Used 2021 Mercedes-Benz S-Class for Sale near Allentown, PA
192 results
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 770 currently listed for sale and an average price of $62,379.00, 31.9% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
83.5% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a redesigned infotainment system, advanced safety features, and powerful engine options that include a mild-hybrid system for enhanced performance.
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 770 currently listed for sale and an average price of $62,379.00, 31.9% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
83.5% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a redesigned infotainment system, advanced safety features, and powerful engine options that include a mild-hybrid system for enhanced performance.
Why it stands out
The 2021 Mercedes-Benz S-Class is recognized as a pinnacle of luxury and technology in the full-size sedan segment, boasting a range of impressive capabilities that set it apart from its rivals. Key features include standard all-wheel drive and a choice between two powerful engines: the S500 4Matic with a 3.0-liter turbocharged inline-six engine producing 429 horsepower, and the S580 4Matic with a 4.0-liter twin-turbo V8 that delivers 496 horsepower. Owners are particularly impressed with its luxurious interior, loaded with high-quality materials and advanced tech like a 12.8-inch OLED central touchscreen and augmented-reality head-up display. The S-Class stands out not only for its performance but also for its commitment to safety, featuring a comprehensive suite of driver assistance technologies. While some owners have mentioned concerns about the run-flat tires, the overall driving experience—characterized by exceptional comfort and performance—makes the S-Class a compelling choice for luxury car enthusiasts.
Other model years to consider
- Average price: $80,194.00
- Good/great deal percentage: 30.1%
- User rating: Not available
- Total listings: 1,207
- Average price: $65,659.00
- Good/great deal percentage: 30.9%
- User rating: 4.5 / 5
- Total listings: 1,111
- Average price: $25,999.00
- Good/great deal percentage: 31.9%
- User rating: 4.95 / 5
- Total listings: 947
This analysis is based on CarGurus' proprietary market data from June 1, 2026, CarGurus experts' opinions, and generative AI.
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Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
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