favorites. I live in a hilly area, but I can’t even tell when going up the hill since the S580 is a powerful vehicle.

Sajid S

3.0

Reviewed a 2022 Mercedes-Benz S-Class on Dec 27, 2021

It’s been a pinnacle of luxury, however nothing stands out compared to previous models except some businesses including indoor lighting etc. the screen seems odd ;stands out in the middle and does not merge with the rest of the dashboard

Anonymous

5.0

Reviewed a 2022 Mercedes-Benz S-Class on Jan 27, 2025

Love the new car... The MB technology is amazing. The styling and comfort is some of the best in class

2022 Mercedes-Benz S-Class FAQs

How much does the 2022 Mercedes-Benz S-Class cost?

The average 2022 Mercedes-Benz S-Class costs about $67,567.42. The average price has decreased by -6.7% since last year. The 1016 for sale on CarGurus range from $45,005 to $419,750 in price.

Is the 2022 Mercedes-Benz S-Class a good car?

CarGurus experts gave the 2022 Mercedes-Benz S-Class an overall rating of 8.7/10 and 2022 Mercedes-Benz S-Class owners have rated the vehicle a 4.8/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Mercedes-Benz S-Class vehicles have no reported accidents or damage?

895 out of 1016 for sale have no reported accidents or damage.

Is the 2022 Mercedes-Benz S-Class safe?

CarGurus experts gave the 2022 Mercedes-Benz S-Class a safety rating of 9/10.

What is the fuel economy of the 2022 Mercedes-Benz S-Class?

Depending on the engine and options, the 2022 Mercedes-Benz S-Class gets between 15 and 48 MPG (or EV battery range).

What fuel types are available?

Gasoline, Hybrid engines are available.

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