Used 2022 Lexus RX for Sale near Spartanburg, SC

211 results

Spartanburg, SC

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2023 Lexus RX

350 Luxury AWD

79,030 miles

$47,999

Fair Deal

Hendersonville, NC

38 mi away

Year:: 2023
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 275 hp 2.4L I4
Exterior color:: Iridium
Combined gas mileage:: 24 MPG
Fuel type:: Gasoline
Interior color:: Peppercorn
Transmission:: Automatic
Mileage:: 79,030
Stock number:: P12766
VIN:: 2T2BAMCA3PC015296

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2022 Lexus RX

350 AWD

47,978 miles

$41,619

Fair Deal

Charlotte, NC

69 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black (Caviar)
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 47,978
Stock number:: TB1163A
VIN:: 2T2HZMDA8NC353436

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2022 Lexus RX

350 FWD

54,153 miles

$37,007

Good Deal

Lowell, NC

51 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Mica
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: White (Parchment)
Transmission:: 8-Speed Automatic
Mileage:: 54,153
Stock number:: PV23479
VIN:: 2T2AZMAA4NC223479

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2022 Lexus RX

350 FWD

27,928 miles

$42,995

Great Deal

Spartanburg, SC

5 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Nightfall Mica
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Black (Charcoal)
Transmission:: 8-Speed Automatic
Mileage:: 27,928
Stock number:: NC225891
VIN:: 2T2HZMAA0NC225891

2022 Lexus RX

350 FWD

59,960 miles

$37,995

Great Deal

Spartanburg, SC

5 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Blue
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: White (Parchment w/Matte Bamboo Trim)
Transmission:: 8-Speed Automatic
Mileage:: 59,960
Stock number:: NC226547
VIN:: 2T2HZMAA1NC226547

2021 Lexus RX

350 FWD

37,970 miles

$37,197

Good Deal

Store transfer to Greenville, SC

284 mi away Price includes $199 shipping Price includes $199 shipping

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Green
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Brown (TAN)
Transmission:: Automatic
Mileage:: 37,970
Stock number:: 28144060
VIN:: 2T2AZMAA0MC218875

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2022 Lexus RX

350L FWD

54,375 miles

$39,993

Good Deal

Concord, NC

75 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 290 hp 3.5L V6
Exterior color:: Cloudburst Gray
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Birch
Transmission:: Automatic
Mileage:: 54,375
Stock number:: X211287
VIN:: JTJHZKEA9N2024747

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2022 Lexus RX

350 AWD

25,227 miles

$40,925

Good Deal

Fort Mill, SC

56 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Nebula Gray Pearl
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 25,227
Stock number:: P11463
VIN:: 2T2HZMDA3NC345843

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2023 Lexus RX

350 Premium FWD

34,642 miles

$43,895

Good Deal

Matthews, NC

70 mi away

Year:: 2023
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 275 hp 2.4L I4
Exterior color:: Nebula Gray Pearl
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Palomino w/Ash Bamboo
Transmission:: 8-Speed Automatic
Mileage:: 34,642
Stock number:: PC020584P
VIN:: 2T2BAMBA9PC020584

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2021 Lexus RX

350L AWD

43,230 miles

$36,888

Great Deal

Augusta, GA

99 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 290 hp 3.5L V6
Exterior color:: Black (Caviar)
Combined gas mileage:: 21 MPG
Fuel type:: Gasoline
Interior color:: Birch
Transmission:: Automatic
Mileage:: 43,230
Stock number:: G1522A
VIN:: JTJHZKFA6M2028106

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2022 Lexus RX

350 FWD

52,479 miles

$36,997

Great Deal

Store transfer to Greenville, SC

2,065 mi away Price includes $1,999 shipping Price includes $1,999 shipping

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Gray
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 8-Speed Automatic Overdrive
Mileage:: 52,479
Stock number:: 28142708
VIN:: 2T2AZMAA5NC233566

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2021 Lexus RX

350 AWD

102,075 miles

$29,437

Fair Deal

Arden, NC

51 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Eminent White Pearl
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Birch
Transmission:: 8-Speed Automatic
Mileage:: 102,075
Stock number:: T60833
VIN:: 2T2HZMDA4MC260833

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2023 Lexus RX

350 Premium AWD

17,690 miles

$46,300

Good Deal

Lenoir, NC

71 mi away

Year:: 2023
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 275 hp 2.4L I4
Exterior color:: Red (COPPER CREST)
Fuel type:: Gasoline
Transmission:: 6-Speed Automatic
Mileage:: 17,690
Stock number:: J03774
VIN:: 2T2BAMCA8PC003774

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2022 Lexus RX

350 F Sport Handling AWD

29,993 miles

$43,475

Good Deal

Concord, NC

80 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Transmission:: Automatic
Mileage:: 29,993
Stock number:: 3N4978A
VIN:: 2T2YZMDA1NC354055

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2022 Lexus RX

350L AWD

56,269 miles

$40,397

Good Deal

Store transfer to Greenville, SC

871 mi away Price includes $1,399 shipping Price includes $1,399 shipping

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 290 hp 3.5L V6
Exterior color:: Gray
Combined gas mileage:: 21 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 56,269
Stock number:: 27993678
VIN:: JTJHZKFA1N2040892

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2022 Lexus RX

350 FWD

94,544 miles

$30,895

Good Deal

Charlotte, NC

60 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Nebula Gray Pearl
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 94,544
Stock number:: PC6103A
VIN:: 2T2HZMAAXNC237949

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2023 Lexus RX

350 Premium+ AWD

33,323 miles

$44,496

Great Deal

Charlotte, NC

67 mi away

Year:: 2023
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 275 hp 2.4L I4
Exterior color:: Silver
Combined gas mileage:: 24 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 33,323
Stock number:: PPC010356
VIN:: 2T2BAMCA3PC010356

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2022 Lexus RX

350 AWD

25,227 miles

$40,925

Good Deal

Fort Mill, SC

56 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Nebula Gray Pearl
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 25,227
Stock number:: P11463
VIN:: 2T2HZMDA3NC345843

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Overview

Reviews

FAQs

CarGurus Analysis: 2022 Lexus RX

Summary

With 2,526 currently listed for sale on CarGurus and an average price of $40,414.60, 35.6% of 2022 Lexus RXs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus RX 4.6 / 5 stars and CarGurus experts gave it an 7.3 / 10.
84.2% of 2022 RX models on CarGurus are accident free.
The 2022 Lexus RX combined a smooth ride quality with standard advanced safety features, solidifying its status as the brand's best-selling model despite its aging design.

Why it stands out

The 2022 Lexus RX stood out for its exceptional ride quality, ensuring a comfortable driving experience that many owners appreciated. It also included standard advanced safety features, reflecting Lexus's commitment to driver and passenger safety. Despite its dated design and some ergonomic considerations, the RX maintained strong sales figures, showcasing its enduring appeal in the luxury SUV market.

Other model years to consider

2020 Lexus RX: This year offers $33,379.27 average price, 33% good/great deals, 4.8/5 user rating, 8.2/10 expert rating, 1,269 listings.
2021 Lexus RX: This year offers $35,773.39 average price, 32% good/great deals, 4.7/5 user rating, 7.8/10 expert rating, 1,829 listings.
2023 Lexus RX: This year offers $47,405.06 average price, 37% good/great deals, 4.6/5 user rating, 7.2/10 expert rating, 3,056 listings.

This analysis is based on CarGurus' proprietary market data from December 16, 2025, CarGurus experts' opinions, and generative AI.

4.6 Overall rating

(24 reviews)

Anonymous

5.0

Reviewed a 2022 Lexus RX on Feb 19, 2024

I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!

Uday T

4.0

Reviewed a 2022 Lexus RX on Jun 06, 2023

Great car, drives smooth. Lacks pick up power for a V6

Anonymous

5.0

Reviewed a 2022 Lexus 350 AWD on Jun 06, 2023

No unneeded frills but lots of quality of life items. Love the backup camera and surround view, easily the best one out of all the cars we test drove (GMC, Buick, Ford, Nissan). Suspension is solid, corners well, and plenty of power.

Anonymous

4.0

Reviewed a 2022 Lexus 350 FWD on Feb 08, 2023

Car is wonderful except for the gas mileage. Pretty, nice size, comfortable, good safety features.

Anonymous

5.0

Reviewed a 2022 Lexus 350 FWD on Oct 03, 2022

An excellent car which is loaded with features and fun to drive. It is smooth and has a very quiet cabin. Also very luxurious materials in the cabin and fine leather seats,

2022 Lexus RX FAQs

How much does the 2022 Lexus RX cost in Spartanburg, SC?

The average 2022 Lexus RX costs about $39,904.35. The average price has decreased by -4.9% since last year. The 169 for sale near Spartanburg, SC on CarGurus, range from $26,665 to $56,998 in price.

Is the 2022 Lexus RX a good car?

CarGurus experts gave the 2022 Lexus RX an overall rating of 7.3/10 and 2022 Lexus RX owners have rated the vehicle a 4.6/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Lexus RX vehicles in Spartanburg, SC have no reported accidents or damage?

169 out of 169 for sale near Spartanburg, SC have no reported accidents or damage.

Is the 2022 Lexus RX safe?

CarGurus experts gave the 2022 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2022 Lexus RX?

Depending on the engine and options, the 2022 Lexus RX gets between 21 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

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