Used 2022 Mercedes-Benz E-Class for Sale near Temecula, CA
172 results
CarGurus Analysis:
2022 Mercedes-Benz E-Class
With 1,090 currently listed for sale and an average price of $41,721.00, 30.6% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars.
85.8% of 2022 E-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz E-Class lineup continues to impress with various body styles and a luxurious interior featuring advanced technology like the MBUX infotainment system.
CarGurus Analysis: 2022 Mercedes-Benz E-Class
overall

Summary
With 1,090 currently listed for sale and an average price of $41,721.00, 30.6% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars.
85.8% of 2022 E-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz E-Class lineup continues to impress with various body styles and a luxurious interior featuring advanced technology like the MBUX infotainment system.
Why it stands out
The 2022 Mercedes-Benz E-Class stands out in a competitive market for its blend of luxury, technology, and performance. Its availability in multiple body styles—including coupe, convertible, sedan, and station wagon—ensures that there's an E-Class for nearly every taste. The expert review highlights that, following a refresh for the 2021 model, the 2022 series maintains high standards in both performance and comfort, with the E450 and AMG E53 variants offering powerful engine options, enhanced with the EQ Boost technology. Owners also benefit from a sophisticated cabin finished with premium materials, confident handling, and a comprehensive suite of safety features. While it leans towards the higher end of the pricing spectrum, those looking for an emblem of luxury will find the E-Class's appeal hard to overlook.
Other model years to consider
- Average price: $18,834.00
- Good/great deal percentage: 33.5%
- User rating: 4.78 / 5
- Total listings: 1,335
- Average price: $23,747.00
- Good/great deal percentage: 32.2%
- User rating: 4.76 / 5
- Total listings: 1,379
- Average price: $30,791.00
- Good/great deal percentage: 29.3%
- User rating: 5 / 5
- Total listings: 964
This analysis is based on CarGurus' proprietary market data from April 13, 2026, CarGurus experts' opinions, and generative AI.
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2026 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Sitting squarely in the midsize luxury sedan segment, the 2026 Mercedes-Benz E-Class competes with the BMW 5 Series, the Audi A6, and the Lexus ES.

2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Thoroughly updated last year, the Mercedes-Benz E-Class returns for 2025 with added safety equipment, a new entry-level trim, and an AMG E 53 Hybrid version designed to deliver equal parts performance and efficiency.
5.0 Overall rating
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Jim S
Reviewed a 2022 Mercedes-Benz E-Class on Mar 6, 2025
The E-class is the midsize line of Mercedes cars, so it’s fine for all sizes except for very tall and large people. The new inline six cylinder is my favorite engine because it has plenty of power and is fuel efficient. Overall, the quality is here and has been for years.
Anonymous
Reviewed a 2022 Mercedes-Benz E-Class on Jul 12, 2024
Great value. 39K with 14K miles and in great condition with premium package. Took it to the Mercedes dealer for inspection and they said it was in great shape (tires, brakes, belts, filters, oil, fluid level, electronics, and even spark plugs). The interior was in pristine condition and the exterior is just as perfect.
Jim S
Reviewed a 2022 Mercedes-Benz E-Class on Mar 7, 2025
The E-class Mercedes Is the midsize car segment, and is large enough for many people who are not over 6’ 6” or more than 380 pounds in my estimation. Quality is noticed in interior seating and fit and finish. The relatively new Inline six cylinder engine has enough power with above average fuel economy. Other engines are available in four cylinder and eight cylinder variants.
Bill F
Reviewed a 2022 Mercedes-Benz E-Class on Jan 7, 2023
First class, quality material and build! You know maintenance is expensive going into it, but it is what it is.
2022 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| E 450 Cabriolet RWD | $73,250 |
| E 450 4MATIC Coupe AWD | $68,600 |
| AMG E 53 Coupe 4MATIC | $77,600 |
| E 450 Coupe RWD | $66,100 |
| AMG E 53 Sedan 4MATIC | $75,000 |
| E 450 4MATIC Sedan AWD | $62,750 |
| E 350 4MATIC | $57,450 |
| E 350 RWD | $54,950 |
2022 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz E-Class prices has changed over time.
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