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Used 2022 Lexus RX for Sale near Columbia, SC

221 results
Columbia, SC
2021 Lexus RX 350 F Sport Handling AWD Brandon Reeves Auto World

2021 Lexus RX

350 F Sport Handling AWD

78,501 miles

$36,085

Fair Deal
Monroe, NC
73 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Ultra White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
78,501
Stock number:
24498
VIN:
2T2YZMDA9MC275747

Sponsored

2023 Lexus RX 350 Premium FWD

2023 Lexus RX

350 Premium FWD

21,879 miles

$45,990

Fair Deal
Charlotte, NC
82 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Nori Green Pearl
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Macadamia
Transmission:
Automatic
Mileage:
21,879
Stock number:
P2006847
VIN:
JTJCHMAA9P2006847

Sponsored

2023 Lexus RX 350 FWD

2023 Lexus RX

350 FWD

59,657 miles

$41,621

Good Deal
Certified Pre-Owned
Charlotte, NC
81 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Iridium
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Macadamia
Transmission:
Automatic
Mileage:
59,657
Stock number:
T16893A
VIN:
2T2BAMBA4PC008908

Sponsored

2023 Lexus RX 350 Premium AWD

2023 Lexus RX

350 Premium AWD

9,008 miles

$48,410

Good Deal
Columbia, SC
8 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Eminent White Pearl
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Palomino W/Ash Bamboo
Transmission:
8-Speed Automatic
Mileage:
9,008
Stock number:
BA2770
VIN:
2T2BAMCA7PC019593

2022 Lexus RX 350 F Sport Handling AWD

2022 Lexus RX

350 F Sport Handling AWD

29,993 miles

$41,975

Great Deal
Concord, NC
97 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
29,993
Stock number:
3N4978A
VIN:
2T2YZMDA1NC354055

2022 Lexus RX 350 FWD

2022 Lexus RX

350 FWD

42,235 miles

$37,483

Great Deal
Sumter, SC
40 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
42,235
Stock number:
P9915
VIN:
2T2AZMAA1NC228512

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2022 Lexus RX

350 FWD

59,729 miles

$33,796

Great Deal
Charlotte, NC
83 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Brown (Tan)
Transmission:
Automatic
Mileage:
59,729
Stock number:
CNC232165
VIN:
2T2AZMAA4NC232165

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2021 Lexus RX

350 FWD

30,375 miles

$37,980

Good Deal
Lexington, SC
9 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Pewter
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
30,375
Stock number:
L4526
VIN:
2T2HZMAA7MC217446

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2021 Lexus RX

350 FWD

61,559 miles

$32,999

Good Deal
Anderson, SC
95 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Pewter
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
61,559
Stock number:
12474
VIN:
2T2AZMAA6MC201871

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2022 Lexus RX

350 F Sport Handling AWD

40,843 miles

$43,995

Good Deal
Spartanburg, SC
85 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black w/Scored Aluminum Trim
Transmission:
8-Speed Automatic
Mileage:
40,843
Stock number:
NC350367
VIN:
2T2YZMDA0NC350367

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2021 Lexus RX

350 FWD

67,490 miles

$32,998

Great Deal
Greenville, SC
92 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
Automatic
Mileage:
67,490
Stock number:
28103054
VIN:
2T2AZMAA0MC195775

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2023 Lexus RX

350 Premium+ AWD

33,323 miles

$42,987

Great Deal
Charlotte, NC
83 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Silver
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
33,323
Stock number:
PPC010356
VIN:
2T2BAMCA3PC010356

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2022 Lexus RX

350 FWD

66,677 miles

$35,043

Good Deal
Charlotte, NC
78 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
66,677
Stock number:
LR23800
VIN:
2T2AZMAA3NC223800

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2021 Lexus RX

350L FWD

139,434 miles

$26,182

Fair Deal
Charlotte, NC
94 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Eminent White Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Glazed Caramel
Transmission:
Automatic
Mileage:
139,434
Stock number:
T20537AA
VIN:
JTJHZKEA3M2019140

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2022 Lexus RX

350 FWD

28,675 miles

$35,996

Great Deal
Pineville, NC
74 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
28,675
Stock number:
GNC221503
VIN:
2T2AZMAA9NC221503

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2023 Lexus RX

350 FWD

24,419 miles

$41,247

Great Deal
Store transfer to Columbia, SC
464 mi away • Price includes $249 shipping Price includes $249 shipping
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
White
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
24,419
Stock number:
28395877
VIN:
2T2BAMBA1PC010079

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2022 Lexus RX

350 FWD

59,960 miles

$37,995

Great Deal
Spartanburg, SC
85 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Blue
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment w/Matte Bamboo Trim)
Transmission:
8-Speed Automatic
Mileage:
59,960
Stock number:
NC226547
VIN:
2T2HZMAA1NC226547

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2021 Lexus RX

350 AWD

62,452 miles

$33,640

Great Deal
Summerville, SC
85 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
8-Speed Automatic
Mileage:
62,452
Stock number:
F23806
VIN:
2T2HZMDAXMC278348

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2022 Lexus RX

350 FWD

42,718 miles

$38,750

Good Deal
Greer, SC
94 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Matador Red
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
42,718
Stock number:
250896A
VIN:
2T2HZMAA7NC245345

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2022 Lexus RX

350 FWD

99,303 miles

$32,698

Fair Deal
Columbia, SC
9 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black/Birch
Transmission:
8-Speed Automatic
Mileage:
99,303
Stock number:
CNN233552
VIN:
2T2HZMAA7NC233552

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2022
  5. / South Carolina
  6. / Columbia
Overview
Reviews
FAQs

CarGurus Analysis: 2022 Lexus RX

Picture of 2022 Lexus RX ## Summary - With 2,069 currently listed for sale on CarGurus and an **average price of $39,701.00**, 31.5% of 2022 Lexus RX models for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2022 Lexus RX 4.58 / 5 stars and CarGurus experts gave it an 7.33 / 10. - **84.4% of 2022 Lexus RX models on CarGurus are accident free**. - The 2022 Lexus RX maintains its reputation as a best-seller due to its attractive design, luxury amenities, and driving comfort, bolstered by tried-and-true reliability. ## Why it stands out The 2022 Lexus RX distinguishes itself in the crowded midsize luxury crossover segment with its blend of style, comfort, and advanced technology. Although it doesn’t excel in performance, it continues to attract buyers with a modern exterior that features distinct character lines and sporty accents, making it visually appealing compared to competitors like the Audi Q5 and BMW X5. This iteration builds on minimal changes from previous years, ensuring familiar luxury while incorporating new color options. Inside, the RX exudes a high-quality feel with multiple interior configurations, although some users have noted that the ergonomics could use improvement. The ride quality is highly praised for its smoothness, making it a great choice for long drives, while the quiet cabin adds to the overall comfort. ## Other model years to consider - **[2023 Lexus RX](https://www.cargurus.com/Cars/l-Used-2023-Lexus-RX-c32334)** - Average price: $46,857.00 - Good/great deal percentage: 32.0% - User rating: 4.62 / 5 - Total listings: 2,455 - **[2021 Lexus RX](https://www.cargurus.com/Cars/l-Used-2021-Lexus-RX-c30886)** - Average price: $35,529.00 - Good/great deal percentage: 33.1% - User rating: 4.73 / 5 - Total listings: 1,342 - **[2020 Lexus RX](https://www.cargurus.com/Cars/l-Used-2020-Lexus-RX-c29337)** - Average price: $32,768.00 - Good/great deal percentage: 34.6% - User rating: 4.77 / 5 - Total listings: 1,105 This analysis is based on CarGurus' proprietary market data from March 2, 2026, CarGurus experts' opinions, and generative AI.

4.6 Overall rating

(24 reviews)
Uday T
4.0
Reviewed a 2022 Lexus RX on Jun 06, 2023

Great car, drives smooth. Lacks pick up power for a V6

Anonymous
5.0
Reviewed a 2022 Lexus RX on Feb 19, 2024

I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!

Anonymous
5.0
Reviewed a 2022 Lexus 350 AWD on Jun 06, 2023

No unneeded frills but lots of quality of life items. Love the backup camera and surround view, easily the best one out of all the cars we test drove (GMC, Buick, Ford, Nissan). Suspension is solid, corners well, and plenty of power.

Anonymous
4.0
Reviewed a 2022 Lexus 350 FWD on Feb 08, 2023

Car is wonderful except for the gas mileage. Pretty, nice size, comfortable, good safety features.

Anonymous
5.0
Reviewed a 2022 Lexus 350 FWD on Oct 03, 2022

An excellent car which is loaded with features and fun to drive. It is smooth and has a very quiet cabin. Also very luxurious materials in the cabin and fine leather seats,

2022 Lexus RX FAQs

How much does the 2022 Lexus RX cost in Columbia, SC?

The average 2022 Lexus RX costs about $39,850.94. The average price has decreased by -3.4% since last year. The 157 for sale near Columbia, SC on CarGurus, range from $27,862 to $56,242 in price.

Is the 2022 Lexus RX a good car?

CarGurus experts gave the 2022 Lexus RX an overall rating of 7.3/10 and 2022 Lexus RX owners have rated the vehicle a 4.6/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Lexus RX vehicles in Columbia, SC have no reported accidents or damage?

157 out of 157 for sale near Columbia, SC have no reported accidents or damage.

Is the 2022 Lexus RX safe?

CarGurus experts gave the 2022 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2022 Lexus RX?

Depending on the engine and options, the 2022 Lexus RX gets between 21 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

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