Used 2022 Mercedes-Benz S-Class for Sale near Houston, TX
234 results
CarGurus Analysis:
2022 Mercedes-Benz S-Class
With 235 currently listed for sale near Houston, TX and an average price of $69,549.00, 15.3% of 2022 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
93.6% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class features a luxurious design, a powerful 48-volt mild hybrid powertrain with choices of a turbocharged inline-six or a twin-turbo V8, and advanced safety and tech features.
CarGurus Analysis: 2022 Mercedes-Benz S-Class
overall

Summary
With 235 currently listed for sale near Houston, TX and an average price of $69,549.00, 15.3% of 2022 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
93.6% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class features a luxurious design, a powerful 48-volt mild hybrid powertrain with choices of a turbocharged inline-six or a twin-turbo V8, and advanced safety and tech features.
Why it stands out
The 2022 Mercedes-Benz S-Class is the epitome of luxury and performance in executive transportation. Enhanced from previous models, it boasts a sleek exterior designed for elegance and modernity, effectively standing out in a market increasingly dominated by SUVs. The S-Class offers powertrain options including a turbocharged inline-six and a twin-turbocharged V8, both paired with a nine-speed automatic transmission for a smooth and responsive drive. With features like the revolutionary EQ Boost system, passengers enjoy seamless acceleration, making it both powerful and efficient. Inside, the vehicle impresses with high-quality materials, outstanding tech like a 12.8-inch OLED touchscreen, and features aimed at passenger comfort, like heated multicontour seats. With a competitive expert rating of 8.67 / 10, this luxury sedan balances performance, technology, and comfort in a way that few rivals can match.
Other model years to consider
- Average price: $87,646.00
- Good/great deal percentage: 14.7%
- User rating: Not available
- Total listings: 259
- Average price: $26,967.00
- Good/great deal percentage: 13.4%
- User rating: 5 / 5
- Total listings: 186
- Average price: $33,952.00
- Good/great deal percentage: 18.9%
- User rating: 4.79 / 5
- Total listings: 164
This analysis is based on CarGurus' proprietary market data from April 28, 2026, CarGurus experts' opinions, and generative AI.
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4.5 Overall rating
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Anonymous
Reviewed a 2022 Mercedes-Benz S-Class on Jun 7, 2024
The only option I wish it had was the premier stereo system. Otherwise the car was perfect. It was basically a new vehicle. The price I actually paid was great based on the immaculate condition and very low mileage.
Nabeel J
Reviewed a 2022 Mercedes-Benz S-Class on Apr 25, 2022
The S Class provides safety and comfort for its riders. At first, I decided to purchase the BMW 745e after comparing it with the Audi A8. I decided to give the Mercedes S class a try. After the test drive, I immediately decided to purchase the Mercedes S580. I do not regret my purchase at all. All of the looks of the car look fabulous. The ambient lighting is breathtaking as well as the display screen. The panoramic sunroof is also one of my favorites. I live in a hilly area, but I can’t even tell when going up the hill since the S580 is a powerful vehicle.
Sajid S
Reviewed a 2022 Mercedes-Benz S-Class on Dec 27, 2021
It’s been a pinnacle of luxury, however nothing stands out compared to previous models except some businesses including indoor lighting etc. the screen seems odd ;stands out in the middle and does not merge with the rest of the dashboard
Joyce E
Reviewed a 2022 Mercedes-Benz S-Class on Apr 18, 2024
This car has a manufacturer recall on its fuel pump mechanism, and it is a hybrid car, so for someone who leaves the car parked in the garage for 2 straight weeks, it may cause the battery to die and may not be suited for my needs/lifestyle
2022 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| S 580 4MATIC AWD | $117,700 |
| S 500 4MATIC AWD | $111,100 |
| Maybach S 680 4MATIC AWD | $229,000 |
| Maybach S 580 4MATIC AWD | $184,900 |
2022 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz S-Class prices has changed over time.
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