Used 2021 GMC Sierra 2500HD for Sale Nationwide
1,680 results
CarGurus Analysis:
2021 GMC Sierra 2500HD
With 1,637 currently listed for sale and an average price of $52,038.00, 29.0% of 2021 GMC Sierra 2500HDs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
77.8% of 2021 Sierra 2500HD models on CarGurus are accident-free.
The 2021 GMC Sierra 2500HD boasts a stylish design, a well-equipped cabin, and modern technology, making it a strong contender in the heavy-duty truck market.
CarGurus Analysis: 2021 GMC Sierra 2500HD

Summary
With 1,637 currently listed for sale and an average price of $52,038.00, 29.0% of 2021 GMC Sierra 2500HDs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
77.8% of 2021 Sierra 2500HD models on CarGurus are accident-free.
The 2021 GMC Sierra 2500HD boasts a stylish design, a well-equipped cabin, and modern technology, making it a strong contender in the heavy-duty truck market.
Why it stands out
The 2021 GMC Sierra 2500HD is designed to deliver a blend of capability and luxury that is appealing to both work and leisure users. As a heavy-duty pickup, it stands out with its upscale design and finishes, aligning with GMC's "Professional Grade" branding. The Sierra 2500HD is equipped with a range of the latest technology and comfort features that enhance the driving experience, particularly in comparison to some competitors which may lack these advancements. The truck offers powerful engine options, a spacious and comfortable interior, and various trims, including the luxurious Denali model which emphasizes premium features. Plus, with 77.8% of models being accident-free, it is a solid choice for buyers concerned about reliability and safety. Overall, the 2021 model successfully combines robust performance with modern amenities, making it an attractive option in the heavy-duty truck segment.
Other model years to consider
- Average price: $56,541.00
- Good/great deal percentage: 31.1%
- User rating: 4 / 5
- Total listings: 3,526
- Average price: $70,020.00
- Good/great deal percentage: 31.7%
- User rating: 4 / 5
- Total listings: 4,072
- Average price: $76,700.00
- Good/great deal percentage: 31.6%
- User rating: 5 / 5
- Total listings: 3,760
This analysis is based on CarGurus' proprietary market data from June 1, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles

2026 GMC Sierra 2500HD Pricing, Specs, and Release Date
Aside from a freshened color palette and broader availability of the trick MultiPro Tailgate, the 2026 GMC Sierra 2500HD full-size pickup truck soldiers on as a premium workhorse capable of towing up to 20,000 pounds in luxurious style.

2025 GMC Sierra 2500HD Pricing, Specs, and Release Date
Slotted between the light-duty 1500 and the ultra-tough 3500HD, the 2025 GMC Sierra 2500HD balances immense capability with the comfort and latest amenities expected from today's truck buyers. Upgrades for 2025 include a newly standard trailer brake controller.

Who Makes GMC Cars?
GMC is an American automaker that builds premium trucks and SUVs with capability and comfort as selling points. GMC is a division of General Motors and all of its vehicles share platforms with other GM products. Certain products, like its trucks, are very closely related to Chevrolet products.
5.0 Overall rating
Filter by rating
Allan K
Reviewed a 2021 GMC Sierra 2500HD on Jan 18, 2021
-Excellent trailering mirrors with lights, allow increased visibility when backing up at night -Engine noise is relatively quiet compared to older diesel pick ups, can order at fast food drive throughs without shutting engine off -Fuel economy is good for a vehicle of this size (I have 3500HD, not 2500HD) -Driver safety features and various camera views are very helpful -Trim version for this review is Denali, with power running boards, really not missing anything significant
Anonymous
Reviewed a 2021 GMC Sierra 2500HD on Sep 3, 2022
An absolutely beautiful pickup ! Handles & rides exceptionally well !! Nobody will regret making the decision to purchase this awesome truck .
jordyn c
Reviewed a 2021 GMC AT4 Crew Cab 4WD on Dec 4, 2023
This car is not missing nothing at all it is perfect
Kevin K
Reviewed a 2021 GMC Sierra 2500HD on Apr 21, 2022
So far we are very happy.We appreciate the options and layout
2021 GMC Sierra 2500HD Trims
| Trim type | MSRP |
|---|---|
| LB RWD | $36,200 |
| Double Cab 4WD | $41,600 |
| SLE Double Cab 4WD | $46,400 |
| Base Crew Cab 4WD | $43,400 |
| SLE Crew Cab 4WD | $48,200 |
| SLT Crew Cab 4WD | $56,200 |
| AT4 Crew Cab 4WD | $59,100 |
| Denali Crew Cab 4WD | $65,500 |
2021 GMC Sierra 2500HD Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 GMC Sierra 2500HD prices has changed over time.
See more price trends2021 GMC Sierra 2500HD Pricing Analysis
Pricing by Popular US Cities
Market Area: Nationwide
Key Insights
- Highest Prices in Los Angeles: The average price in Los Angeles, CA ($60,947) reflects a strong demand in the urban market, likely due to a combination of lifestyle preferences and vehicle utility needs.
- Lowest Prices in Philadelphia: Philadelphia, PA ($45,269) offers the lowest average pricing, suggesting a more cost-sensitive market or potentially greater availability of lower-priced vehicles.
- Inventory Distribution: Cities like Atlanta, GA (256 listings) and Dallas, TX (229 listings) have robust inventories, indicating stable supply which contributes to moderate pricing levels.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Los Angeles, CA | 132 | $60,947 |
| New York, NY | 199 | $51,473 |
| Chicago, IL | 233 | $55,540 |
| Dallas, TX | 229 | $48,941 |
| Philadelphia, PA | 211 | $45,269 |
| Houston, TX | 232 | $48,848 |
| Miami, FL | 168 | $54,763 |
| Washington, DC | 211 | $49,472 |
| Atlanta, GA | 256 | $54,703 |
| Boston, MA | 205 | $50,889 |
Pricing Analysis by Model Year
Key Insights
- Significant Premium on New Models: The 2026 GMC Sierra 2500HD is priced at $85,341, approximately 81.2% above its original MSRP, reflecting strong demand and limited availability.
- Steep Depreciation in Earlier Years: The 2014 model shows the most depreciation, valued at -21.0% below MSRP, highlighting the depreciation trend typical for older model years.
- Best Value from 2020-2022 Models: Prices for the 2022 model are relatively stable at $52,836, only -0.7% below MSRP, making it an attractive option for buyers looking for recent models at a lower price point.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 | $47,000 | $85,341 | +81.2% |
| 2025 | $46,300 | $76,688 | +65.5% |
| 2024 | $45,400 | $69,600 | +53.2% |
| 2023 | $42,200 | $56,373 | +33.6% |
| 2022 | $36,200 | $52,836 | -0.7% |
| 2021 | $35,800 | $49,704 | +38.9% |
| 2020 | $38,200 | $40,430 | +5.8% |
| 2019 | $35,000 | $39,686 | +13.7% |
| 2018 | $34,190 | $36,118 | +5.4% |
| 2017 | $33,535 | $33,586 | +0.2% |
| 2016 | $33,195 | $29,672 | -10.6% |
| 2014 | $31,310 | $24,740 | -21.0% |
These recommendations are based on CarGurus' proprietary market data from June 4, 2026, CarGurus experts' opinions, and generative AI.








