Used 2021 GMC Sierra 2500HD for Sale near Los Angeles, CA
137 results
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- White Frost Tricoat
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 25,201
- Stock #:
- 39782A
- VIN:
- 1GT49REYXMF153806


Sponsored by Antelope Valley Chevrolet
2021 GMC Sierra 2500HD
Denali Crew Cab 4WD
25,201 mi
$66,996
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- White Frost Tricoat
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 26,108
- Stock #:
- 61123
- VIN:
- 1GT49REY7LF228234

Sponsored Listing
2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
26,108 mi
$61,080
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Pacific Blue Metallic
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 27,654
- Stock #:
- 260660A
- VIN:
- 1GT49RE78NF353429

Sponsored Listing
2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
27,654 mi
$62,996
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- White
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 29,642
- Stock #:
- 28268960
- VIN:
- 1GT49RE71NF288598

2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
29,642 mi
$61,997
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Summit White
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- 10-Speed Automatic
- Mileage:
- 60,599
- Stock #:
- 333443
- VIN:
- 1GT49MEY7NF333443

2022 GMC Sierra 2500HD
SLE Crew Cab LB 4WD
60,599 mi
$47,894
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- 4X2
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 87,412
- Stock #:
- 1308
- VIN:
- 1GT58LE74NF271685

2022 GMC Sierra 2500HD
Pro Double Cab RWD
87,412 mi
$27,500
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Pacific Blue Metallic
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 27,654
- Stock #:
- 260660A
- VIN:
- 1GT49RE78NF353429

2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
27,654 mi
$62,996
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Summit White
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black With Kalahari Accents
- Transmission:
- Automatic
- Mileage:
- 64,372
- Stock #:
- C263016A
- VIN:
- 1GT49PEYXNF305248
Preparing for a close up...
Photos coming soon
2022 GMC Sierra 2500HD
AT4 Crew Cab 4WD
64,372 mi
$55,998
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- 4X2
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 53,888
- Stock #:
- 61264
- VIN:
- 1GT48ME79NF231913

2022 GMC Sierra 2500HD
SLE Crew Cab RWD
53,888 mi
$39,080
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Onyx Black
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black With Kalahari Accents
- Transmission:
- Automatic
- Mileage:
- 117,769
- Stock #:
- XF190708
- VIN:
- 1GT49PEY0NF190708

2022 GMC Sierra 2500HD
AT4 Crew Cab 4WD
117,769 mi
$48,072
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Summit White
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black With Kalahari Accents
- Transmission:
- Automatic
- Mileage:
- 49,466
- Stock #:
- C228284A
- VIN:
- 1GT49PEY1NF228284
Preparing for a close up...
Photos coming soon
2022 GMC Sierra 2500HD
AT4 Crew Cab 4WD
49,466 mi
$57,998
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Quicksilver Metallic
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 52,874
- Stock #:
- T241630
- VIN:
- 1GT49ME79MF241630

2021 GMC Sierra 2500HD
SLE Crew Cab 4WD
52,874 mi
$45,617
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Forest Metallic
- Fuel type:
- Biodiesel
- Interior color:
- Dark Walnut/Slate
- Transmission:
- Automatic
- Mileage:
- 84,640
- Stock #:
- LOP22491
- VIN:
- 1GT49NEY1NF217242

2022 GMC Sierra 2500HD
SLT Crew Cab 4WD
84,640 mi
$52,139
CarGurus Analysis:
2021 GMC Sierra 2500HD
With 137 currently listed for sale near Los Angeles, CA and an average price of $54,575.00, 10.9% of 2021 GMC Sierras 2500HD for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
80.3% of 2021 Sierra 2500HD models on CarGurus are accident free.
The 2021 GMC Sierra 2500HD is known for its robust build and offers an upscale design compared to its competitors, featuring advanced technology and comfort features akin to those found in lighter-duty models.
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- White
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 139,311
- Stock #:
- B3992
- VIN:
- 1GT49LE74LF149284

2020 GMC Sierra 2500HD
Base Crew Cab 4WD
139,311 mi
$29,293
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Black
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- 6-Speed Automatic
- Mileage:
- 108,367
- Stock #:
- 134933
- VIN:
- 1GT49RE79NF134933

2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
108,367 mi
$49,021
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Exterior color:
- Black
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 120,409
- Stock #:
- 149393A
- VIN:
- 1GT49REY0NF149393

2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
120,409 mi
$47,924
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Black
- Fuel type:
- Gasoline
- Interior color:
- Jet Black With Kalahari Accents
- Transmission:
- 6-Speed Automatic
- Mileage:
- 99,804
- Stock #:
- 4928
- VIN:
- 1GT49PE72NF177627

2022 GMC Sierra 2500HD
AT4 Crew Cab 4WD
99,804 mi
$45,998
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Blue
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 86,307
- Stock #:
- 174754
- VIN:
- 1GT49PEY8LF174754

2020 GMC Sierra 2500HD
AT4 Crew Cab 4WD
86,307 mi
$53,027
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- White Frost Tricoat
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 26,108
- Stock #:
- 61123
- VIN:
- 1GT49REY7LF228234

2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
26,108 mi
$61,080
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- White Frost Tricoat
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 25,201
- Stock #:
- 39782A
- VIN:
- 1GT49REYXMF153806

2021 GMC Sierra 2500HD
Denali Crew Cab 4WD
25,201 mi
$66,996
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Black
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 45,997
- Stock #:
- F245994
- VIN:
- 1GT49RE73NF245994

2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
45,997 mi
$55,278
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- White
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 97,493
- Stock #:
- 2025-526
- VIN:
- 1GT49ME77MF311402

2021 GMC Sierra 2500HD
SLE Crew Cab 4WD
97,493 mi
$35,140
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Onyx Black
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black With Kalahari Accents
- Transmission:
- Automatic
- Mileage:
- 49,544
- Stock #:
- 87382
- VIN:
- 1GT49PEY5MF187382

Sponsored Listing
2021 GMC Sierra 2500HD
AT4 Crew Cab 4WD
49,544 mi
$58,007
CarGurus Analysis: 2021 GMC Sierra 2500HD

Summary
With 137 currently listed for sale near Los Angeles, CA and an average price of $54,575.00, 10.9% of 2021 GMC Sierras 2500HD for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
80.3% of 2021 Sierra 2500HD models on CarGurus are accident free.
The 2021 GMC Sierra 2500HD is known for its robust build and offers an upscale design compared to its competitors, featuring advanced technology and comfort features akin to those found in lighter-duty models.
Why it stands out
The 2021 GMC Sierra 2500HD distinguishes itself in the heavy-duty pickup market with its balance of rugged capability and upscale features. As a three-quarter-ton truck, it delivers formidable towing and hauling capacities while presenting a more refined interior compared to rivals like the Ford Super Duty and Ram 2500. Notably, the Sierra 2500HD includes features like advanced infotainment systems, high-quality materials, and spacious cabins that appeal to both contractors and families alike. This model year also maintains a reputation for reliability with a significant portion of its listings being accident-free, further enhancing its appeal. While it offers power and utility, potential buyers should be aware of the associated costs that may exceed those of comparable models.
Other model years to consider
- Average price: $76,726.00
- Good/great deal percentage: 18.2%
- User rating: 5 / 5
- Total listings: 231
- Average price: $75,702.00
- Good/great deal percentage: 21.1%
- User rating: 4 / 5
- Total listings: 237
- Average price: $55,633.00
- Good/great deal percentage: 12.1%
- User rating: 4.86 / 5
- Total listings: 107
This analysis is based on CarGurus' proprietary market data from June 16, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles

2026 GMC Sierra 2500HD Pricing, Specs, and Release Date
Aside from a freshened color palette and broader availability of the trick MultiPro Tailgate, the 2026 GMC Sierra 2500HD full-size pickup truck soldiers on as a premium workhorse capable of towing up to 20,000 pounds in luxurious style.

2025 GMC Sierra 2500HD Pricing, Specs, and Release Date
Slotted between the light-duty 1500 and the ultra-tough 3500HD, the 2025 GMC Sierra 2500HD balances immense capability with the comfort and latest amenities expected from today's truck buyers. Upgrades for 2025 include a newly standard trailer brake controller.

Who Makes GMC Cars?
GMC is an American automaker that builds premium trucks and SUVs with capability and comfort as selling points. GMC is a division of General Motors and all of its vehicles share platforms with other GM products. Certain products, like its trucks, are very closely related to Chevrolet products.
5.0 Overall rating
Filter by rating
Allan K
Reviewed a 2021 GMC Sierra 2500HD on Jan 18, 2021
-Excellent trailering mirrors with lights, allow increased visibility when backing up at night -Engine noise is relatively quiet compared to older diesel pick ups, can order at fast food drive throughs without shutting engine off -Fuel economy is good for a vehicle of this size (I have 3500HD, not 2500HD) -Driver safety features and various camera views are very helpful -Trim version for this review is Denali, with power running boards, really not missing anything significant
Anonymous
Reviewed a 2021 GMC Sierra 2500HD on Sep 3, 2022
An absolutely beautiful pickup ! Handles & rides exceptionally well !! Nobody will regret making the decision to purchase this awesome truck .
jordyn c
Reviewed a 2021 GMC AT4 Crew Cab 4WD on Dec 4, 2023
This car is not missing nothing at all it is perfect
Kevin K
Reviewed a 2021 GMC Sierra 2500HD on Apr 21, 2022
So far we are very happy.We appreciate the options and layout
2021 GMC Sierra 2500HD Trims
| Trim type | MSRP |
|---|---|
| LB 4WD | $39,000 |
| Double Cab 4WD | $41,600 |
| SLE Double Cab 4WD | $46,400 |
| Base Crew Cab 4WD | $43,400 |
| SLT Crew Cab 4WD | $56,200 |
| SLE Crew Cab 4WD | $48,200 |
| AT4 Crew Cab 4WD | $59,100 |
| Denali Crew Cab 4WD | $65,500 |
2021 GMC Sierra 2500HD Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 GMC Sierra 2500HD prices has changed over time.
See more price trends2021 GMC Sierra 2500HD Pricing Analysis: Los Angeles, CA Market Report
Pricing by Nearby Locations
Market Area: Los Angeles, CA
Key Insights
- Highest Average Price in Lancaster: At $66,911, Lancaster shows the highest average pricing, indicating a strong demand or limited availability in this market.
- Lowest Price in 2014 Models: Temecula, with an average price of $57,889, represents the least expensive market, suggesting more competitive pricing or higher inventory turnover.
- Stable Pricing Across Markets: Markets like Pomona and Santa Clarita, both with 130 listings, show comparable pricing at ~$59,000, indicating a relatively stable pricing environment.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Lancaster, CA | 127 | $66,911 |
| Pomona, CA | 130 | $59,393 |
| Santa Clarita, CA | 130 | $59,283 |
| San Bernardino, CA | 125 | $57,889 |
| Malibu, CA | 127 | $56,740 |
| Irvine, CA | 127 | $56,887 |
| Ventura, CA | 125 | $57,448 |
| Victorville, CA | 127 | $62,400 |
| Temecula, CA | 124 | $57,889 |
Pricing Analysis by Model Year
Key Insights
- Highest Priced New Model: The 2026 GMC Sierra 2500HD, priced at $91,448, indicates exceptionally high demand for the newest model, with a significant markup of ~94.5% over its MSRP.
- Notable Depreciation for Older Models: The 2019 model experiences a substantial drop, priced -14.7% below MSRP, reflecting a steep depreciation trend indicative of the full-size truck market.
- Value Opportunity in Mid-Years: Models from 2020 to 2022 hover around $48,000 to $51,000, representing a potential value sweet spot compared to steep depreciation in older models.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 | $47,000 | $91,448 | +94.5% |
| 2025 | $46,300 | $77,177 | +66.7% |
| 2024 | $45,400 | $75,797 | +66.7% |
| 2023 | $42,200 | $56,688 | +34.3% |
| 2022 | $36,200 | $51,754 | +43.0% |
| 2020 | $35,800 | $48,327 | +35.0% |
| 2019 | $38,200 | $32,626 | -14.7% |
| 2018 | $35,000 | $37,964 | +5.6% |
| 2017 | $34,190 | $39,995 | +16.5% |
| 2016 | $33,535 | $34,748 | +3.6% |
| 2015 | $33,195 | $38,396 | +15.6% |
| 2014 | $31,310 | $25,900 | -17.2% |
These recommendations are based on CarGurus' proprietary market data from June 11, 2026, CarGurus experts' opinions, and generative AI.