Used 2021 Mercedes-Benz E-Class for Sale near Temecula, CA
184 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 906 currently listed for sale and an average price of $38,534.00, 29.7% of 2021 Mercedes-Benz E-Class vehicles for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.53 / 5 stars.
76.2% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features a stunning design, robust performance options, and advanced technology, making it a choice luxury car.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall

Summary
With 906 currently listed for sale and an average price of $38,534.00, 29.7% of 2021 Mercedes-Benz E-Class vehicles for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.53 / 5 stars.
76.2% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class features a stunning design, robust performance options, and advanced technology, making it a choice luxury car.
Why it stands out
The 2021 Mercedes-Benz E-Class is distinguished by its exceptional blend of luxury, performance, and cutting-edge technology. It offers a diverse range of powertrains, including new hybrid options, and showcases an elegant exterior design with an updated infotainment system. The inclusion of features such as advanced safety technologies and high-quality interior materials provides both comfort and security, making it appealing to buyers seeking sophistication in a midsize luxury sedan. Though some advanced features may not be standard, the overall ride quality and technology enhancements offer a compelling value for its class. Moreover, CarGurus experts rated the vehicle a strong 8.33 out of 10, highlighting its performance and interior excellence.
Other model years to consider
- Average price: $41,269.00
- Good/great deal percentage: 30.5%
- User rating: 5 / 5
- Total listings: 1,125
- Average price: $14,904.00
- Good/great deal percentage: 37.1%
- User rating: 4.64 / 5
- Total listings: 1,365
- Average price: $27,843.00
- Good/great deal percentage: 32.0%
- User rating: 4.88 / 5
- Total listings: 1,173
This analysis is based on CarGurus' proprietary market data from April 6, 2026, CarGurus experts' opinions, and generative AI.
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2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
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4.7 Overall rating
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ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Teddi R
Reviewed a 2021 Mercedes-Benz E-Class on Jun 2, 2024
You cant go wrong with any of the E-class Mercedes! They are bulletproof cars with NO issues.
Anonymous
Reviewed a 2021 Mercedes-Benz E-Class on May 2, 2024
Ive owned many Mercedes over the years but always come back to Model E. Best size, forward technology and usually handsome exterior/interior
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| E 450 4MATIC Cabriolet AWD | $74,450 |
| AMG E 63 S Wagon 4MATIC | $112,450 |
| E 450 4MATIC Coupe AWD | $67,450 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| E 350 4MATIC | $56,750 |
| E 350 RWD | $54,250 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
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