Used 2021 Ford F-250 Super Duty for SaleNationwide

Filters (3)

Location:

Include delivery listings?

3,627 vehicles found

Shop with transparent pricing.

Only show listings that include dealer fees
Year:
2022
Make:
Ford
Model:
F-250 Super Duty
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.7L V8 Biodiesel
Exterior color:
Gray
Fuel type:
Biodiesel
Transmission:
Automatic
Mileage:
55,728
Stock #:
6104A
VIN:
1FT7W2BT3NEG07942
Gray 2022 Ford F-250 Super Duty Pickup Truck Four-Wheel Drive Automatic
New arrival

 

2022 Ford F-250 Super Duty

Lariat Crew Cab 4WD

55,728 mi

Marshall, TX
Good Deal

$60,215

Year:
2022
Make:
Ford
Model:
F-250 Super Duty
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Exterior color:
Silver
Mileage:
36,733
Stock #:
X6979
VIN:
1FT7W2BN6NEG03188
Silver 2022 Ford F-250 Super Duty Pickup Truck Four-Wheel Drive
New arrival

 

2022 Ford F-250 Super Duty

XL Crew Cab 4WD

36,733 mi

Norman, OK
Good Deal

$43,697

Year:
2022
Make:
Ford
Model:
F-250 Super Duty
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
7.3L V8
Exterior color:
Agate Black/Stone Gray
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
50,000
Stock #:
26-UT44
VIN:
1FT7W2BN0NEF25572
Agate Black/Stone Gray 2022 Ford F-250 Super Duty Pickup Truck Four-Wheel Drive Automatic
New arrival

 

2022 Ford F-250 Super Duty

Lariat Crew Cab 4WD

50,000 mi

Schuyler, NE
Great Deal
Manufacturer certified

$49,900

Year:
2021
Make:
Ford
Model:
F-250 Super Duty
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Exterior color:
Gray Metallic
Interior color:
Medium Earth Gray
Transmission:
Automatic
Mileage:
143,716
Stock #:
12072B
VIN:
1FT7W2BN9MEE12072
Gray Metallic 2021 Ford F-250 Super Duty Pickup Truck Four-Wheel Drive Automatic
Price drop

-$3,499

 

2021 Ford F-250 Super Duty

XLT Crew Cab 4WD

143,716 mi

Cherry Hill, NJ
Good Deal

$33,413

$30,513

Year:
2021
Make:
Ford
Model:
F-250 Super Duty
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Exterior color:
Oxford White
Interior color:
Medium Earth Gray
Transmission:
Automatic
Mileage:
85,978
Stock #:
HP0754A
VIN:
1FT7W2BN8MED75922
Oxford White 2021 Ford F-250 Super Duty Pickup Truck Four-Wheel Drive Automatic

 

2021 Ford F-250 Super Duty

XL Crew Cab 4WD

85,978 mi

Rome, GA
Fair Deal

$35,864

Year:
2022
Make:
Ford
Model:
F-250 Super Duty
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.7L V8 Biodiesel
Exterior color:
Oxford White
Fuel type:
Biodiesel
Interior color:
Medium Earth Gray
Transmission:
Automatic
Mileage:
84,432
Stock #:
15293
VIN:
1FT8W2BT8NEF63845
Oxford White 2022 Ford F-250 Super Duty Pickup Truck Four-Wheel Drive Automatic
Price drop

-$3,500

 

2022 Ford F-250 Super Duty

XL Crew Cab 4WD

84,432 mi

Grand Junction, CO
Good Deal

$43,494

$39,994

Year:
2020
Make:
Ford
Model:
F-250 Super Duty
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
7.3L V8
Exterior color:
Black
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
Automatic
Mileage:
81,408
Stock #:
7303
VIN:
1FT7W2BN4LEE02368
Black 2020 Ford F-250 Super Duty Pickup Truck Four-Wheel Drive Automatic

 

2020 Ford F-250 Super Duty

XLT Crew Cab 4WD

81,408 mi

Norwich, CT
Fair Deal

$37,749

CarGurus Analysis:

2021 Ford F-250 Super Duty

4.5

  • With 3,583 currently listed for sale and an average price of $46,484, 29.6% of 2021 Ford F-250 Super Dutys for sale on CarGurus are rated as good or great deals.

  • Favorably reviewed: Owners rated the 2021 Ford F-250 Super Duty 4.5 / 5 stars and CarGurus experts gave it a 6.33 / 10.

  • 79.0% of 2021 F-250 Super Duty models on CarGurus are accident free.

Research summarized using AI

Year:
2020
Make:
Ford
Model:
F-250 Super Duty
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.7L V8 Biodiesel
Exterior color:
Black
Fuel type:
Biodiesel
Interior color:
Brown
Transmission:
Automatic
Mileage:
134,763
Stock #:
D16166
VIN:
1FT7W2BT2LED16166
Black 2020 Ford F-250 Super Duty Pickup Truck Four-Wheel Drive Automatic

 

2020 Ford F-250 Super Duty

King Ranch Crew Cab 4WD

134,763 mi

Hattiesburg, MS
Good Deal

$49,989

Year:
2020
Make:
Ford
Model:
F-250 Super Duty
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.7L V8 Biodiesel
Exterior color:
Oxford White
Fuel type:
Biodiesel
Interior color:
Black
Transmission:
Automatic
Mileage:
13,372
Stock #:
LEE96761
VIN:
1FT8W2BTXLEE96761
Oxford White 2020 Ford F-250 Super Duty Pickup Truck Four-Wheel Drive Automatic
New arrival

 

2020 Ford F-250 Super Duty

Lariat Crew Cab 4WD

13,372 mi

Livingston, TX
Good Deal

$58,470

Year:
2022
Make:
Ford
Model:
F-250 Super Duty
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
7.3L V8
Exterior color:
Star White Metallic Tri-Coat
Fuel type:
Gasoline
Interior color:
BLACK ONYX
Transmission:
6-Speed Automatic
Mileage:
57,305
Stock #:
22063A
VIN:
1FT7W2BN7NEC08310
Star White Metallic Tri-Coat 2022 Ford F-250 Super Duty Pickup Truck Four-Wheel Drive 6-Speed Automatic
Price drop

-$1,913

 

2022 Ford F-250 Super Duty

Lariat Crew Cab 4WD

57,305 mi

Lawrenceville, GA
Good Deal

$53,678

$51,765

Year:
2021
Make:
Ford
Model:
F-250 Super Duty
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
7.3L V8
Exterior color:
Velocity Blue
Fuel type:
Gasoline
Interior color:
Medium Earth Gray
Transmission:
Automatic
Mileage:
63,671
Stock #:
XZ228A
VIN:
1FT7W2BN5MED27875
Velocity Blue 2021 Ford F-250 Super Duty Pickup Truck Four-Wheel Drive Automatic

 

2021 Ford F-250 Super Duty

XLT Crew Cab 4WD

63,671 mi

Greenville, PA
Good Deal

$41,388

Year:
2022
Make:
Ford
Model:
F-250 Super Duty
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Exterior color:
Rapid Red Metallic Tinted Clearcoat
Interior color:
Medium Earth Gray
Transmission:
Automatic
Mileage:
29,912
Stock #:
1H2559
VIN:
1FT7W2BN5NED69917
Rapid Red Metallic Tinted Clearcoat 2022 Ford F-250 Super Duty Pickup Truck Four-Wheel Drive Automatic

 

2022 Ford F-250 Super Duty

XLT Crew Cab 4WD

29,912 mi

Hickory, NC
Fair Deal

$49,258

Year:
2022
Make:
Ford
Model:
F-250 Super Duty
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Exterior color:
Oxford White
Interior color:
Black Onyx
Transmission:
Automatic
Mileage:
96,509
Stock #:
NEE97592
VIN:
1FT7W2BN7NEE97592
Oxford White 2022 Ford F-250 Super Duty Pickup Truck Four-Wheel Drive Automatic

 

2022 Ford F-250 Super Duty

Lariat Crew Cab 4WD

96,509 mi

Weimar, TX
Good Deal

$44,767

CarGurus Analysis: 2021 Ford F-250 Super Duty

6.3
of 10
overall
Look and feel7/10
Technology6/10
Performance8/10
Safety5/10
Form & function8/10
Cost effectiveness4/10
Image Not Available

Summary

  • With 3,583 currently listed for sale and an average price of $46,484, 29.6% of 2021 Ford F-250 Super Dutys for sale on CarGurus are rated as good or great deals.

  • Favorably reviewed: Owners rated the 2021 Ford F-250 Super Duty 4.5 / 5 stars and CarGurus experts gave it a 6.33 / 10.

  • 79.0% of 2021 F-250 Super Duty models on CarGurus are accident free.

Why it stands out

The 2021 Ford F-250 Super Duty stands out as a heavy-duty pickup built around serious capability. Ford positions the Super Duty line for buyers who need hardcore truck performance, and the F-250 is offered with multiple body styles and multiple powertrain options. It is also available only in a single-rear-wheel setup, which helps define its role within the lineup.

That strength comes with some tradeoffs. The truck’s power is a clear highlight, and owners commonly praise its solid performance and powerful 6.7 turbocharged diesel engine. At the same time, the F-250 is not trying to hide its heavy-duty character: the ride quality is poor, handling is poor, and the interior materials feel cheap. Some drivers also note that the 10-speed transmission can take some getting used to.

For buyers who want a truck that emphasizes capability over comfort, the 2021 Ford F-250 Super Duty has a straightforward appeal. It offers the kind of size, power, and configuration flexibility that make sense for demanding work, while its drawbacks are the familiar compromises of a truck focused on strength first.

Other model years to consider

This analysis is based on CarGurus' proprietary market data from September 7, 2026, CarGurus experts' opinions, and generative AI.

Read full review

*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.

Relevant articles

A better way to discover your best deal

Let us help you find a car you’ll love.