Used 2021 Mercedes-Benz E-Class for Sale near Temecula, CA
186 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 839 currently listed for sale and an average price of $38,576.00, 34.7% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
75.6% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features a luxurious interior with advanced technology and multiple powertrain options, catering to a diverse range of buyer preferences.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall

Summary
With 839 currently listed for sale and an average price of $38,576.00, 34.7% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
75.6% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features a luxurious interior with advanced technology and multiple powertrain options, catering to a diverse range of buyer preferences.
Why it stands out
The 2021 Mercedes-Benz E-Class offers a compelling combination of luxury, performance, and cutting-edge technology, making it one of the most desirable midsize sedans on the market. With multiple body styles—sedan, coupe, convertible, and wagon—and a choice of powerful inline-six engines, including hybrid options, it provides flexibility for various driving preferences. The interior is richly appointed, with high-quality materials and advanced tech features like the revamped infotainment system, making it a truly inviting space. The expert test drive highlights that for 2021, the E-Class receives notable updates, including a mid-cycle refresh of its infotainment and styling, ensuring it remains competitive in the luxury segment. Despite some critiques regarding its pricing and the lack of certain standard advanced safety features, the E-Class continues to impress with its ride quality and performance, appealing to buyers who prioritize luxury and comfort.
Other model years to consider
- Average price: $41,002.00
- Good/great deal percentage: 33.2%
- User rating: 5 / 5
- Total listings: 1,064
- Average price: $30,559.00
- Good/great deal percentage: 33.4%
- User rating: 5 / 5
- Total listings: 979
- Average price: $23,891.00
- Good/great deal percentage: 34.0%
- User rating: 4.76 / 5
- Total listings: 1,395
This analysis is based on CarGurus' proprietary market data from May 25, 2026, CarGurus experts' opinions, and generative AI.
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2026 Mercedes-Benz E-Class Pricing, Specs, and Release Date
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2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
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4.7 Overall rating
Filter by rating
ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Teddi R
Reviewed a 2021 Mercedes-Benz E-Class on Jun 2, 2024
You cant go wrong with any of the E-class Mercedes! They are bulletproof cars with NO issues.
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
Elvis K. N
Reviewed a 2021 Mercedes-Benz E-Class on Jan 29, 2023
Very nice car but does not have active lane keeping assist.
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| AMG E 63 S Wagon 4MATIC | $112,450 |
| E 450 Cabriolet RWD | $71,950 |
| E 450 4MATIC Coupe AWD | $67,450 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| E 350 4MATIC | $56,750 |
| E 350 RWD | $54,250 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
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