Used 2021 GMC Sierra 2500HD for Sale Nationwide
1,698 results
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- 4X2
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 106,643
- Stock #:
- MF160381
- VIN:
- 1GT48LE77MF160381
-$695
2021 GMC Sierra 2500HD
Base Crew Cab RWD
106,643 mi
$30,838
$30,143
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Fuel type:
- Gasoline
- Transmission:
- 6-Speed Automatic
- Mileage:
- 42,728
- Stock #:
- G26192A
- VIN:
- 1GT59LE75NF254715
2022 GMC Sierra 2500HD
Pro Double Cab 4WD
42,728 mi
$36,950
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 94,372
- Stock #:
- R1171A
- VIN:
- 1GT49ME73LF187224
2020 GMC Sierra 2500HD
SLE Crew Cab 4WD
94,372 mi
$32,253
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Quicksilver Metallic
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 54,644
- Stock #:
- 3479
- VIN:
- 1GT29ME75NF207631
2022 GMC Sierra 2500HD
SLE Double Cab 4WD
54,644 mi
$38,080
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Red Quartz Tintcoat
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 56,791
- Stock #:
- 2053207A
- VIN:
- 1GT19ME71LF253207
2020 GMC Sierra 2500HD
SLE Crew Cab 4WD
56,791 mi
$39,303
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Black
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 111,798
- Stock #:
- 6GM0518T
- VIN:
- 1GT49NE79LF113943
2020 GMC Sierra 2500HD
SLT Crew Cab 4WD
111,798 mi
$38,592
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 195,087
- Stock #:
- R182401
- VIN:
- 1GT59LE78MF277064
2021 GMC Sierra 2500HD
Double Cab 4WD
195,087 mi
$23,294
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Blue
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- 6-Speed Automatic
- Mileage:
- 78,205
- Stock #:
- T18316
- VIN:
- 1GT29ME75MF230633
2021 GMC Sierra 2500HD
SLE Double Cab 4WD
78,205 mi
$33,998
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 134,816
- Stock #:
- TK9322
- VIN:
- 1GD49LE7XMF199197
2021 GMC Sierra 2500HD
Base Crew Cab LB 4WD
134,816 mi
$28,900
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Quicksilver Metallic
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 142,664
- Stock #:
- T22342A
- VIN:
- 1GT49NE73LF154696
2020 GMC Sierra 2500HD
SLT Crew Cab 4WD
142,664 mi
$32,026
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Carbon Black Metallic
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 101,473
- Stock #:
- XJ9701B
- VIN:
- 1GT49REY4LF206076
2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
101,473 mi
$47,499
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Quicksilver Metallic
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 15,101
- Stock #:
- N0984A
- VIN:
- 1GT49LE72NF278594
2022 GMC Sierra 2500HD
Pro Crew Cab 4WD
15,101 mi
$40,187
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Summit White
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 80,739
- Stock #:
- G4117A
- VIN:
- 1GT49NEY5MF216707
2021 GMC Sierra 2500HD
SLT Crew Cab 4WD
80,739 mi
$48,989
CarGurus Analysis:
2021 GMC Sierra 2500HD
With 1,681 currently listed for sale and an average price of $51,642.00, 31.8% of 2021 GMC Sierras 2500HD for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
79.4% of 2021 Sierra 2500HD models on CarGurus are accident free.
The 2021 GMC Sierra 2500HD stands out for its upscale features compared to competitors, providing a more luxurious interior and advanced technology options.
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- 4X2
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Jet Black, Vinyl seat trim
- Transmission:
- Automatic
- Mileage:
- 70,509
- Stock #:
- T1880F
- VIN:
- 1GT58LE70MF234812
-$1,891
2021 GMC Sierra 2500HD
Double Cab RWD
70,509 mi
$32,680
$30,789
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Black (Ebony Twilight Metallic)
- Fuel type:
- Gasoline
- Interior color:
- Jet Black With Kalahari Accents
- Transmission:
- 6-Speed Automatic
- Mileage:
- 89,170
- Stock #:
- 26190A
- VIN:
- 1GT49PE75NF230255
2022 GMC Sierra 2500HD
AT4 Crew Cab 4WD
89,170 mi
$48,300
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 163,208
- Stock #:
- 5130A
- VIN:
- 1GT49REY6LF108313
2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
163,208 mi
$41,675
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Gray (Dark Sky Metallic)
- Fuel type:
- Biodiesel
- Interior color:
- Gray (Dark Walnut/Dark Ash Grey)
- Transmission:
- Automatic
- Mileage:
- 43,002
- Stock #:
- LF198594
- VIN:
- 1GT49REY6LF198594
2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
43,002 mi
$53,999
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Summit White
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 229,234
- Stock #:
- LF201972
- VIN:
- 1GT49REY7LF201972
2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
229,234 mi
$29,995
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Quicksilver Metallic
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 96,600
- Stock #:
- 308822-TR-109
- VIN:
- 1GT49MEY2MF308822
2021 GMC Sierra 2500HD
SLE Crew Cab 4WD
96,600 mi
$39,950
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Onyx Black
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 84,360
- Stock #:
- AG8936
- VIN:
- 1GT49RE79NF163588
2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
84,360 mi
$50,485
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Fuel type:
- Gasoline
- Transmission:
- 6-Speed Automatic
- Mileage:
- 74,436
- Stock #:
- 353999
- VIN:
- 1GT59LE73NF353999
2022 GMC Sierra 2500HD
Pro Double Cab 4WD
74,436 mi
$35,797
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- White Frost Tricoat
- Fuel type:
- Biodiesel
- Interior color:
- Gray (Dark Walnut/Dark Ash Grey)
- Transmission:
- Automatic
- Mileage:
- 85,355
- Stock #:
- 293742V
- VIN:
- 1GT49REYXLF293742
2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
85,355 mi
$55,227
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 32,470
- Stock #:
- FN6807A
- VIN:
- 1GT59ME76NF130443
2022 GMC Sierra 2500HD
SLE Double Cab 4WD
32,470 mi
$44,580
CarGurus Analysis: 2021 GMC Sierra 2500HD
Summary
With 1,681 currently listed for sale and an average price of $51,642.00, 31.8% of 2021 GMC Sierras 2500HD for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
79.4% of 2021 Sierra 2500HD models on CarGurus are accident free.
The 2021 GMC Sierra 2500HD stands out for its upscale features compared to competitors, providing a more luxurious interior and advanced technology options.
Why it stands out
The 2021 GMC Sierra 2500HD is a notable choice among heavy-duty trucks thanks to its combination of rugged capabilities and upscale amenities. This model year continues the trend of offering premium features that differentiate it from its Chevy Silverado counterpart, appealing to buyers looking for both utility and comfort. The Sierra comes equipped with technology designed for modern drivers, emphasizing connectivity and safety. With a strong performance profile, including options for a powerful diesel engine, the Sierra 2500HD is well-suited for demanding tasks, from heavy towing to off-road adventures. While it shines in many areas, potential buyers should be mindful of its higher price point compared to rivals, as well as reported issues in some earlier model years, ensuring they choose a well-maintained example.
Other model years to consider
- Average price: $76,111.00
- Good/great deal percentage: 33.9%
- User rating: 5 / 5
- Total listings: 3,931
- Average price: $69,916.00
- Good/great deal percentage: 33.4%
- User rating: 4 / 5
- Total listings: 4,151
- Average price: $49,909.00
- Good/great deal percentage: 30.4%
- User rating: 4.86 / 5
- Total listings: 1,160
This analysis is based on CarGurus' proprietary market data from June 15, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles
2026 GMC Sierra 2500HD Pricing, Specs, and Release Date
Aside from a freshened color palette and broader availability of the trick MultiPro Tailgate, the 2026 GMC Sierra 2500HD full-size pickup truck soldiers on as a premium workhorse capable of towing up to 20,000 pounds in luxurious style.
2025 GMC Sierra 2500HD Pricing, Specs, and Release Date
Slotted between the light-duty 1500 and the ultra-tough 3500HD, the 2025 GMC Sierra 2500HD balances immense capability with the comfort and latest amenities expected from today's truck buyers. Upgrades for 2025 include a newly standard trailer brake controller.
Who Makes GMC Cars?
GMC is an American automaker that builds premium trucks and SUVs with capability and comfort as selling points. GMC is a division of General Motors and all of its vehicles share platforms with other GM products. Certain products, like its trucks, are very closely related to Chevrolet products.
5.0 Overall rating
Filter by rating
Allan K
Reviewed a 2021 GMC Sierra 2500HD on Jan 18, 2021
-Excellent trailering mirrors with lights, allow increased visibility when backing up at night -Engine noise is relatively quiet compared to older diesel pick ups, can order at fast food drive throughs without shutting engine off -Fuel economy is good for a vehicle of this size (I have 3500HD, not 2500HD) -Driver safety features and various camera views are very helpful -Trim version for this review is Denali, with power running boards, really not missing anything significant
Anonymous
Reviewed a 2021 GMC Sierra 2500HD on Sep 3, 2022
An absolutely beautiful pickup ! Handles & rides exceptionally well !! Nobody will regret making the decision to purchase this awesome truck .
jordyn c
Reviewed a 2021 GMC AT4 Crew Cab 4WD on Dec 4, 2023
This car is not missing nothing at all it is perfect
Kevin K
Reviewed a 2021 GMC Sierra 2500HD on Apr 21, 2022
So far we are very happy.We appreciate the options and layout
2021 GMC Sierra 2500HD Trims
| Trim type | MSRP |
|---|---|
| LB 4WD | $39,000 |
| Double Cab 4WD | $41,600 |
| SLE Double Cab 4WD | $46,400 |
| Base Crew Cab 4WD | $43,400 |
| SLT Crew Cab 4WD | $56,200 |
| SLE Crew Cab 4WD | $48,200 |
| AT4 Crew Cab 4WD | $59,100 |
| Denali Crew Cab 4WD | $65,500 |
2021 GMC Sierra 2500HD Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 GMC Sierra 2500HD prices has changed over time.
See more price trends2021 GMC Sierra 2500HD Pricing Analysis
Pricing by Popular US Cities
Market Area: Nationwide
Key Insights
- Highest Prices in Los Angeles: The Los Angeles, CA market ($59,004) ranks as the most expensive, likely reflecting demand in an urban environment, coupled with a limited inventory of new models.
- Lowest Prices in Dallas: Conversely, Dallas, TX ($49,614) shows the cheapest average, suggesting greater inventory levels or more competitive pricing strategies.
- Consistent Demand Across Major Urban Areas: Cities like Chicago and Philadelphia exhibit similar pricing patterns (around $55,990 and $50,012, respectively), indicating stable demand for the model across these regions.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Los Angeles, CA | 129 | $59,004 |
| Chicago, IL | 224 | $55,990 |
| Philadelphia, PA | 209 | $50,012 |
| New York, NY | 197 | $50,964 |
| Miami, FL | 157 | $57,245 |
| Dallas, TX | 226 | $49,614 |
| Houston, TX | 222 | $51,047 |
| Atlanta, GA | 249 | $54,305 |
| Boston, MA | 202 | $52,576 |
| Washington, DC | 200 | $49,067 |
Pricing Analysis by Model Year
Key Insights
- Significant Premium for Newer Models: The 2026 GMC Sierra 2500HD is currently priced at $85,450, nearly 81.6% above MSRP, indicating strong demand for new models in the heavy-duty truck segment.
- Depreciation Trends Observed: Older model years, such as the 2014 model, show a sharp decline with an average price of $24,916, suggesting significant depreciation of around 20% compared to MSRP.
- Mid-Year Models Provide Solid Value: The 2021 model year offers a balanced pricing position, reflecting moderate depreciation trends that may appeal to shoppers looking for value without high depreciation.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 GMC Sierra 2500HD | $47,000 | $85,450 | +81.6% |
| 2025 GMC Sierra 2500HD | $46,300 | $76,249 | +64.6% |
| 2024 GMC Sierra 2500HD | $45,400 | $69,293 | +52.8% |
| 2023 GMC Sierra 2500HD | $42,200 | $56,153 | +33.1% |
| 2022 GMC Sierra 2500HD | $36,200 | $52,644 | +45.4% |
| 2020 GMC Sierra 2500HD | $35,800 | $49,549 | +38.3% |
| 2019 GMC Sierra 2500HD | $38,200 | $40,489 | +6.0% |
| 2018 GMC Sierra 2500HD | $35,000 | $38,548 | +10.3% |
| 2017 GMC Sierra 2500HD | $34,190 | $36,481 | +6.7% |
| 2016 GMC Sierra 2500HD | $33,535 | $32,917 | -1.8% |
| 2015 GMC Sierra 2500HD | $33,195 | $29,812 | -10.2% |
| 2014 GMC Sierra 2500HD | $31,310 | $24,916 | -20.4% |
These recommendations are based on CarGurus' proprietary market data from June 11, 2026, CarGurus experts' opinions, and generative AI.
