Used 2022 Lexus RX for Sale near South Carolina

211 results

Columbia, SC

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2021 Lexus RX

350 FWD

94,241 miles

$29,500

Fair Deal

Monroe, NC

75 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black (Caviar)
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: White (Parchment)
Transmission:: 8-Speed Automatic
Mileage:: 94,241
Stock number:: P4166
VIN:: 2T2AZMAA0MC197445

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2022 Lexus RX

350 FWD

53,445 miles

$40,443

Fair Deal

Matthews, NC

77 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black (Caviar)
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 8-Speed Automatic
Mileage:: 53,445
Stock number:: PL48943
VIN:: 2T2HZMAA9NC248943

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2022 Lexus RX

350 FWD

11,271 miles

$47,942

Fair Deal

Certified Pre-Owned

Augusta, GA

69 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Mileage:: 11,271
Stock number:: L35811A
VIN:: 2T2HZMAA8NC231678

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2022 Lexus RX

350 FWD

10,027 miles

$44,897

Good Deal

Store transfer to Columbia, SC

925 mi away Price includes $899 shipping Price includes $899 shipping

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Red
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Brown
Transmission:: Automatic
Mileage:: 10,027
Stock number:: 28326088
VIN:: 2T2HZMAA3NC250719

2021 Lexus RX

350 AWD

50,871 miles

$36,597

Great Deal

Store transfer to Columbia, SC

587 mi away Price includes $599 shipping Price includes $599 shipping

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 50,871
Stock number:: 28156245
VIN:: 2T2HZMDA4MC261660

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2023 Lexus RX

350 Premium FWD

34,642 miles

$43,757

Great Deal

Matthews, NC

79 mi away

Year:: 2023
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 275 hp 2.4L I4
Exterior color:: Nebula Gray Pearl
Combined gas mileage:: 25 MPG
Fuel type:: Gasoline
Interior color:: Palomino w/Ash Bamboo
Transmission:: 8-Speed Automatic
Mileage:: 34,642
Stock number:: PC020584P
VIN:: 2T2BAMBA9PC020584

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2022 Lexus RX

350L FWD

54,375 miles

$39,993

Good Deal

Concord, NC

94 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 290 hp 3.5L V6
Exterior color:: Cloudburst Gray
Combined gas mileage:: 22 MPG
Fuel type:: Gasoline
Interior color:: Birch
Transmission:: Automatic
Mileage:: 54,375
Stock number:: X211287
VIN:: JTJHZKEA9N2024747

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2022 Lexus RX

350 FWD

59,960 miles

$37,995

Good Deal

Spartanburg, SC

85 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Blue
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: White (Parchment w/Matte Bamboo Trim)
Transmission:: 8-Speed Automatic
Mileage:: 59,960
Stock number:: NC226547
VIN:: 2T2HZMAA1NC226547

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2022 Lexus RX

350 FWD

52,479 miles

$36,997

Great Deal

Store transfer to Columbia, SC

2,126 mi away Price includes $1,999 shipping Price includes $1,999 shipping

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Gray
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 8-Speed Automatic Overdrive
Mileage:: 52,479
Stock number:: 28142708
VIN:: 2T2AZMAA5NC233566

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2022 Lexus RX

350 FWD

27,928 miles

$42,995

Good Deal

Spartanburg, SC

85 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Nightfall Mica
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Black (Charcoal)
Transmission:: 8-Speed Automatic
Mileage:: 27,928
Stock number:: NC225891
VIN:: 2T2HZMAA0NC225891

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2021 Lexus RX

350L AWD

43,230 miles

$36,888

Great Deal

Augusta, GA

69 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 290 hp 3.5L V6
Exterior color:: Black (Caviar)
Combined gas mileage:: 21 MPG
Fuel type:: Gasoline
Interior color:: Birch
Transmission:: Automatic
Mileage:: 43,230
Stock number:: G1522A
VIN:: JTJHZKFA6M2028106

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2021 Lexus RX

350 FWD

47,764 miles

$36,500

Good Deal

Charlotte, NC

76 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Black
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: 8-Speed Automatic
Mileage:: 47,764
Stock number:: P3719
VIN:: 2T2HZMAA6MC195374

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2021 Lexus RX

350 FWD

26,560 miles

$37,676

Good Deal

Summerville, SC

85 mi away

Year:: 2021
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Brown (Moonbeam Beige Metallic)
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: White (Parchment)
Transmission:: 8-Speed Automatic
Mileage:: 26,560
Stock number:: 25WG401A
VIN:: 2T2AZMAA9MC215800

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2022 Lexus RX

350 FWD

94,544 miles

$30,895

Good Deal

Charlotte, NC

76 mi away

Year:: 2022
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: Front-Wheel Drive
Engine:: 295 hp 3.5L V6
Exterior color:: Nebula Gray Pearl
Combined gas mileage:: 23 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 94,544
Stock number:: PC6103A
VIN:: 2T2HZMAAXNC237949

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2023 Lexus RX

350 Premium+ AWD

33,323 miles

$44,487

Great Deal

Charlotte, NC

83 mi away

Year:: 2023
Make:: Lexus
Model:: RX
Body type:: SUV / Crossover
Doors:: 4 doors
Drivetrain:: All-Wheel Drive
Engine:: 275 hp 2.4L I4
Exterior color:: Silver
Combined gas mileage:: 24 MPG
Fuel type:: Gasoline
Interior color:: Black
Transmission:: Automatic
Mileage:: 33,323
Stock number:: PPC010356
VIN:: 2T2BAMCA3PC010356

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Overview

Reviews

FAQs

CarGurus Analysis: 2022 Lexus RX

Summary

With 2,526 currently listed for sale on CarGurus and an average price of $40,414.60, 35.6% of 2022 Lexus RXs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus RX 4.6 / 5 stars and CarGurus experts gave it an 7.3 / 10.
84.2% of 2022 RX models on CarGurus are accident free.
The 2022 Lexus RX combined a smooth ride quality with standard advanced safety features, solidifying its status as the brand's best-selling model despite its aging design.

Why it stands out

The 2022 Lexus RX stood out for its exceptional ride quality, ensuring a comfortable driving experience that many owners appreciated. It also included standard advanced safety features, reflecting Lexus's commitment to driver and passenger safety. Despite its dated design and some ergonomic considerations, the RX maintained strong sales figures, showcasing its enduring appeal in the luxury SUV market.

Other model years to consider

2020 Lexus RX: This year offers $33,379.27 average price, 33% good/great deals, 4.8/5 user rating, 8.2/10 expert rating, 1,269 listings.
2021 Lexus RX: This year offers $35,773.39 average price, 32% good/great deals, 4.7/5 user rating, 7.8/10 expert rating, 1,829 listings.
2023 Lexus RX: This year offers $47,405.06 average price, 37% good/great deals, 4.6/5 user rating, 7.2/10 expert rating, 3,056 listings.

This analysis is based on CarGurus' proprietary market data from December 16, 2025, CarGurus experts' opinions, and generative AI.

4.6 Overall rating

(24 reviews)

Anonymous

5.0

Reviewed a 2022 Lexus RX on Feb 19, 2024

I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!

Uday T

4.0

Reviewed a 2022 Lexus RX on Jun 06, 2023

Great car, drives smooth. Lacks pick up power for a V6

Anonymous

5.0

Reviewed a 2022 Lexus 350 AWD on Jun 06, 2023

No unneeded frills but lots of quality of life items. Love the backup camera and surround view, easily the best one out of all the cars we test drove (GMC, Buick, Ford, Nissan). Suspension is solid, corners well, and plenty of power.

Anonymous

4.0

Reviewed a 2022 Lexus 350 FWD on Feb 08, 2023

Car is wonderful except for the gas mileage. Pretty, nice size, comfortable, good safety features.

Anonymous

5.0

Reviewed a 2022 Lexus 350 FWD on Oct 03, 2022

An excellent car which is loaded with features and fun to drive. It is smooth and has a very quiet cabin. Also very luxurious materials in the cabin and fine leather seats,

2022 Lexus RX FAQs

How much does the 2022 Lexus RX cost in South Carolina?

The average 2022 Lexus RX costs about $39,856.70. The average price has decreased by -4.9% since last year. The 164 for sale near South Carolina on CarGurus, range from $26,708 to $55,460 in price.

Is the 2022 Lexus RX a good car?

CarGurus experts gave the 2022 Lexus RX an overall rating of 7.3/10 and 2022 Lexus RX owners have rated the vehicle a 4.6/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Lexus RX vehicles in South Carolina have no reported accidents or damage?

159 out of 164 for sale near South Carolina have no reported accidents or damage.

Is the 2022 Lexus RX safe?

CarGurus experts gave the 2022 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2022 Lexus RX?

Depending on the engine and options, the 2022 Lexus RX gets between 21 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

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