Used 2022 Mercedes-Benz E-Class for Sale nearIrvine, CA
174 vehicles found
See the total price upfront.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 4,680
- Stock #:
- X17726
- VIN:
- W1KZF6BB8NB054025
Sponsored by STG Auto Group of Bellflower
2022 Mercedes-Benz E-Class
AMG E 53 Sedan 4MATIC
4,680 mi
$57,623
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 2 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 18,669
- Stock #:
- P56261
- VIN:
- W1K1J5KB5PF198021
Sponsored Listing
2023 Mercedes-Benz E-Class
E 450 4MATIC
18,669 mi
$49,977
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Convertible
- Doors:
- 2 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 17,692
- Stock #:
- RC4004
- VIN:
- W1K1K5JBXPF201901
Sponsored Listing
2023 Mercedes-Benz E-Class
E 450 RWD
17,692 mi
$53,810
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 40,687
- Stock #:
- 61838
- VIN:
- W1KZF8DB7NB087008
-$2,000
2022 Mercedes-Benz E-Class
E 350 RWD
40,687 mi
$33,080
$31,080
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Coupe
- Doors:
- 2 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Silver
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 46,120
- Stock #:
- 14033200
- VIN:
- W1K1J5JB0MF140332
2021 Mercedes-Benz E-Class
E 450 Coupe RWD
46,120 mi
$34,975
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 29,155
- Stock #:
- 260657A
- VIN:
- W1KZF8DB2MA914224
2021 Mercedes-Benz E-Class
E 350 RWD
29,155 mi
$35,585
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Obsidian Black Metallic
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 52,463
- Stock #:
- 031015
- VIN:
- W1KZF8DBXNB031015
2022 Mercedes-Benz E-Class
E 350 RWD
52,463 mi
$29,555
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Lunar Blue
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Nut Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 39,820
- Stock #:
- PFF00463
- VIN:
- W1KZF5KB0MA939818
2021 Mercedes-Benz E-Class
E 450 4MATIC Sedan AWD
39,820 mi
$38,961
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Convertible
- Doors:
- 2 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 33,383
- Stock #:
- N189956A
- VIN:
- W1K1J5JB2PF202835
-$1,001
2023 Mercedes-Benz E-Class
E 450 RWD
33,383 mi
$45,977
$44,976
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 67,716
- Stock #:
- 9238
- VIN:
- W1KZF6BB3NB013379
2022 Mercedes-Benz E-Class
AMG E 53 Sedan 4MATIC
67,716 mi
$43,478
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Coupe
- Doors:
- 2 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 13,249
- Stock #:
- 28490787
- VIN:
- W1K1J5JB1NF186012
2022 Mercedes-Benz E-Class
E 450 Coupe RWD
13,249 mi
$47,997
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Gray Metallic
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black Nappa
- Transmission:
- 9-Speed Automatic
- Mileage:
- 44,513
- Stock #:
- B098893L
- VIN:
- W1KZF8DB1NB098893
2022 Mercedes-Benz E-Class
E 350 RWD
44,513 mi
$34,372
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (TAN)
- Transmission:
- Automatic
- Mileage:
- 14,043
- Stock #:
- 28465263
- VIN:
- W1KZF8EBXPB150085
2023 Mercedes-Benz E-Class
E 350 4MATIC
14,043 mi
$41,997
CarGurus Analysis:
2022 Mercedes-Benz E-Class
With 1,071 currently listed for sale and an average price of $40,899.00, 33.3% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars.
85.3% of 2022 E-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz E-Class features a variety of body styles, including coupe, convertible, sedan, and station wagon, and offers advanced technology with the MBUX infotainment system.
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Coupe
- Doors:
- 2 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 30,587
- Stock #:
- 28974092
- VIN:
- W1K1J5JB7NF186824
2022 Mercedes-Benz E-Class
E 450 Coupe RWD
30,587 mi
$45,997
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 2 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 18,669
- Stock #:
- P56261
- VIN:
- W1K1J5KB5PF198021
2023 Mercedes-Benz E-Class
E 450 4MATIC
18,669 mi
$49,977
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Coupe
- Doors:
- 2 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Mojave Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black/Red
- Transmission:
- 9-Speed Automatic
- Mileage:
- 23,010
- Stock #:
- V4600
- VIN:
- W1K1J6BB4MF161298
2021 Mercedes-Benz E-Class
AMG E 53 Coupe 4MATIC
23,010 mi
$50,000
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Coupe
- Doors:
- 2 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 23,706
- Stock #:
- P168247
- VIN:
- W1K1J5KB8MF168247
2021 Mercedes-Benz E-Class
E 450 4MATIC Coupe AWD
23,706 mi
$43,093
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Magma Grey)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 29,714
- Stock #:
- R977242
- VIN:
- W1KZF8EB2MA977242
2021 Mercedes-Benz E-Class
E 350 4MATIC
29,714 mi
$31,229
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 25,762
- Stock #:
- NB080698
- VIN:
- W1KZF8DB1NB080698
2022 Mercedes-Benz E-Class
E 350 RWD
25,762 mi
$34,841
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Brilliant Blue Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 48,013
- Stock #:
- 252553
- VIN:
- W1KZF8DB4MA999731
2021 Mercedes-Benz E-Class
E 350 RWD
48,013 mi
$29,429
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Polar White
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black Mb)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 27,500
- Stock #:
- 095035
- VIN:
- W1KZF8DB6NB095035
2022 Mercedes-Benz E-Class
E 350 RWD
27,500 mi
$34,980
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 39,535
- Stock #:
- 43801UC
- VIN:
- W1KZF8DB1MB000346
2021 Mercedes-Benz E-Class
E 350 RWD
39,535 mi
$32,845
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 38,162
- Stock #:
- LR56290
- VIN:
- W1KZF8DB4PB186923
-$1,001
Sponsored Listing
2023 Mercedes-Benz E-Class
E 350 RWD
38,162 mi
$38,978
$37,977
CarGurus Analysis: 2022 Mercedes-Benz E-Class
overall
Summary
With 1,071 currently listed for sale and an average price of $40,899.00, 33.3% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars.
85.3% of 2022 E-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz E-Class features a variety of body styles, including coupe, convertible, sedan, and station wagon, and offers advanced technology with the MBUX infotainment system.
Why it stands out
The 2022 Mercedes-Benz E-Class stands out in the luxury vehicle segment due to its impressive versatility and high-quality craftsmanship. Available in multiple body styles, including coupe, convertible, sedan, and station wagon, it caters to a wide range of preferences and needs. The E-Class is equipped with advanced technology, highlighted by the MBUX infotainment system, which features two high-resolution 12.3-inch screens and offers seamless smartphone integration. The vehicle's performance is equally commendable, with options for turbocharged four-cylinder and six-cylinder engines, ensuring a balance of power and efficiency. Additionally, the E-Class is designed with luxury in mind, featuring high-end materials and comfort-focused amenities, such as heated seats and a sophisticated sound system. While it may not be the most cost-effective option in its class, the E-Class delivers a driving experience that is both engaging and refined, making it a compelling choice for luxury car buyers.
Other model years to consider
- Average price: $23,544.00
- Good/great deal percentage: 35.3%
- User rating: 4.76 / 5
- Total listings: 1,395
- Average price: $31,571.00
- Good/great deal percentage: 34.7%
- User rating: 5 / 5
- Total listings: 998
- Average price: $18,694.00
- Good/great deal percentage: 34.8%
- User rating: 4.78 / 5
- Total listings: 1,334
This analysis is based on CarGurus' proprietary market data from July 6, 2026, CarGurus experts' opinions, and generative AI.
5.0 Overall rating
Filter by rating
Jim S
Reviewed a 2022 Mercedes-Benz E-Class on Mar 6, 2025
The E-class is the midsize line of Mercedes cars, so it’s fine for all sizes except for very tall and large people. The new inline six cylinder is my favorite engine because it has plenty of power and is fuel efficient. Overall, the quality is here and has been for years.
Anonymous
Reviewed a 2022 Mercedes-Benz E-Class on Jul 12, 2024
Great value. 39K with 14K miles and in great condition with premium package. Took it to the Mercedes dealer for inspection and they said it was in great shape (tires, brakes, belts, filters, oil, fluid level, electronics, and even spark plugs). The interior was in pristine condition and the exterior is just as perfect.
Jim S
Reviewed a 2022 Mercedes-Benz E-Class on Mar 7, 2025
The E-class Mercedes Is the midsize car segment, and is large enough for many people who are not over 6’ 6” or more than 380 pounds in my estimation. Quality is noticed in interior seating and fit and finish. The relatively new Inline six cylinder engine has enough power with above average fuel economy. Other engines are available in four cylinder and eight cylinder variants.
Bill F
Reviewed a 2022 Mercedes-Benz E-Class on Jan 7, 2023
First class, quality material and build! You know maintenance is expensive going into it, but it is what it is.
2022 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| E 450 4MATIC Coupe AWD | $68,600 |
| E 450 Cabriolet RWD | $73,250 |
| AMG E 53 Coupe 4MATIC | $77,600 |
| E 450 4MATIC Sedan AWD | $62,750 |
| E 450 Coupe RWD | $66,100 |
| AMG E 53 Sedan 4MATIC | $75,000 |
| E 350 4MATIC | $57,450 |
| E 350 RWD | $54,950 |
2022 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz E-Class prices has changed over time.
See more price trendsFAQs
How much does the 2022 Mercedes-Benz E-Class cost in Irvine, CA?
Is the 2022 Mercedes-Benz E-Class a good car?
How many 2022 Mercedes-Benz E-Class vehicles in Irvine, CA have no reported accidents or damage?
Is the 2022 Mercedes-Benz E-Class safe?
What is the fuel economy of the 2022 Mercedes-Benz E-Class?
What fuel types are available?
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