2021 Toyota Sienna vs 2021 Nissan Murano
Overview | |
MSRP$34,460 | MSRP$32,810 |
Listings678 | Listings548 |
Ratings & Reviews | |
User Reviews | User Reviews |
Expert reviews8.3 out of 10 | Expert reviews7.8 out of 10 |
Pros
Cons
| Pros
Cons
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2021 Toyota Sienna Reviews SummaryToyota’s minivan got a major makeover for 2021, now entering its fourth generation of production since debuting as a 1997 model. For the first time, the Sienna gets a hybrid gasoline-electric powertrain, and not only that—it’s standard equipment. The Sienna Hybrid is built on the Toyota New Global Architecture (TNGA-K) platform, shared with the Highlander and other current Toyota models. | |
2021 Nissan Murano Reviews SummaryWhile most midsize SUVs offer three rows, the 2021 Nissan Murano focuses on two rows of comfortable seating. Rivals like the Honda Passport have come on the scene in recent years, but Nissan’s comfortable crossover never left. The Murano was introduced in 2002 as a 2003 model, and the third generation arrived for the 2015 model year. Last refreshed for 2019, the Murano carries over into the 2021 model year largely unchanged, although it does get some additional standard safety features. | |
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Popular Features & Specs | |
Engine2.5L 245 hp I4 Hybrid | Engine3.5L 260 hp V6 |
Drive TrainFWD | Drive TrainFWD |
Seating Capacity8 | Seating Capacity5 |
Horsepower | Horsepower260 hp @ 6000 rpm |
EV Battery Capacity1.9 kWh | EV Battery Capacity |
MPG City36 | MPG City20 |
MPG Highway36 | MPG Highway28 |
Engine | |
Engine Name2.5L 245 hp I4 Hybrid | Engine Name3.5L 260 hp V6 |
Torque | Torque240 lb-ft @ 4400 rpm |
Horsepower | Horsepower260 hp @ 6000 rpm |
DrivetrainFWD | DrivetrainFWD |
Fuel Economy | |
EV Battery Capacity1.9 kWh | EV Battery Capacity |
MPG City36 | MPG City20 |
MPG Highway36 | MPG Highway28 |
Interior | |
Seating Capacity8 | Seating Capacity5 |
Safety | |
Front Crash Overall4 | Front Crash Overall5 |
Side Crash Overall5 | Side Crash Overall5 |
Dimensions & Capacity | |
Cargo Space33.5 cu ft | Cargo Space32.1 cu ft |
Curb Weight4610 lbs | Curb Weight3833 lbs |
Height68.5 in | Height67.8 in |
Length203.7 in | Length192.8 in |
Width78.5 in | Width75.4 in |
Wheelbase120.5 in | Wheelbase111.2 in |
Maximum Payload1560 lbs | Maximum Payload1277 lbs |
Number of doors4 | Number of doors4 |
Maximum Towing Capacity3500 lbs | Maximum Towing Capacity |
Overview | ||
MSRP | $34,460 | $32,810 |
Listings | ||
Ratings & Reviews | ||
User reviews | ||
Expert reviews | 8.3 out of 10Read full review | 7.8 out of 10Read full review |
Pros & cons | Pros
Cons
| Pros
Cons
|
Summary | Toyota’s minivan got a major makeover for 2021, now entering its fourth generation of production since debuting as a 1997 model. For the first time, the Sienna gets a hybrid gasoline-electric powertrain, and not only that—it’s standard equipment. The Sienna Hybrid is built on the Toyota New Global Architecture (TNGA-K) platform, shared with the Highlander and other current Toyota models. | While most midsize SUVs offer three rows, the 2021 Nissan Murano focuses on two rows of comfortable seating. Rivals like the Honda Passport have come on the scene in recent years, but Nissan’s comfortable crossover never left. The Murano was introduced in 2002 as a 2003 model, and the third generation arrived for the 2015 model year. Last refreshed for 2019, the Murano carries over into the 2021 model year largely unchanged, although it does get some additional standard safety features. |
Video | No video found | |
Popular Features & Specs | ||
Engine | 2.5L 245 hp I4 Hybrid | 3.5L 260 hp V6 |
Drive Train | FWD | FWD |
Seating Capacity | 8 | 5 |
Horsepower | 260 hp @ 6000 rpm | |
EV Battery Capacity | 1.9 kWh | |
MPG City | 36 | 20 |
MPG Highway | 36 | 28 |
Engine | ||
Engine Name | 2.5L 245 hp I4 Hybrid | 3.5L 260 hp V6 |
Torque | 240 lb-ft @ 4400 rpm | |
Horsepower | 260 hp @ 6000 rpm | |
Drivetrain | FWD | FWD |
Fuel Economy | ||
EV Battery Capacity | 1.9 kWh | |
MPG City | 36 | 20 |
MPG Highway | 36 | 28 |
Interior | ||
Seating Capacity | 8 | 5 |
Safety | ||
Front Crash Overall | 4 | 5 |
Side Crash Overall | 5 | 5 |
Dimensions & Capacity | ||
Cargo Space | 33.5 cu ft | 32.1 cu ft |
Curb Weight | 4610 lbs | 3833 lbs |
Height | 68.5 in | 67.8 in |
Length | 203.7 in | 192.8 in |
Width | 78.5 in | 75.4 in |
Wheelbase | 120.5 in | 111.2 in |
Maximum Payload | 1560 lbs | 1277 lbs |
Number of doors | 4 | 4 |
Maximum Towing Capacity | 3500 lbs | |
The 2021 Toyota Sienna Hybrid aimed to redefine the minivan aesthetic, presenting a more SUV-like appearance. Its wide grille and horizontally arranged LED headlamp arrays gave it a sleek look, while the sculpted sliding side doors and various alloy wheel sizes added to its assertive stance. The rear design managed to look wide and low, maintaining Toyota's high standards of fit and finish. Inside, the Sienna emphasized width with horizontal lines, offering a higher seating position than a sedan and a simple, uncluttered dashboard. The center console was practical, featuring multiple cupholders and a large storage compartment. The second and third rows provided ample comfort and flexibility, with the second row sliding fore and aft for maximum utility.
The 2021 Nissan Murano, once a cutting-edge design, had become more mainstream with its L-shaped LED headlights and contoured front end. Its interior was conservative but functional, with controls intuitively placed for ease of use. The Murano's trims ranged from the base S with 18-inch alloy wheels and an 8-inch touchscreen to the top-tier Platinum, which featured a dual-panel panoramic moonroof and premium leather seats. The Murano focused on comfort, making it an ideal vehicle for commutes and road trips.















The 2021 Toyota Sienna Hybrid was Toyota's first hybrid minivan, featuring a 2.5-liter four-cylinder engine and two electric motors that produced a combined 243 horsepower. It offered front-wheel drive as standard, with all-wheel drive available on all trims. The Sienna used an electronically controlled continuously variable automatic transmission (CVT), which, while efficient, tended to blunt throttle response. The Sienna's handling was significantly improved over previous models, thanks to new front suspension and independent rear trailing arm suspension. Its fuel economy was impressive, with FWD models achieving 36 mpg in all driving conditions and AWD models rated at 35/36/35 mpg combined.
The 2021 Nissan Murano came with a single engine option: a 3.5-liter V6 producing 260 horsepower and 240 pound-feet of torque. This engine was paired with a CVT, offering standard front-wheel drive and optional all-wheel drive. The V6 provided strong low-speed acceleration, though the CVT dulled its power at higher speeds. The Murano excelled in comfort, offering a smooth ride and refined driving characteristics. However, its towing capacity was limited to 1,500 pounds, which was lower than many other midsize SUVs.
The 2021 Toyota Sienna excelled in convenience and functionality, with a standard third-row 60/40-split bench that easily stored away. The second row could slide up to 25 inches, facilitating access to the third row. The cabin featured 16 cupholders and ample storage cubbies. The Sienna could carry a full four-by-eight sheet of plywood with the tailgate closed, offering 33.5 cubic feet of cargo space behind the third row, 75.2 cubic feet behind the second row, and 101.0 cubic feet behind the first row. Its hybrid battery was cleverly tucked under the front seats, preserving cargo space. Both side sliding doors and the rear tailgate were power-operated, responding to kick motions for easy access.
The 2021 Nissan Murano offered up to 67 cubic feet of cargo space with the rear seats folded and 32.1 cubic feet with the seats in use. While other two-row SUVs provided more cargo space, the Murano compensated with ease of use, featuring a center console loaded with trays and cubbies. The Murano's two rows of seating provided ample headroom and legroom, with the second-row seats offering partial reclining functionality. The SL and Platinum trims included a hands-free power liftgate for added convenience.
The 2021 Toyota Sienna was packed with technology, featuring a standard nine-inch touchscreen with Apple CarPlay, Android Auto, and Amazon Alexa. It offered various connectivity options, including a year's trial of Safety Connect and Remote Connect, a ten-year trial of Service Connect, and a three-month trial of AT&T WiFi Connect. Higher trims included a Premium Audio + JBL package with 12 speakers and a rear-seat entertainment system. The driver benefited from a color multi-information display and, in Platinum trims, a 10-inch color Head-Up Display. Remote keyless entry and push-button start were standard, with the Smart Key System available on higher trims.
The 2021 Nissan Murano came standard with an 8-inch touchscreen infotainment system, featuring Apple CarPlay and Android Auto. The system was user-friendly, with hard buttons and dials for easy navigation. Available tech features included an 11-speaker Bose premium stereo system and navigation.
The 2021 Toyota Sienna Hybrid came with Toyota Safety Sense 2.0, which included dynamic radar cruise control, lane-tracing assist, and a pre-collision system with pedestrian and bicyclist detection. It also featured the Star Safety System, 10 airbags, and a rear-seat reminder system. A tire pressure monitoring system and an inflator kit were standard, with an optional spare tire. The 2020 Sienna received high safety ratings, though 2021 ratings were not yet available.
The 2021 Nissan Murano included Nissan Safety Shield 360, featuring reverse automatic emergency braking, blind-spot monitoring, and lane departure warning. Additional standard features included forward automatic emergency braking and driver drowsiness monitoring. Optional features included a surround-view parking monitor and adaptive cruise control.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Toyota Sienna is 8.3 out of 10, while the 2021 Nissan Murano scores 7.8 out of 10. Based on these ratings, the 2021 Toyota Sienna is the recommended choice, offering superior versatility, fuel efficiency, and safety features.
Choose the 2021 Toyota Sienna if:
- You need a versatile and spacious vehicle with excellent cargo capacity.
- You prioritize fuel efficiency and hybrid technology.
- You want a minivan with advanced safety features and high safety ratings.
Choose the 2021 Nissan Murano if:
- You prefer a two-row SUV with ample headroom and legroom.
- You value a user-friendly infotainment system with standard Apple CarPlay and Android Auto.
- You seek a comfortable ride for commutes and road trips.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Toyota Sienna is 8.3 out of 10, while the 2021 Nissan Murano scores 7.8 out of 10. Based on these ratings, the 2021 Toyota Sienna is the recommended choice, offering superior versatility, fuel efficiency, and safety features.
Choose the 2021 Toyota Sienna if:
Shop Now- You need a versatile and spacious vehicle with excellent cargo capacity.
- You prioritize fuel efficiency and hybrid technology.
- You want a minivan with advanced safety features and high safety ratings.
Choose the 2021 Nissan Murano if:
Shop Now- You prefer a two-row SUV with ample headroom and legroom.
- You value a user-friendly infotainment system with standard Apple CarPlay and Android Auto.
- You seek a comfortable ride for commutes and road trips.

By: CarGurus + AI
At CarGurus, our team of experienced automotive writers remain at the heart of our content operation, conducting hands-on car tests and writing insightful guides that are backed by years of industry experience. To complement this, we are harnessing AI to make our content offering more diverse and more helpful to shoppers than ever. To achieve this, our AI systems are based exclusively on CarGurus content, ratings and data, so that what we produce is both unique to CarGurus, and uniquely helpful to car shoppers.







































