Used 2021 Mercedes-Benz E-Class for Sale near Colorado
118 results
CarGurus Analysis:
2021 Mercedes-Benz E-Class
With 879 currently listed for sale and an average price of $39,567.00, 31.4% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
75.8% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class stands out with its impressive combination of luxury, performance, and cutting-edge technology.
CarGurus Analysis: 2021 Mercedes-Benz E-Class
overall
Summary
With 879 currently listed for sale and an average price of $39,567.00, 31.4% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz E-Class 4.7 / 5 stars.
75.8% of 2021 E-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz E-Class stands out with its impressive combination of luxury, performance, and cutting-edge technology.
Why it stands out
The 2021 Mercedes-Benz E-Class showcases an exceptional blend of luxury, performance, and practicality. With several body styles and powertrains available, including a hybrid inline-six engine, it's versatile enough to cater to a wide range of buyers. The mid-cycle update for this model year has enhanced its infotainment system and exterior styling, making it more appealing than ever. The E-Class is praised not only for its luxurious and spacious cabin, featuring high-quality materials and advanced technology, but also for its safety features, earning it high marks in crash testing. Despite some concerns about certain advanced features not being standard, the overall package remains compelling for those seeking an elegant and capable vehicle that can excel in both performance and comfort.
Other model years to consider
- Average price: $41,855.00
- Good/great deal percentage: 33.4%
- User rating: 5 / 5
- Total listings: 1,051
- Average price: $30,068.00
- Good/great deal percentage: 31.0%
- User rating: 5 / 5
- Total listings: 998
- Average price: $23,349.00
- Good/great deal percentage: 31.1%
- User rating: 4.76 / 5
- Total listings: 1,435
This analysis is based on CarGurus' proprietary market data from April 27, 2026, CarGurus experts' opinions, and generative AI.
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2026 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Sitting squarely in the midsize luxury sedan segment, the 2026 Mercedes-Benz E-Class competes with the BMW 5 Series, the Audi A6, and the Lexus ES.
2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
Thoroughly updated last year, the Mercedes-Benz E-Class returns for 2025 with added safety equipment, a new entry-level trim, and an AMG E 53 Hybrid version designed to deliver equal parts performance and efficiency.
4.7 Overall rating
Filter by rating
ayekun j
Reviewed a 2021 Mercedes-Benz E 350 4MATIC on Mar 2, 2026
Johnson Ayekun, Best car money can buy,the E350 is in a class of excellent beautiful inside and out side,slik design, elegance meet with performance
Teddi R
Reviewed a 2021 Mercedes-Benz E-Class on Jun 2, 2024
You cant go wrong with any of the E-class Mercedes! They are bulletproof cars with NO issues.
Anonymous
Reviewed a 2021 Mercedes-Benz E-Class on May 2, 2024
Ive owned many Mercedes over the years but always come back to Model E. Best size, forward technology and usually handsome exterior/interior
Heather S
Reviewed a 2021 Mercedes-Benz E-Class on Jan 9, 2026
I love all the features, still learning a lot about them. I would seriously suggest reading the owners manual or watching some how to videos.
2021 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| AMG E 53 Coupe 4MATIC | $76,250 |
| AMG E 63 S Wagon 4MATIC | $112,450 |
| E 450 4MATIC Coupe AWD | $67,450 |
| E 450 4MATIC Sedan AWD | $62,000 |
| AMG E 63 S Sedan 4MATIC | $107,500 |
| AMG 53 E Sedan 4MATIC | $73,900 |
| E 350 4MATIC | $56,750 |
| E 350 RWD | $54,250 |
2021 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz E-Class prices has changed over time.
See more price trends
