Used 2021 Toyota Sienna for Sale near Santa Rosa, CA

## Summary - With 1,332 currently listed for sale and an **average price of $33,355.00**, 32.4% of 2021 Toyota SIennas for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2021 Toyota Sienna 4.46 / 5 stars. - **73.9% of 2021 Sienna models on CarGurus are accident free.** - The 2021 Toyota Sienna features a new hybrid powertrain, which provides superior fuel efficiency, a spacious interior, and enhanced driving comfort. ## Why it stands out The 2021 Toyota Sienna makes a notable mark in the minivan segment with its introduction of a standard hybrid powertrain, making it the first minivan from Toyota to offer such technology. Built on the Toyota New Global Architecture (TNGA-K), the Sienna not only boosts fuel efficiency but also enhances handling. This model achieves impressive EPA ratings of 36 mpg in city, highway, and combined driving for front-wheel-drive configurations. One of the standout features of the Sienna is its spacious and well-designed interior, accommodating passengers comfortably in both the second and third rows. With generous cargo space that includes the ability to carry a full four-by-eight sheet of plywood, this minivan is tailored for utility. Equipped with advanced connectivity features, it showcases a nine-inch touchscreen, Apple CarPlay, Android Auto, and various USB ports, ensuring tech-savvy families are well catered for. While some critics point to a lack of spirited acceleration and minor concerns regarding interior material quality, many users appreciate the overall ride quality and interior versatility. The 2021 Sienna stands out as one of the best options for families in need of a functional and efficient vehicle. ## Other model years to consider - **[2016 Toyota Sienna](https://www.cargurus.com/Cars/l-Used-2016-Toyota-Sienna-c25379)** - Average price: $16,254.00 - Good/great deal percentage: 34.0% - User rating: 4.73 / 5 - Total listings: 1,130 - **[2020 Toyota Sienna](https://www.cargurus.com/Cars/l-Used-2020-Toyota-Sienna-c29072)** - Average price: $27,239.00 - Good/great deal percentage: 32.5% - User rating: 4.9 / 5 - Total listings: 1,100 - **[2024 Toyota Sienna](https://www.cargurus.com/Cars/l-Used-2024-Toyota-Sienna-c33140)** - Average price: $41,385.00 - Good/great deal percentage: 29.4% - User rating: 4.5 / 5 - Total listings: 2,017 This analysis is based on CarGurus' proprietary market data from March 20, 2026, CarGurus experts' opinions, and generative AI.