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Used 2022 Lexus RX for Sale near South Carolina

217 results
Columbia, SC
2021 Lexus RX 350 FWD Escude Nissan of Greer

2021 Lexus RX

350 FWD

44,826 miles

$38,417

Good Deal
Greer, SC
93 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Brown (Moonbeam Beige Metallic)
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
44,826
Stock number:
T196008
VIN:
2T2AZMAA6MC196008

Sponsored

2021 Lexus RX 350 AWD

2021 Lexus RX

350 AWD

60,116 miles

$35,650

Good Deal
Moncks Corner, SC
87 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Obsidian)
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
60,116
Stock number:
11923B
VIN:
JTJHZMDA4M2051639

Sponsored

2021 Lexus RX 350 FWD

2021 Lexus RX

350 FWD

47,764 miles

$35,500

Good Deal
Charlotte, NC
76 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
47,764
Stock number:
P3719
VIN:
2T2HZMAA6MC195374

Sponsored

2022 Lexus RX 350 FWD

2022 Lexus RX

350 FWD

42,235 miles

$37,283

Great Deal
Sumter, SC
40 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
42,235
Stock number:
P9915
VIN:
2T2AZMAA1NC228512

2021 Lexus RX 350 AWD

2021 Lexus RX

350 AWD

49,822 miles

$37,392

Fair Deal
Concord, NC
94 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nori Green Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
Automatic
Mileage:
49,822
Stock number:
XH21757A
VIN:
2T2HZMDA0MC277919

2022 Lexus RX 350 F Sport Handling AWD

2022 Lexus RX

350 F Sport Handling AWD

40,843 miles

$43,995

Good Deal
Spartanburg, SC
85 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black w/Scored Aluminum Trim
Transmission:
8-Speed Automatic
Mileage:
40,843
Stock number:
NC350367
VIN:
2T2YZMDA0NC350367

Preparing for a close up...

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2023 Lexus RX

350 Premium AWD

9,008 miles

$48,410

Good Deal
Columbia, SC
8 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Eminent White Pearl
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Palomino W/Ash Bamboo
Transmission:
8-Speed Automatic
Mileage:
9,008
Stock number:
BA2770
VIN:
2T2BAMCA7PC019593

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2021 Lexus RX

350 F Sport Handling AWD

78,501 miles

$35,497

Fair Deal
Monroe, NC
73 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Ultra White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
78,501
Stock number:
24498
VIN:
2T2YZMDA9MC275747

Preparing for a close up...

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2021 Lexus RX

350 FWD

44,826 miles

$38,417

Good Deal
Greer, SC
93 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Brown (Moonbeam Beige Metallic)
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
44,826
Stock number:
T196008
VIN:
2T2AZMAA6MC196008

Preparing for a close up...

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2022 Lexus RX

350 FWD

28,675 miles

$35,496

Great Deal
Pineville, NC
74 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
28,675
Stock number:
GNC221503
VIN:
2T2AZMAA9NC221503

Preparing for a close up...

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2021 Lexus RX

350 FWD

30,375 miles

$37,980

Good Deal
Lexington, SC
9 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Pewter
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
30,375
Stock number:
L4526
VIN:
2T2HZMAA7MC217446

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 AWD

60,116 miles

$35,650

Good Deal
Moncks Corner, SC
87 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Obsidian)
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
60,116
Stock number:
11923B
VIN:
JTJHZMDA4M2051639

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 FWD

41,391 miles

$39,297

Great Deal
Store transfer to Columbia, SC
521 mi away • Price includes $299 shipping Price includes $299 shipping
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Red
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Brown (TAN)
Transmission:
Automatic
Mileage:
41,391
Stock number:
28282078
VIN:
2T2BAMBA5PC016709

Preparing for a close up...

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2023 Lexus RX

350 Premium FWD

57,513 miles

$42,097

Great Deal
Store transfer to Columbia, SC
899 mi away • Price includes $1,099 shipping Price includes $1,099 shipping
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Silver
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
Automatic
Mileage:
57,513
Stock number:
27911564
VIN:
JTJCHMAA5P2000804

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

42,718 miles

$38,750

Good Deal
Greer, SC
94 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Matador Red
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
42,718
Stock number:
250896A
VIN:
2T2HZMAA7NC245345

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

47,764 miles

$35,500

Good Deal
Charlotte, NC
76 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
47,764
Stock number:
P3719
VIN:
2T2HZMAA6MC195374

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 AWD

62,452 miles

$32,300

Great Deal
Summerville, SC
85 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
8-Speed Automatic
Mileage:
62,452
Stock number:
F23806
VIN:
2T2HZMDAXMC278348

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

59,729 miles

$33,787

Great Deal
Charlotte, NC
83 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Brown (Tan)
Transmission:
Automatic
Mileage:
59,729
Stock number:
CNC232165
VIN:
2T2AZMAA4NC232165

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

66,677 miles

$34,040

Good Deal
Charlotte, NC
78 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
66,677
Stock number:
LR23800
VIN:
2T2AZMAA3NC223800

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

94,241 miles

$28,200

Good Deal
Monroe, NC
75 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
94,241
Stock number:
P4166
VIN:
2T2AZMAA0MC197445

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

49,235 miles

$35,247

Great Deal
Store transfer to Columbia, SC
419 mi away • Price includes $249 shipping Price includes $249 shipping
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
49,235
Stock number:
28067087
VIN:
2T2HZMAA4MC218523

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 AWD

49,822 miles

$37,392

Fair Deal
Concord, NC
94 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nori Green Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
Automatic
Mileage:
49,822
Stock number:
XH21757A
VIN:
2T2HZMDA0MC277919

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2022
  5. / South Carolina
Overview
Reviews
FAQs

CarGurus Analysis: 2022 Lexus RX

Picture of 2022 Lexus RX ## Summary - With 2,087 currently listed for sale on CarGurus and an **average price of $39,873**, 32.2% of 2022 Lexus RX models for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2022 Lexus RX 4.58 / 5 stars. - **84.3% of 2022 RX models on CarGurus are accident free**. - The 2022 Lexus RX maintains its position as a best-seller in the luxury midsize crossover segment thanks to its attractive design, luxurious interior, driving comfort, and reliability. ## Why it stands out The 2022 Lexus RX distinguishes itself with a modern and sporty design that features aggressive character lines and angular cues reminiscent of a boomerang. Available in various trims, including sporty F Sport and three-row L versions, the RX caters to different needs while delivering a high-quality feel inside. This luxury crossover is not just about looks; it's equipped with numerous standard advanced safety features as part of the Lexus Safety System 2.0+, making it a comforting choice for families and safety-conscious drivers alike. Although some users have pointed out limitations in pick-up power and gas mileage, the overall driving experience remains smooth and quiet, ideal for long journeys. With an extensive list of technology features, the RX is appealing for tech-savvy buyers. ## Other model years to consider - **[2021 Lexus RX](https://www.cargurus.com/Cars/l-Used-2021-Lexus-RX-c30886)** - Average price: $35,677.00 - Good/great deal percentage: 33.1% - User rating: 4.73 / 5 - Total listings: 1,350 - **[2020 Lexus RX](https://www.cargurus.com/Cars/l-Used-2020-Lexus-RX-c29337)** - Average price: $33,042.00 - Good/great deal percentage: 34.8% - User rating: 4.77 / 5 - Total listings: 1,100 - **[2023 Lexus RX](https://www.cargurus.com/Cars/l-Used-2023-Lexus-RX-c32334)** - Average price: $46,881.00 - Good/great deal percentage: 32.6% - User rating: 4.62 / 5 - Total listings: 2,497 This analysis is based on CarGurus' proprietary market data from March 9, 2026, CarGurus experts' opinions, and generative AI.

4.6 Overall rating

(24 reviews)
Uday T
4.0
Reviewed a 2022 Lexus RX on Jun 06, 2023

Great car, drives smooth. Lacks pick up power for a V6

Anonymous
5.0
Reviewed a 2022 Lexus RX on Feb 19, 2024

I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!

Anonymous
5.0
Reviewed a 2022 Lexus 350 AWD on Jun 06, 2023

No unneeded frills but lots of quality of life items. Love the backup camera and surround view, easily the best one out of all the cars we test drove (GMC, Buick, Ford, Nissan). Suspension is solid, corners well, and plenty of power.

Anonymous
4.0
Reviewed a 2022 Lexus 350 FWD on Feb 08, 2023

Car is wonderful except for the gas mileage. Pretty, nice size, comfortable, good safety features.

Anonymous
5.0
Reviewed a 2022 Lexus 350 FWD on Oct 03, 2022

An excellent car which is loaded with features and fun to drive. It is smooth and has a very quiet cabin. Also very luxurious materials in the cabin and fine leather seats,

2022 Lexus RX FAQs

How much does the 2022 Lexus RX cost in South Carolina?

The average 2022 Lexus RX costs about $39,873.89. The average price has decreased by -3.2% since last year. The 152 for sale near South Carolina on CarGurus, range from $27,862 to $57,264 in price.

Is the 2022 Lexus RX a good car?

CarGurus experts gave the 2022 Lexus RX an overall rating of 7.3/10 and 2022 Lexus RX owners have rated the vehicle a 4.6/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Lexus RX vehicles in South Carolina have no reported accidents or damage?

152 out of 152 for sale near South Carolina have no reported accidents or damage.

Is the 2022 Lexus RX safe?

CarGurus experts gave the 2022 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2022 Lexus RX?

Depending on the engine and options, the 2022 Lexus RX gets between 21 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

  • 2025 Lexus RX in South Carolina

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  • Lexus RX 350 FWD

  • Lexus RX 350 AWD in South Carolina

  • Lexus RX 350 F Sport AWD

  • Lexus RX 350 F Sport Handling AWD

  • Lexus RX 350L AWD

  • Lexus RX 350L FWD

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  • Lexus RX 350 F Sport Series 3 AWD

  • 2022 Lexus RX in Columbia SC

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  • Lexus RX in South Carolina

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