Used 2022 Lexus RX for Sale near Anderson, SC

232 results

Anderson, SC

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2022 Lexus RX

350 FWD

57,847 miles

$34,987

Good Deal

Conyers, GA

98 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black (Caviar)
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Birch
Transmission:: 8-Speed Automatic
Mileage:: 57,847
Stock number:: P6931
VIN:: 2T2AZMAAXNC226211

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2022 Lexus RX

350 FWD

50,582 miles

$39,998

Fair Deal

Certified Pre-Owned

Greenville, SC

28 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Eminent White Pearl
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Glazed Caramel
Transmission:: 8-Speed Automatic
Mileage:: 50,582
Stock number:: ANC248207
VIN:: 2T2HZMAAXNC248207

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2021 Lexus RX

350 FWD

35,435 miles

$39,998

Fair Deal

Certified Pre-Owned

Greenville, SC

28 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black (Caviar)
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: White (Parchment)
Transmission:: 8-Speed Automatic
Mileage:: 35,435
Stock number:: AMC190974
VIN:: 2T2HZMAA5MC190974

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2022 Lexus RX

350 FWD

15,567 miles

$45,513

Good Deal

Certified Pre-Owned

Augusta, GA

76 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: White
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Mileage:: 15,567
Stock number:: LP8734
VIN:: 2T2HZMAA2NC229814

2023 Lexus RX

350 Luxury AWD

44,987 miles

$48,951

Good Deal

Columbia, SC

91 mi away

Year:: 2023
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 275 hp 2.4L I4
Exterior color:: Black (Caviar)
Combined gas mileage:: 24 MPG
Fuel type:: Gasoline
Interior color:: Black w/Black Open Pore
Transmission:: Automatic
Mileage:: 44,987
Stock number:: PC006042
VIN:: 2T2BAMCA4PC006042

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2023 Lexus RX

350 FWD

22,298 miles

$43,998

Good Deal

Duluth, GA

91 mi away

Year:: 2023
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 275 hp 2.4L I4
Exterior color:: Silver
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Brown (Beige)
Transmission:: 8-Speed Automatic
Mileage:: 22,298
Stock number:: 013617
VIN:: 2T2BAMBA7PC013617

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2023 Lexus RX

350 FWD

42,817 miles

$40,920

Good Deal

Buford, GA

83 mi away

Year:: 2023
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 275 hp 2.4L I4
Exterior color:: Gray
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 8-Speed Automatic
Mileage:: 42,817
Stock number:: PC019236
VIN:: 2T2BAMBA3PC019236

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2023 Lexus RX

350 Luxury FWD

59,883 miles

$42,597

Great Deal

Store transfer to Greenville, SC

1,380 mi away Price includes $1,599 shipping Price includes $1,599 shipping

Year:: 2023
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 275 hp 2.4L I4
Exterior color:: White
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 59,883
Stock number:: 27400820
VIN:: 2T2BAMBA1PC006985

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2022 Lexus RX

350 F Sport Handling AWD

54,484 miles

$40,998

Great Deal

Columbia, SC

91 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 54,484
Stock number:: 27190672
VIN:: 2T2YZMDA1NC321556

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2021 Lexus RX

350 FWD

30,047 miles

$38,597

Good Deal

Store transfer to Greenville, SC

1,392 mi away Price includes $1,599 shipping Price includes $1,599 shipping

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Brown (Tan)
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Brown (TAN)
Transmission:: Automatic
Mileage:: 30,047
Stock number:: 27402680
VIN:: 2T2HZMAA8MC188376

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2021 Lexus RX

350L AWD

43,230 miles

$36,888

Great Deal

Augusta, GA

76 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 290 hp 3.5L V6
Exterior color:: Black (Caviar)
Combined gas mileage:: 21 MPG
Fuel type:: Gasoline
Interior color:: Birch
Transmission:: Automatic
Mileage:: 43,230
Stock number:: G1522A
VIN:: JTJHZKFA6M2028106

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2021 Lexus RX

350 FWD

101,700 miles

$27,539

Great Deal

Snellville, GA

91 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Silver
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Other
Transmission:: 8-Speed Automatic
Mileage:: 101,700
Stock number:: 188901
VIN:: 2T2AZMAAXMC188901

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2021 Lexus RX

350 FWD

38,937 miles

$39,995

Good Deal

Spartanburg, SC

47 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Atomic Silver
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: White (Parchment w/Matte Bamboo Trim)
Transmission:: 8-Speed Automatic
Mileage:: 38,937
Stock number:: MC204779
VIN:: 2T2HZMAA2MC204779

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2022 Lexus RX

350 FWD

59,960 miles

$38,995

Good Deal

Spartanburg, SC

47 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Blue
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: White (Parchment w/Matte Bamboo Trim)
Transmission:: 8-Speed Automatic
Mileage:: 59,960
Stock number:: NC226547
VIN:: 2T2HZMAA1NC226547

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2022 Lexus RX

350L FWD

36,642 miles

$36,976

Great Deal

Lilburn, GA

95 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 290 hp 3.5L V6
Exterior color:: Black (Caviar)
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 36,642
Stock number:: 25966
VIN:: JTJHZKEA7N2027811

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2023 Lexus RX

350 Premium FWD

26,890 miles

$46,690

Fair Deal

Certified Pre-Owned

Duluth, GA

92 mi away

Year:: 2023
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 275 hp 2.4L I4
Exterior color:: Iridium
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Palo
Transmission:: 8-Speed Automatic
Mileage:: 26,890
Stock number:: G260150A
VIN:: JTJCHMAA9P2008355

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Overview

Reviews

FAQs

CarGurus Analysis: 2022 Lexus RX

Summary

With 2,583 currently listed for sale on CarGurus and an average price of $40,523.30, 35.5% of 2022 Lexus RXs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus RX 4.6 / 5 stars and CarGurus experts gave it an 7.3 / 10.
84.6% of 2022 RX models on CarGurus are accident free.
The 2022 Lexus RX maintained its status as the automaker's best-selling model, offering a comfortable ride and standard advanced safety features, though it featured a design that some found polarizing.

Why it stands out

The 2022 Lexus RX distinguished itself with its exceptional ride quality, providing a smooth and comfortable driving experience that appealed to many consumers. It also prioritized safety by incorporating standard advanced safety features, enhancing peace of mind for drivers and passengers alike. Despite being a carryover model, the RX maintained its position as Lexus’s best-selling vehicle, demonstrating its continued popularity in a competitive market.

Other model years to consider

2021 Lexus RX: This year offers $35,808.26 average price, 33% good/great deals, 4.7/5 user rating, 7.8/10 expert rating, 1,840 listings.
2020 Lexus RX: This year offers $33,383.04 average price, 32% good/great deals, 4.8/5 user rating, 8.2/10 expert rating, 1,248 listings.
2023 Lexus RX: This year offers $47,685.72 average price, 36% good/great deals, 4.6/5 user rating, 7.2/10 expert rating, 3,126 listings.

This analysis is based on CarGurus' proprietary market data from December 3, 2025, CarGurus experts' opinions, and generative AI.

4.6 Overall rating

(24 reviews)

Anonymous

5.0

Reviewed a 2022 Lexus RX on Feb 19, 2024

I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!

Uday T

4.0

Reviewed a 2022 Lexus RX on Jun 06, 2023

Great car, drives smooth. Lacks pick up power for a V6

Anonymous

5.0

Reviewed a 2022 Lexus 350 AWD on Jun 06, 2023

No unneeded frills but lots of quality of life items. Love the backup camera and surround view, easily the best one out of all the cars we test drove (GMC, Buick, Ford, Nissan). Suspension is solid, corners well, and plenty of power.

Anonymous

4.0

Reviewed a 2022 Lexus 350 FWD on Feb 08, 2023

Car is wonderful except for the gas mileage. Pretty, nice size, comfortable, good safety features.

Anonymous

5.0

Reviewed a 2022 Lexus 350 FWD on Oct 03, 2022

An excellent car which is loaded with features and fun to drive. It is smooth and has a very quiet cabin. Also very luxurious materials in the cabin and fine leather seats,

2022 Lexus RX FAQs

How much does the 2022 Lexus RX cost in Anderson, SC?

The average 2022 Lexus RX costs about $40,554.05. The average price has decreased by -4.5% since last year. The 174 for sale near Anderson, SC on CarGurus, range from $27,680 to $56,512 in price.

Is the 2022 Lexus RX a good car?

CarGurus experts gave the 2022 Lexus RX an overall rating of 7.3/10 and 2022 Lexus RX owners have rated the vehicle a 4.6/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Lexus RX vehicles in Anderson, SC have no reported accidents or damage?

174 out of 174 for sale near Anderson, SC have no reported accidents or damage.

Is the 2022 Lexus RX safe?

CarGurus experts gave the 2022 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2022 Lexus RX?

Depending on the engine and options, the 2022 Lexus RX gets between 21 and 25 MPG (or MPGe).

What fuel types are available?

Gasoline engines are available.

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