Used 2022 Lexus RX for Sale nearSan Francisco, CA
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 80,498
- Stock #:
- NC325831I
- VIN:
- 2T2YZMDA6NC325831


Sponsored by Capitol Nissan
2022 Lexus RX
350 F Sport Handling AWD
80,498 mi
$34,922
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Mica
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 20,490
- Stock #:
- TPC018884
- VIN:
- 2T2BAMBA0PC018884

-$1,000
Sponsored Listing
2023 Lexus RX
350 FWD
20,490 mi
$44,075
$43,075
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 25,280
- Stock #:
- CH1537
- VIN:
- JTJCHMAA3P2008822

-$2,086
Sponsored Listing
2023 Lexus RX
350 Premium FWD
25,280 mi
$49,580
$47,494
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Grecian Water
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 42,489
- Stock #:
- TZ310175A
- VIN:
- 2T2YZMDA6NC354830

2022 Lexus RX
350 F Sport Handling AWD
42,489 mi
$40,201
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 58,496
- Stock #:
- AP10543
- VIN:
- 2T2AZMAA9NC247549

-$1,197
2022 Lexus RX
350 FWD
58,496 mi
$35,082
$33,885
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Nori Green Pearl
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 24,577
- Stock #:
- 61F06520
- VIN:
- 2T2BAMCA2PC036429

2023 Lexus RX
350 Premium AWD
24,577 mi
$48,270
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Palomino
- Transmission:
- 8-Speed Automatic
- Mileage:
- 29,493
- Stock #:
- 23083N
- VIN:
- 2T2BAMCA8PC001653

2023 Lexus RX
350 Premium AWD
29,493 mi
$44,588
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 26,370
- Stock #:
- 3P07790
- VIN:
- 2T2BAMBAXPC007830

2023 Lexus RX
350 Premium FWD
26,370 mi
$45,073
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 76,944
- Stock #:
- DNC234693
- VIN:
- 2T2HZMAA8NC234693

2022 Lexus RX
350 FWD
76,944 mi
$38,172
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver Metallic
- Fuel type:
- Gasoline
- Interior color:
- Black (Ebony)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 23,111
- Stock #:
- 256646
- VIN:
- 2T2HZMAAXNC256646

2022 Lexus RX
350 Luxury AWD
23,111 mi
$43,995
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 52,930
- Stock #:
- P15356
- VIN:
- JTJHZKEA6N2023667

2022 Lexus RX
350L FWD
52,930 mi
$35,362
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Orange
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (BEIGE)
- Transmission:
- Automatic
- Mileage:
- 21,601
- Stock #:
- 19682
- VIN:
- 2T2BAMCA3PC005741

2023 Lexus RX
350 Luxury AWD
21,601 mi
$46,601
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 43,831
- Stock #:
- YN2041894
- VIN:
- JTJHZKFAXN2041894

2022 Lexus RX
350L AWD
43,831 mi
$39,584
CarGurus Analysis:
2022 Lexus RX
With 114 currently listed for sale near San Francisco, CA and an average price of $37,901.00, 80.7% of 2022 Lexus RX models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus RX 4.75 / 5 stars.
100.0% of 2022 RX models on CarGurus are accident free.
The 2022 Lexus RX is known for its luxurious interior, advanced safety features, and smooth driving experience, although some drivers noted a lack of pick-up power and average gas mileage.
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- Automatic
- Mileage:
- 50,428
- Stock #:
- SPC011745
- VIN:
- 2T2BAMCA8PC011745

2023 Lexus RX
350 Luxury AWD
50,428 mi
$41,081
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 25,511
- Stock #:
- 027741
- VIN:
- 2T2BAMCA3PC027741

2023 Lexus RX
350 F Sport Handling AWD
25,511 mi
$50,369
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Transmission:
- 8-Speed Automatic
- Mileage:
- 48,997
- Stock #:
- 207994
- VIN:
- 2T2HZMAAXMC207994

2021 Lexus RX
350 FWD
48,997 mi
$33,583
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 92,775
- Stock #:
- 54822A
- VIN:
- 2T2SZMDAXMC285273

2021 Lexus RX
350 F Sport AWD
92,775 mi
$31,883
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 118,291
- Stock #:
- 346956
- VIN:
- 2T2YZMDAXNC346956

-$690
2022 Lexus RX
350 F Sport Handling AWD
118,291 mi
$31,773
$31,083
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 46,455
- Stock #:
- B12361
- VIN:
- 2T2AZMAA6NC238937

2022 Lexus RX
350 FWD
46,455 mi
$34,546
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 29,279
- Stock #:
- SPC013343
- VIN:
- 2T2BAMBA7PC013343

2023 Lexus RX
350 Premium+ FWD
29,279 mi
$43,081
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 30,271
- Stock #:
- C033034A
- VIN:
- 2T2BAMCA8PC033034

2023 Lexus RX
350 Premium AWD
30,271 mi
$43,085
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Palomino
- Transmission:
- Automatic
- Mileage:
- 43,057
- Stock #:
- 23624
- VIN:
- 2T2BAMCA4PC026503

2023 Lexus RX
350 Premium AWD
43,057 mi
$44,073
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- Automatic
- Mileage:
- 50,428
- Stock #:
- SPC011745
- VIN:
- 2T2BAMCA8PC011745

Sponsored Listing
2023 Lexus RX
350 Luxury AWD
50,428 mi
$41,081
CarGurus Analysis: 2022 Lexus RX
overall
Summary
With 114 currently listed for sale near San Francisco, CA and an average price of $37,901.00, 80.7% of 2022 Lexus RX models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus RX 4.75 / 5 stars.
100.0% of 2022 RX models on CarGurus are accident free.
The 2022 Lexus RX is known for its luxurious interior, advanced safety features, and smooth driving experience, although some drivers noted a lack of pick-up power and average gas mileage.
Why it stands out
The 2022 Lexus RX continues to be a top choice in the midsize luxury crossover segment, thanks to its blend of comfort, style, and reliability. While it may not excel in performance, the RX is celebrated for its attractive design and high-quality interior, making it a favorite among buyers seeking a luxurious driving experience. The RX offers a variety of trims, including the sporty F Sport and the spacious L model, catering to different preferences. Notably, the RX is equipped with the Lexus Safety System 2.0+, which includes a suite of advanced driver assistance features, enhancing its appeal for safety-conscious consumers. Despite some criticisms regarding its infotainment system and engine responsiveness, the RX remains a strong contender for those prioritizing comfort and luxury over sporty performance.
Other model years to consider
- Average price: $45,747.00
- Good/great deal percentage: 77.7%
- User rating: 5 / 5
- Total listings: 139
- Average price: $37,120.00
- Good/great deal percentage: 86.8%
- User rating: 4.92 / 5
- Total listings: 68
- Average price: $34,322.00
- Good/great deal percentage: 62.9%
- User rating: 4.88 / 5
- Total listings: 70
This analysis is based on CarGurus' proprietary market data from August 4, 2026, CarGurus experts' opinions, and generative AI.
4.8 Overall rating
Filter by rating
Marc G
Reviewed a 2022 Lexus RX on Dec 29, 2025
Good and reliable vehicle. Luxury is the cornerstone of this SUV.
Terry C
Reviewed a 2022 Lexus RX on Apr 12, 2025
Non turbo Toyota reliability and smoothness and composure of a S class.
Uday T
Reviewed a 2022 Lexus RX on Jun 6, 2023
Great car, drives smooth. Lacks pick up power for a V6
Anonymous
Reviewed a 2022 Lexus RX on Feb 19, 2024
I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!
2022 Lexus RX Trims
| Trim type | MSRP |
|---|---|
| 350 Luxury AWD | -- |
| 350L Luxury FWD | $54,750 |
| 350 F Sport AWD | $50,800 |
| 350L FWD | $48,750 |
| 350L AWD | $50,150 |
| 350 F Sport Handling AWD | $53,200 |
| 350 AWD | $47,320 |
| 350 FWD | $45,920 |
2022 Lexus RX Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Lexus RX prices has changed over time.
See more price trendsFAQs
How much does the 2022 Lexus RX cost in San Francisco, CA?
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Is the 2022 Lexus RX safe?
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What fuel types are available?
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