Used 2021 Mercedes-Benz S-Class for Sale near Philadelphia, PA
188 results
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 179 currently listed for sale near Philadelphia, PA and an average price of $60,022.00, 29.6% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
83.2% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features advanced technology, a luxurious feel, and impressive performance, making it a standout option in the full-size luxury sedan segment.
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 179 currently listed for sale near Philadelphia, PA and an average price of $60,022.00, 29.6% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
83.2% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features advanced technology, a luxurious feel, and impressive performance, making it a standout option in the full-size luxury sedan segment.
Why it stands out
The 2021 Mercedes-Benz S-Class sets itself apart as a top-tier luxury sedan with cutting-edge technology and outstanding performance. It is offered in two configurations: the S500, powered by a 3.0-liter turbocharged inline-six engine producing 429 horsepower, and the S580, boasting a robust 4.0-liter twin-turbo V8 engine with 496 horsepower. Both models incorporate EQ Boost mild-hybrid systems for improved efficiency. The car's redesign features a sophisticated infotainment system, dynamic bodywork for enhanced aerodynamics, and the introduction of rear-wheel steering, which improves maneuverability. Inside, the S-Class showcases luxurious materials, with ultra-comfortable seats equipped with massage features and an advanced audio system. Many owners report being thoroughly impressed with the driving experience, though concerns about run-flat tires have been noted. Overall, this sedan delivers a blend of luxury, technology, and performance that appeals to discerning buyers.
Other model years to consider
- Average price: $65,639.00
- Good/great deal percentage: 26.6%
- User rating: 4.5 / 5
- Total listings: 256
- Average price: $25,686.00
- Good/great deal percentage: 27.0%
- User rating: 5 / 5
- Total listings: 248
- Average price: $74,231.00
- Good/great deal percentage: 24.2%
- Accident-free percentage: 88.8%
- Total listings: 260
This analysis is based on CarGurus' proprietary market data from April 14, 2026, CarGurus experts' opinions, and generative AI.
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Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
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