Used 2022 Mercedes-Benz S-Class for Sale near Philadelphia, PA
268 results
CarGurus Analysis:
2022 Mercedes-Benz S-Class
- With 262 currently listed for sale near Philadelphia, PA and an average price of $67,786.00, 25.6% of 2022 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
- Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
- 90.1% of 2022 S-Class models on CarGurus are accident free.
CarGurus Analysis: 2022 Mercedes-Benz S-Class
overall

Summary
- With 262 currently listed for sale near Philadelphia, PA and an average price of $67,786.00, 25.6% of 2022 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
- Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
- 90.1% of 2022 S-Class models on CarGurus are accident free.
Why it stands out
The 2022 Mercedes-Benz S-Class excels as a full-size luxury sedan with its seamless combination of performance, comfort, and cutting-edge technology. With its 48-volt mild hybrid gasoline-electric powertrain, the S-Class offers impressive performance metrics: the S500 makes 429 horsepower while achieving up to 21 mpg in the city and 30 mpg on the highway. The stunning interior showcases premium materials and advanced features like a 12.8-inch OLED touchscreen and a 12.3-inch digital instrument panel, appealing to both tech enthusiasts and luxury seekers. Additionally, its array of safety features, including adaptive cruise control and active lane-keeping assist, underscores Mercedes-Benz's commitment to safety innovation. The S-Class maintains a balance of elegance with a sleek design, though its high price tag and potentially polarizing aesthetics may deter some buyers.
Other model years to consider
- Average price: $75,386.00
- Good/great deal percentage: 23.4%
- Total listings: 274
- Average price: $27,326.00
- Good/great deal percentage: 25.3%
- User rating: 5 / 5
- Total listings: 257
- Average price: $45,091.00
- Good/great deal percentage: 31.1%
- User rating: 4.9 / 5
- Total listings: 219
This analysis is based on CarGurus' proprietary market data from April 21, 2026, CarGurus experts' opinions, and generative AI.
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4.5 Overall rating
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Anonymous
Reviewed a 2022 Mercedes-Benz S-Class on Jun 7, 2024
The only option I wish it had was the premier stereo system. Otherwise the car was perfect. It was basically a new vehicle. The price I actually paid was great based on the immaculate condition and very low mileage.
Nabeel J
Reviewed a 2022 Mercedes-Benz S-Class on Apr 25, 2022
The S Class provides safety and comfort for its riders. At first, I decided to purchase the BMW 745e after comparing it with the Audi A8. I decided to give the Mercedes S class a try. After the test drive, I immediately decided to purchase the Mercedes S580. I do not regret my purchase at all. All of the looks of the car look fabulous. The ambient lighting is breathtaking as well as the display screen. The panoramic sunroof is also one of my favorites. I live in a hilly area, but I can’t even tell when going up the hill since the S580 is a powerful vehicle.
Sajid S
Reviewed a 2022 Mercedes-Benz S-Class on Dec 27, 2021
It’s been a pinnacle of luxury, however nothing stands out compared to previous models except some businesses including indoor lighting etc. the screen seems odd ;stands out in the middle and does not merge with the rest of the dashboard
Joyce E
Reviewed a 2022 Mercedes-Benz S-Class on Apr 18, 2024
This car has a manufacturer recall on its fuel pump mechanism, and it is a hybrid car, so for someone who leaves the car parked in the garage for 2 straight weeks, it may cause the battery to die and may not be suited for my needs/lifestyle
2022 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| S 580 4MATIC AWD | $117,700 |
| S 500 4MATIC AWD | $111,100 |
| Maybach S 680 4MATIC AWD | $229,000 |
| Maybach S 580 4MATIC AWD | $184,900 |
2022 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz S-Class prices has changed over time.
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