Used 2021 Lexus ES for Sale near Saint Louis, MO
62 results
- Year:
- 2021
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 64,267
- Stock #:
- PJD04486
- VIN:
- 58ACZ1B17MU084285


Sponsored by Napleton Saint Louis Nissan
2021 Lexus ES
350 FWD
64,267 mi
$29,345
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Palomino
- Transmission:
- 8-Speed Automatic
- Mileage:
- 23,430
- Stock #:
- B87511
- VIN:
- 58ADZ1B1XNU132285

Sponsored Listing
2022 Lexus ES
350 FWD
23,430 mi
$38,394
- Year:
- 2021
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 100,464
- Stock #:
- P4U107474
- VIN:
- 58ACZ1B16MU107474

Sponsored Listing
2021 Lexus ES
350 FWD
100,464 mi
$26,969
- Year:
- 2021
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 64,267
- Stock #:
- PJD04486
- VIN:
- 58ACZ1B17MU084285

2021 Lexus ES
350 FWD
64,267 mi
$29,345
- Year:
- 2020
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- Automatic
- Mileage:
- 44,788
- Stock #:
- 082065A
- VIN:
- 58ADZ1B11LU082065

2020 Lexus ES
350 FWD
44,788 mi
$29,032
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 33,872
- Stock #:
- 1411C
- VIN:
- 58ADZ1B11NU129680

2022 Lexus ES
350 FWD
33,872 mi
$36,966
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Palomino
- Transmission:
- 8-Speed Automatic
- Mileage:
- 23,430
- Stock #:
- B87511
- VIN:
- 58ADZ1B1XNU132285

2022 Lexus ES
350 FWD
23,430 mi
$38,394
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 31,445
- Stock #:
- 23886FRC
- VIN:
- 58ADZ1B1XNU123702

2022 Lexus ES
350 FWD
31,445 mi
$37,202
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Brown (Tan)
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 23,600
- Stock #:
- 70047330
- VIN:
- 58ACZ1B18NU135679

2022 Lexus ES
350 FWD
23,600 mi
$37,197
- Year:
- 2021
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 68,619
- Stock #:
- 70051046
- VIN:
- 58ADZ1B13MU086474

2021 Lexus ES
350 FWD
68,619 mi
$31,397
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rich Creme
- Transmission:
- 8-Speed Automatic
- Mileage:
- 41,968
- Stock #:
- NU135876
- VIN:
- 58ADZ1B14NU135876

2022 Lexus ES
350 FWD
41,968 mi
$35,044
- Year:
- 2020
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Brown (Moonbeam Beige Metallic)
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Chateau
- Transmission:
- 8-Speed Automatic
- Mileage:
- 97,508
- Stock #:
- APLU054797
- VIN:
- 58ADZ1B11LU054797

2020 Lexus ES
350 FWD
97,508 mi
$24,496
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 203 hp 2.5L I4
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Gasoline
- Interior color:
- Palomino
- Transmission:
- 8-Speed Automatic
- Mileage:
- 32,230
- Stock #:
- 009864
- VIN:
- 58AC11D13NU009864

2022 Lexus ES
250 AWD
32,230 mi
$33,486
CarGurus Analysis:
2021 Lexus ES
With 67 currently listed for sale near Saint Louis, MO and an average price of $29,592.00, 49.3% of 2021 Lexus ES models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus ES 4.86 / 5 stars.
94.0% of 2021 Lexus ES models on CarGurus are accident-free.
The 2021 Lexus ES features a roomy and quiet cabin, a variety of powertrain options including a new ES 250 series, and a solid reputation for comfort and reliability.
- Year:
- 2020
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 76,700
- Stock #:
- 078123
- VIN:
- 58ADZ1B12LU078123

2020 Lexus ES
350 FWD
76,700 mi
$28,079
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- NIGHTFALL MICA (DARK BLUE)
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- PALOMINO (SADDLE)
- Transmission:
- Automatic
- Mileage:
- 31,939
- Stock #:
- GJ9009A
- VIN:
- 58ADZ1B19NU130026

2022 Lexus ES
350 FWD
31,939 mi
$38,346
- Year:
- 2021
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Red
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (TAN)
- Transmission:
- Automatic
- Mileage:
- 17,555
- Stock #:
- 70056845
- VIN:
- 58AFZ1B11MU109436

2021 Lexus ES
350 Ultra Luxury FWD
17,555 mi
$45,397
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 25,806
- Stock #:
- 28508051
- VIN:
- 58AJZ1B15NU139115

2022 Lexus ES
350 F Sport FWD
25,806 mi
$42,247
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Palomino
- Transmission:
- 8-Speed Automatic
- Mileage:
- 13,774
- Stock #:
- 116994
- VIN:
- 58ADZ1B13NU116994

2022 Lexus ES
350 FWD
13,774 mi
$39,317
- Year:
- 2020
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Blue
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (TAN)
- Transmission:
- Automatic
- Mileage:
- 68,551
- Stock #:
- M1795
- VIN:
- 58ADZ1B15LU080853

2020 Lexus ES
350 FWD
68,551 mi
$28,951
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black W/Hadori Aluminum
- Transmission:
- 8-Speed Automatic
- Mileage:
- 59,278
- Stock #:
- R5444XR
- VIN:
- 58AGZ1B14NU125099

2022 Lexus ES
350 F Sport FWD
59,278 mi
$38,678
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Acorn
- Transmission:
- Automatic
- Mileage:
- 26,209
- Stock #:
- NU129820
- VIN:
- 58ADZ1B12NU129820

2022 Lexus ES
350 FWD
26,209 mi
$38,679
- Year:
- 2021
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 100,464
- Stock #:
- P4U107474
- VIN:
- 58ACZ1B16MU107474

2021 Lexus ES
350 FWD
100,464 mi
$26,969
- Year:
- 2022
- Make:
- Lexus
- Model:
- ES
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 302 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 33,872
- Stock #:
- 1411C
- VIN:
- 58ADZ1B11NU129680

Sponsored Listing
2022 Lexus ES
350 FWD
33,872 mi
$36,966
CarGurus Analysis: 2021 Lexus ES
overall

Summary
With 67 currently listed for sale near Saint Louis, MO and an average price of $29,592.00, 49.3% of 2021 Lexus ES models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus ES 4.86 / 5 stars.
94.0% of 2021 Lexus ES models on CarGurus are accident-free.
The 2021 Lexus ES features a roomy and quiet cabin, a variety of powertrain options including a new ES 250 series, and a solid reputation for comfort and reliability.
Why it stands out
The 2021 Lexus ES distinguishes itself with a blend of luxury and reliability that appeals to many buyers. An array of powertrain options, including a new 2.5-liter four-cylinder engine in the ES 250 series, expands its appeal while maintaining the same pricing as its V6 counterpart, the ES 350. The ES is celebrated for its spacious and tranquil cabin, where attention to comfort and detail is evident in the quality materials used throughout. Additionally, this model is equipped with advanced technology features, including the Lexus Safety System 2.0, enhancing its safety profile. Though some may find its performance more pedestrian than sporty, enthusiasts looking for comfort without sacrificing style or reliability should find the 2021 ES particularly appealing.
Other model years to consider
- Average price: $31,618.00
- Good/great deal percentage: 63.8%
- User rating: 5 / 5
- Total listings: 58
- Average price: $16,749.00
- Good/great deal percentage: 37.5%
- User rating: 4.78 / 5
- Total listings: 56
- Average price: $20,637.00
- Good/great deal percentage: 54.8%
- User rating: 4.5 / 5
- Total listings: 62
This analysis is based on CarGurus' proprietary market data from June 16, 2026, CarGurus experts' opinions, and generative AI.
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4.9 Overall rating
Filter by rating
Nuno M
Reviewed a 2021 Lexus 350 F Sport FWD on Nov 16, 2025
Love the look and styling the ride is smooth and the interior is amazing
Amy H
Reviewed a 2021 Lexus 350 FWD on Feb 1, 2024
Excellent car. Very smooth and loaded with nice features.
Anonymous
Reviewed a 2021 Lexus ES on May 20, 2023
Smooth ride and the premium package is so nice with all you need. I absolutely love the car it is luxurious.
jon c
Reviewed a 2021 Lexus 350 F Sport FWD on Jun 26, 2023
looks good, drives good, super comfortable, decent tech, efficient and it drinks regular fuel...car is even better than I expected
2021 Lexus ES Trims
| Trim type | MSRP |
|---|---|
| 250 Luxury AWD | $45,200 |
| 250 F Sport AWD | $45,800 |
| 350 Luxury FWD | $45,200 |
| 350 Ultra Luxury FWD | $49,000 |
| 350 F Sport FWD | $45,800 |
| 250 AWD | $40,000 |
| 350 FWD | $40,000 |
2021 Lexus ES Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus ES prices has changed over time.
See more price trends