Used 2021 Lexus ES for Sale near Saint Louis, MO
53 results
CarGurus Analysis:
2021 Lexus ES
With 52 currently listed for sale near Saint Louis, MO and an average price of $28,092.00, 78.8% of 2021 Lexus ES models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus ES 4.86 / 5 stars.
132.7% of 2021 ES models on CarGurus are accident free.
The 2021 Lexus ES introduced the new ES 250 series, offering standard all-wheel drive (AWD) and expanded safety features.
CarGurus Analysis: 2021 Lexus ES
overall

Summary
With 52 currently listed for sale near Saint Louis, MO and an average price of $28,092.00, 78.8% of 2021 Lexus ES models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus ES 4.86 / 5 stars.
132.7% of 2021 ES models on CarGurus are accident free.
The 2021 Lexus ES introduced the new ES 250 series, offering standard all-wheel drive (AWD) and expanded safety features.
Why it stands out
The 2021 Lexus ES distinguishes itself in the luxury sedan market with its perfect blend of comfort, performance, and innovative features. Recognized for a plush ride and a choice of powertrains, including the new ES 250 with a 2.5-liter engine and AWD, it continues Lexus's tradition of excellence in design and reliability. The cabin is spacious and quiet, catering well to both drivers and passengers, making it a preferred choice for those prioritizing comfort. Although its handling may not match that of traditional sports sedans, the 2021 ES provides a remarkably smooth driving experience that resonates well with family-oriented buyers. Additionally, new safety technologies, such as Lexus Safety System 2.0, enhance its appeal, ensuring peace of mind on the road.
Other model years to consider
- Average price: $27,432.00
- Good/great deal percentage: 74.2%
- User rating: 5 / 5
- Total listings: 62
- Average price: $14,417.00
- Good/great deal percentage: 25.0%
- User rating: 4.78 / 5
- Total listings: 44
- Average price: $34,982.00
- Good/great deal percentage: 90.4%
- User rating: 5 / 5
- Total listings: 52
This analysis is based on CarGurus' proprietary market data from April 14, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles

The Best Sedans of 2026
As more people flock to SUVs and crossovers, some automakers are killing off sedans. But others are doubling down, building some of the best four-door cars we’ve ever driven. For a supposedly dying segment, the sedan market looks awfully healthy.

The Best Affordable Luxury Cars in 2026
There are plenty of great options for affordable new luxury cars, if you know where to look. Our expert guide gives you the lowdown on the best cheap luxury cars you can buy.

The Most Reliable Luxury Cars of 2026
Luxury cars give you the best of most things but which are the most reliable luxury cars you can buy? Our guide has all the details.
4.9 Overall rating
Filter by rating
Nuno M
Reviewed a 2021 Lexus 350 F Sport FWD on Nov 16, 2025
Love the look and styling the ride is smooth and the interior is amazing
Amy H
Reviewed a 2021 Lexus 350 FWD on Feb 1, 2024
Excellent car. Very smooth and loaded with nice features.
Anonymous
Reviewed a 2021 Lexus ES on May 20, 2023
Smooth ride and the premium package is so nice with all you need. I absolutely love the car it is luxurious.
jon c
Reviewed a 2021 Lexus 350 F Sport FWD on Jun 26, 2023
looks good, drives good, super comfortable, decent tech, efficient and it drinks regular fuel...car is even better than I expected
2021 Lexus ES Trims
| Trim type | MSRP |
|---|---|
| 250 Luxury AWD | $45,200 |
| 250 F Sport AWD | $45,800 |
| 350 Luxury FWD | $45,200 |
| 350 Ultra Luxury FWD | $49,000 |
| 350 F Sport FWD | $45,800 |
| 250 AWD | $40,000 |
| 350 FWD | $40,000 |
2021 Lexus ES Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus ES prices has changed over time.
See more price trends







