2021 Chrysler 300 vs 2021 Mercedes-Benz S-Class

You might think the 2021 Chrysler 300 is getting long in the tooth. And you’d be right. This car is so old that it's been through three different car companies (if you count the first generation). But like an aging starting catcher who has watched three different managers come and go, the Chrysler 300 still delivers on a daily basis.

It provides North American consumers with a proper front-engine, rear-wheel drive (RWD) luxury sedan at a reasonable price. No other American manufacturer offers that, and you’d be hard-pressed to find anything that competes with it from Europe, Japan or Korea.

Starting at just $31,000 MSRP, and offering options for all-wheel drive (AWD) or a 5.7-liter Hemi V8 engine, it’s no wonder that an average of 43,000 new car buyers a year have found the 300 so appealing since the second generation arrived for the 2011 model year.

The S-Class not only sits at the top of the Mercedes hierarchy in price and prestige, but it has also long served as a technological showcase. In the press release for the redesigned 2021 S-Class, Mercedes repeatedly noted the innovations—from anti-lock brakes to airbags—that were introduced on the big sedan and eventually trickled down to mainstream vehicles.

With the previous generation dating back to the 2014 model year (with a significant update for 2018), the Mercedes-Benz S-Class was in need of an update to maintain that status, and to keep pace with other full-size luxury sedans like the Audi A8, BMW 7 Series, and Lexus LS. To do that, the new S-Class gets a more sophisticated infotainment system, new powertrains, and more aerodynamic bodywork, among other features.

The 2021 S-Class launches in two configurations, both with 4Matic all-wheel drive (AWD) and EQ Boost mild-hybrid systems. The S500 4Matic has a six-cylinder engine, while the S580 4Matic has a V8. We spent a few days with the Mercedes-Benz S580 for this review. A Mercedes-Maybach S680 4Matic version will follow in the first half of 2022, and you can expect a new AMG performance version sometime in the future as well.