Used Mercedes-Benz S-Class S 580 Sedan 4MATIC for SaleNationwide
170 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 24,030
- Stock #:
- 034519-AC
- VIN:
- W1K6G7GB6MA034519
New arrival
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
24,030 mi
Houston, TX
Good Deal
$61,220
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Graphite Gray Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 55,048
- Stock #:
- BMA024233
- VIN:
- W1K6G7GB4MA024233
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
55,048 mi
Plano, TX
Great Deal
$50,225
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black Nappa
- Transmission:
- 9-Speed Automatic
- Mileage:
- 54,628
- Stock #:
- A037163
- VIN:
- W1K6G7GB8MA037163
New arrival
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
54,628 mi
Tamarac, FL
Good Deal
$55,450
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- 9-Speed Automatic
- Mileage:
- 58,987
- Stock #:
- MA047653
- VIN:
- W1K6G7GB9MA047653
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
58,987 mi
Alpharetta, GA
Fair Deal
$55,097
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Gray
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 9-Speed Automatic
- Mileage:
- 38,516
- Stock #:
- DM231
- VIN:
- W1K6G7GB0MA052711
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
38,516 mi
Denver, CO
Good Deal
$58,990
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 25,360
- Stock #:
- I32635
- VIN:
- W1K6G7GB9MA053548
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
25,360 mi
Columbus, OH
Good Deal
$60,238
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 70,779
- Stock #:
- 6079
- VIN:
- W1K6G7GB1MA055844
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
70,779 mi
Clearwater, FL
Fair Deal
$52,809
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 37,259
- Stock #:
- 024313
- VIN:
- W1K6G7GB2MA024313
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
37,259 mi
Marietta, GA
Good Deal
$58,531
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- designo Diamond White Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Macchiato/Magma Gray
- Transmission:
- 9-Speed Automatic
- Mileage:
- 31,926
- Stock #:
- 36MA037563T1
- VIN:
- W1K6G7GB2MA037563
New arrival
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
31,926 mi
Ft Mitchell, KY
Fair Deal
$65,303
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Graphite Gray
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Exclusive Silver Gray/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 32,317
- Stock #:
- 025047F01
- VIN:
- W1K6G7GB1MA025047
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
32,317 mi
Ewing, NJ
Great Deal
$53,889
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black Nappa
- Transmission:
- 9-Speed Automatic
- Mileage:
- 26,854
- Stock #:
- E231651
- VIN:
- W1K6G7GB0MA033950
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
26,854 mi
Santa Fe, NM
Great Deal
$61,387
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Anthracite Blue
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Porcelain/Espresso Brown
- Transmission:
- Automatic
- Mileage:
- 35,174
- Stock #:
- T81977A
- VIN:
- W1K6G7GB9MA051136
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
35,174 mi
Merriam, KS
Good Deal
$60,251
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Macchiato/Magma Gray
- Transmission:
- 9-Speed Automatic
- Mileage:
- 39,863
- Stock #:
- MA042471
- VIN:
- W1K6G7GB0MA042471
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
39,863 mi
Midland, TX
Great Deal
$54,954
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Obsidian Black metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray (Macchiato/Magma Grey)
- Transmission:
- Automatic
- Mileage:
- 53,664
- Stock #:
- 035033
- VIN:
- W1K6G7GB7MA035033
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
53,664 mi
Oxford, CT
Fair Deal
$55,699
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Obsidian Black Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 38,908
- Stock #:
- D1494
- VIN:
- W1K6G7GB7MA061681
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
38,908 mi
Lugoff, SC
Fair Deal
$63,555
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 61,426
- Stock #:
- 028949
- VIN:
- W1K6G7GB1MA028949
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
61,426 mi
Springfield, IL
Fair Deal
$51,373
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 46,429
- Stock #:
- NN056588
- VIN:
- W1K6G7GB3MA056588
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
46,429 mi
Union, NJ
Fair Deal
$58,589
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 20,542
- Stock #:
- 5MC6129
- VIN:
- W1K6G7GB4MA045051
New arrival
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
20,542 mi
Farmington, UT
Great Deal
$61,940
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 55,288
- Stock #:
- SX00476
- VIN:
- W1K6G7GB6MA028817
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
55,288 mi
Stephenville, TX
Fair Deal
$54,775
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 49,703
- Stock #:
- UM8257
- VIN:
- W1K6G7GB2MA057389
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
49,703 mi
Westmont, IL
Fair Deal
$58,358
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 41,452
- Stock #:
- Y14751
- VIN:
- W1K6G7GB2MA054458
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
41,452 mi
Yorktown, VA
Great Deal
$55,674
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Red
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Macchiato/Magma Gray
- Transmission:
- 9-Speed Automatic
- Mileage:
- 32,806
- Stock #:
- BP3308A
- VIN:
- W1K6G7GBXMA049220
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
32,806 mi
Mt Pleasant, SC
Good Deal
$61,788
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 29,448
- Stock #:
- C270027A
- VIN:
- W1K6G7GB4MA044031
Price drop
-$2,500
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
29,448 mi
West Caldwell, NJ
Good Deal
$63,493
$60,993
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 63,409
- Stock #:
- D5798L
- VIN:
- W1K6G7GB0MA039540
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
63,409 mi
Dublin, OH
Fair Deal
$54,385
Overview
The Mercedes-Benz S-Class S 580 4MATIC Sedan AWD is part of a generation that was introduced for the 2021 model year. This big luxury sedan boasts twin-turbocharged V8 power with a mild-hybrid system, and slots under the ultra-luxury Maybach versions of the S-Class. It’s a great car for those with chauffeurs, since the upscale and comfortable cabin can be upgraded with amenities such as pop-out tables and massaging rear seats with pillows and leg rests. Consider the Audi A7 and Genesis G80 as well if you’re shopping for the Mercedes-Benz S-Class S 580 4MATIC Sedan AWD.
Key Features
- 4.0-liter twin-turbocharged V8 engine
- All-wheel drive
- Sedan body style
- Available Executive Rear Seat package
Pricing Details
The 2023 Mercedes-Benz S-Class S 580 4MATIC Sedan AWD has an MSRP of $124,000. The S-Class was fully redesigned for 2021, which is when this trim was introduced, and had an MSRP of $116,300. Used examples on CarGurus range from $39,375.00 to $89,000.00 with an average price of $57,552.75.
Specifications
Performance
Engine
4.0-liter twin-turbocharged V8 engine
Transmission
Nine-speed automatic transmission
Drivetrain
All-wheel drive
Horsepower/Torque
496 hp/516 lb-ft
0-60 mph
4.0 seconds (estimated)
MPG
18 mpg city, 27 highway, 21 combined
Curb weight
4,762 pounds
Dimensions
wheelbase
126.6 inches
length
208.2 inches
width
76.9 inches
height
59.2 inches
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
FAQs
How much does the Mercedes-Benz S-Class S 580 Sedan 4MATIC cost?
The average Mercedes-Benz S-Class S 580 Sedan 4MATIC costs about $57,602.95. The average price has decreased by -7.8% since last year. The 170 for sale on CarGurus range from $39,375 to $89,000 in price.
How many Mercedes-Benz S-Class S 580 Sedan 4MATIC vehicles have no reported accidents or damage?
127 out of 170 for sale have no reported accidents or damage.
What is the fuel economy of the Mercedes-Benz S-Class S 580 Sedan 4MATIC?
Depending on the engine and options, the Mercedes-Benz S-Class S 580 Sedan 4MATIC gets between 20 and 20 MPG/MPGe.
What fuel types are available?
Gasoline engines are available.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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