2021 Lexus RX vs 2022 Mercedes-Benz GLS

The 2021 Lexus RX showcased a modern design aesthetic that was quintessentially Lexus, featuring a large grille, angular headlamps, and a floating roof. The interior was luxurious, with sumptuous seating and perforated leather upholstery, although the center console design was considered bland and somewhat dated. Lexus offered the RX in five variants, including the performance-focused RX F Sport and the extended-body RXL models with a third row of seating. The exterior boasted standard 18-inch aluminum wheels and LED lighting, with available upgrades like 20-inch wheels and triple-beam LED headlights. Inside, even the base model was well-appointed, with options for semi-aniline leather upholstery and heated seats. However, the infotainment system, while functional, was criticized for its dated appearance and lack of wireless Apple CarPlay or Android Auto.

In contrast, the 2022 Mercedes-Benz GLS presented a more subtle and less flashy look in its base GLS 450 form, avoiding the gaudy grilles of some competitors. The AMG GLS 63 and Maybach versions offered more visual drama with features like flared wheel arches and chrome accents. The interior of the GLS 450 was luxurious, with leather upholstery, a panoramic roof, and ambient lighting, although it lacked some of the more opulent features of higher trims. The digital instrument cluster and infotainment touchscreen were well-integrated, providing a high-quality feel. However, the suspension was noted for poor body control, detracting from the overall comfort. The GLS was equipped with a digital instrument cluster and a user-friendly infotainment system, although it lacked some advanced features found in other Mercedes models.

The 2021 Lexus RX was powered by a 3.5-liter V6 engine, delivering 295 horsepower and 267 pound-feet of torque, paired with an eight-speed automatic transmission. The RX Hybrid models offered 308 horsepower with a combination of a V6 engine and three electric motors, managed by an electronic continuously variable transmission (e-CVT). The RX was known for its comfortable cruising capabilities, with the F Sport model providing a bit more spirited performance. The RX achieved a top speed of 124 mph and accelerated from zero to 60 mph in 7.7 to 7.9 seconds, depending on the drivetrain. Fuel efficiency varied, with the FWD RX 350 rated at 23 mpg combined, while the RX Hybrid models managed up to 31 mpg in the city.

The 2022 Mercedes-Benz GLS 450 featured a 3.0-liter turbocharged inline six-cylinder engine, producing 362 horsepower and 369 pound-feet of torque, with an additional 21 hp and 184 lb-ft of torque available from the EQ Boost mild-hybrid system. The GLS 450's engine was paired with a nine-speed automatic transmission and standard 4Matic all-wheel drive. The GLS 450 provided ample power, with the inline-six offering smooth performance. However, the suspension was criticized for excessive motion, impacting comfort. The GLS 450 had a towing capacity of 7,700 pounds, which was competitive but not class-leading.

The 2021 Lexus RX offered a functional interior with seating for five in the two-row models and up to seven in the three-row RXL versions. Front and second-row seating provided ample space, while the third row was tight. Cargo space was limited, with 18.4 cubic feet behind the second row and 56.3 cubic feet with seats folded in the two-row models. The three-row RXL offered just 7.5 cubic feet behind the third row, expanding to 58.5 cubic feet with seats folded. A power liftgate was standard, with a hands-free option available.

The 2022 Mercedes-Benz GLS came standard with a seven-seat configuration, with an optional six-seat version featuring captain's chairs. The second-row seats could slide to increase legroom, offering the best second-row legroom among full-size luxury SUVs. Cargo space was 17.4 cubic feet with all seats in place, expanding to 84.7 cubic feet with the second and third rows folded. The GLS featured one-touch power-folding seats and a power tailgate, with the air suspension aiding in loading cargo. However, some ergonomic issues were noted, such as the touchscreen being difficult to reach.

The 2021 Lexus RX came equipped with an 8-inch infotainment touchscreen, dual-zone automatic climate control, and a nine-speaker sound system. Upgrades included a 12.3-inch touchscreen, wireless charging, and a 15-speaker Mark Levinson surround-sound system. The infotainment system was functional but criticized for its dated interface and lack of wireless Apple CarPlay or Android Auto. The Remote Touch controller was less refined than competitors' systems, taking up valuable console space.

The 2022 Mercedes-Benz GLS featured the MBUX infotainment system with a 12.3-inch touchscreen and digital instrument cluster. Standard features included Apple CarPlay/Android Auto, navigation, and a 13-speaker Burmester audio system. The voice recognition system was praised for its ease of use, while the touchpad controller was found to be overly sensitive. The GLS lacked the augmented-reality navigation feature of the S-Class, and the navigation system occasionally suggested inefficient routes.

The 2021 Lexus RX received the IIHS Top Safety Pick designation, with Good marks in crashworthiness tests. The NHTSA rated the RX 350, RX 350L, and RX 450h with four out of five stars overall. Standard safety features included a rearview camera, 10 airbags, and Lexus Safety System+ 2.0, which offered a suite of driver-assist technologies. However, the RX lacked the advanced hands-off piloting features found in some competitors.

The 2022 Mercedes-Benz GLS came with standard safety features such as forward collision warning, automatic emergency braking, and blind-spot monitoring. Additional features like adaptive cruise control and lane-keep assist were optional. The GLS included Pre Safe, which prepared the vehicle for a collision by tightening seat belts and closing windows. Crash-test ratings from the IIHS and NHTSA were not available at the time of publication.