2021 Mercedes-Benz GLS vs 2021 Honda Odyssey

The 2021 Mercedes-Benz GLS, a continuation of the third generation introduced in 2020, was a luxurious SUV that offered a blend of style and practicality. Originally known as the GL-Class, the GLS evolved to cater to families seeking a lavish alternative to the likes of the Navigator and Escalade. Despite its size, the GLS appeared more refined and less bulky than its predecessors, thanks to softened angles and clever design elements. Inside, the GLS boasted a futuristic cabin dominated by a massive digital screen, emphasizing its tech-centric approach. Available in three trims—GLS 450, GLS 580, and the high-performance AMG GLS 63—the GLS offered a range of features, from remote keyless entry and heated front seats to advanced sound systems and optional luxury packages.

In contrast, the 2021 Honda Odyssey maintained a familiar design with subtle updates to modernize its appearance. The refreshed grille, front bumper, and LED headlights gave it a contemporary look, while new wheel designs added a touch of sophistication. The Odyssey was available in five trims: LX, EX, EX-L, Touring, and Elite, with prices ranging from $31,790 to $47,820. The Elite trim, which we tested, featured perforated leather upholstery, ambient lighting, and improved seating materials, elevating its interior to a more upscale level. The Odyssey's design updates, combined with its practical features, aimed to position it as a premium choice among minivans.

The 2021 Mercedes-Benz GLS offered a range of powerful engine options. The entry-level GLS 450 was equipped with a twin-turbocharged 3.0-liter inline-six engine, producing 362 horsepower and 369 pound-feet of torque. The GLS 580 featured a more robust twin-turbocharged 4.0-liter V8, delivering 483 hp and 516 lb-ft. Both models utilized a nine-speed automatic transmission and Mercedes' 4MATIC all-wheel-drive system. The AMG GLS 63, our test model, boasted a hand-crafted 4.0-liter twin-turbo V8 engine, generating an impressive 603 hp and 627 lb-ft of torque. This powerhouse enabled the GLS 63 to accelerate from zero to 60 mph in just 4.1 seconds, with a top speed of 174 mph. The GLS's adaptive air suspension and multiple drive modes provided a smooth and dynamic driving experience, making it feel agile despite its size.

The 2021 Honda Odyssey, powered by a 3.5-liter V6 engine paired with a ten-speed automatic transmission, delivered 280 horsepower to the front wheels. While lacking all-wheel drive, the Odyssey's drivetrain offered smooth and effortless power delivery. The V6 engine featured variable cylinder management for improved fuel efficiency, achieving an EPA-estimated 22 mpg in combined driving. The Odyssey's ride and handling were enjoyable, with well-weighted steering and firm yet comfortable suspension. However, the brakes showed signs of fade under heavy use, indicating a need for improvement. Despite this, the Odyssey remained a pleasure to drive, offering a balanced and responsive experience.

The 2021 Mercedes-Benz GLS provided ample interior space with three rows of seating, accommodating up to seven passengers. The first and second rows offered generous headroom and legroom, while the third row was suitable for adults. The GLS excelled in cargo space, offering 17.4 cubic feet behind the third row, expanding to 42.7 cubic feet with the third row folded, and a total of 87.4 cubic feet with both rear rows down. The power-folding third row and numerous storage compartments added to its practicality.

The 2021 Honda Odyssey excelled in interior functionality, featuring logical controls and abundant storage. The Magic Slide second-row seats allowed for versatile configurations, enhancing passenger comfort and access to the third row. The Odyssey offered 32.8 cubic feet of cargo space behind the third row, expanding to 88.8 cubic feet with the third row folded, and a maximum of 144.9 cubic feet with the second-row seats removed. While removing the second-row seats was cumbersome, the Odyssey's overall interior space and flexibility made it a standout choice for families.

The 2021 Mercedes-Benz GLS came equipped with the MBUX infotainment system, featuring a large touchscreen and voice-control capabilities. The system supported Apple CarPlay and Android Auto, though a USB-C cable was required for connectivity. The digital dash extended to the instrument panel, offering customizable displays controlled via touch-sensitive pads on the steering wheel. The MBUX system's learning curve was offset by its comprehensive features and user-friendly interface.

The 2021 Honda Odyssey, starting with the EX trim, featured an 8-inch touchscreen infotainment system with Apple CarPlay, Android Auto, and various connectivity options. Touring and Elite trims added navigation, WiFi capability, and a rear-seat entertainment system. HondaLink subscription services offered additional features, including remote operation and concierge services. Despite its extensive technology suite, the Odyssey's lack of a tuning knob and less intuitive voice-recognition system were notable drawbacks.

The 2021 Mercedes-Benz GLS offered a comprehensive suite of standard safety features, including Active Brake Assist, blind-spot monitoring, and a surround-view camera system. Optional safety technologies included lane-keep assist, adaptive cruise control, and stop-and-go cruise control. The GLS's robust safety features provided peace of mind for drivers and passengers alike.

The 2021 Honda Odyssey improved its safety offerings with the standard inclusion of Honda Sensing across all trims. This suite of advanced driving assistance systems included adaptive cruise control with low-speed follow, pedestrian braking, and road-sign recognition. The Odyssey's structural integrity and safety ratings from the IIHS and NHTSA further reinforced its reputation as a safe family vehicle.