2021 Lexus IS vs 2022 Mercedes-Benz E-Class
Overview | |
MSRP$39,050 | MSRP$54,950 |
Listings168 | Listings382 |
Ratings & Reviews | |
User Reviews | User Reviews |
Expert reviews7.3 out of 10 | Expert reviews8.2 out of 10 |
Pros
Cons
| |
2021 Lexus IS Reviews SummaryThe Lexus IS enters its fourth generation of production, embodying lessons learned from the LC and RC. The 2021 IS targets enthusiast drivers and luxury buyers who might be thinking German first, and it seeks to recalibrate expectations of what a compact luxury sports sedan can be. | |
2022 Mercedes-Benz E-Class Reviews SummaryFollowing a substantial refresh for the 2021 model year, the 2022 Mercedes-Benz E-Class lineup sees few changes. The most significant of them is the cancelation of AMG E63 and E63 S variants. Reportedly due to supply chain problems, V8 engines are being dropped from much of the 2022 Mercedes-Benz lineup. That leaves the E-Class with turbocharged four-cylinder and six-cylinder power plants. Additionally, automatic high-beam headlights are standard on all 2022 E-Class models, and a couple of paint colors are new. With the coupe and convertible body styles, rear USB charging ports are now standard equipment. | |
No video found | |
Popular Features & Specs | |
Engine2.0L 241 hp I4 | Engine2.0L 255 hp I4 |
Drive TrainRWD | Drive TrainRWD |
Seating Capacity5 | Seating Capacity5 |
Horsepower241 hp @ 5800 rpm | Horsepower255 hp @ 5800 rpm |
MPG City21 | MPG City23 |
MPG Highway31 | MPG Highway31 |
Engine | |
Engine Name2.0L 241 hp I4 | Engine Name2.0L 255 hp I4 |
Torque258 lb-ft @ 1650 rpm | Torque273 lb-ft @ 1800 rpm |
Horsepower241 hp @ 5800 rpm | Horsepower255 hp @ 5800 rpm |
DrivetrainRWD | DrivetrainRWD |
Fuel Economy | |
MPG City21 | MPG City23 |
MPG Highway31 | MPG Highway31 |
Interior | |
Seating Capacity5 | Seating Capacity5 |
Key Features | |
Navigation System | Navigation SystemStandard |
Sunroof/Moonroof | Sunroof/MoonroofStandard |
Safety | |
Front Crash Overall4 | Front Crash Overall5 |
Side Crash Overall5 | Side Crash Overall5 |
Dimensions & Capacity | |
Cargo Space10.8 cu ft | Cargo Space13.1 cu ft |
Curb Weight3715 lbs | Curb Weight3781 lbs |
Height56.5 in | Height57.8 in |
Length185.4 in | Length194.3 in |
Width72.4 in | Width81.3 in |
Wheelbase110.2 in | Wheelbase115.7 in |
Maximum Payload | Maximum Payload1444 lbs |
Number of doors4 | Number of doors4 |
Overview | ||
MSRP | $39,050 | $54,950 |
Listings | ||
Ratings & Reviews | ||
User reviews | ||
Expert reviews | 7.3 out of 10Read full review | 8.2 out of 10Read full review |
Pros & cons | Pros
Cons
| |
Summary | The Lexus IS enters its fourth generation of production, embodying lessons learned from the LC and RC. The 2021 IS targets enthusiast drivers and luxury buyers who might be thinking German first, and it seeks to recalibrate expectations of what a compact luxury sports sedan can be. | Following a substantial refresh for the 2021 model year, the 2022 Mercedes-Benz E-Class lineup sees few changes. The most significant of them is the cancelation of AMG E63 and E63 S variants. Reportedly due to supply chain problems, V8 engines are being dropped from much of the 2022 Mercedes-Benz lineup. That leaves the E-Class with turbocharged four-cylinder and six-cylinder power plants. Additionally, automatic high-beam headlights are standard on all 2022 E-Class models, and a couple of paint colors are new. With the coupe and convertible body styles, rear USB charging ports are now standard equipment. |
Video | No video found | |
Popular Features & Specs | ||
Engine | 2.0L 241 hp I4 | 2.0L 255 hp I4 |
Drive Train | RWD | RWD |
Seating Capacity | 5 | 5 |
Horsepower | 241 hp @ 5800 rpm | 255 hp @ 5800 rpm |
MPG City | 21 | 23 |
MPG Highway | 31 | 31 |
Engine | ||
Engine Name | 2.0L 241 hp I4 | 2.0L 255 hp I4 |
Torque | 258 lb-ft @ 1650 rpm | 273 lb-ft @ 1800 rpm |
Horsepower | 241 hp @ 5800 rpm | 255 hp @ 5800 rpm |
Drivetrain | RWD | RWD |
Fuel Economy | ||
MPG City | 21 | 23 |
MPG Highway | 31 | 31 |
Interior | ||
Seating Capacity | 5 | 5 |
Key Features | ||
Navigation System | Standard | |
Sunroof/Moonroof | Standard | |
Safety | ||
Front Crash Overall | 4 | 5 |
Side Crash Overall | 5 | 5 |
Dimensions & Capacity | ||
Cargo Space | 10.8 cu ft | 13.1 cu ft |
Curb Weight | 3715 lbs | 3781 lbs |
Height | 56.5 in | 57.8 in |
Length | 185.4 in | 194.3 in |
Width | 72.4 in | 81.3 in |
Wheelbase | 110.2 in | 115.7 in |
Maximum Payload | 1444 lbs | |
Number of doors | 4 | 4 |
The 2021 Lexus IS made a bold statement about its driver with its athletic proportions and great stance. The design captured motion even while standing still, with an elegant distance between the front axle and dashboard. The fast roofline and the kick-up of the window base at the back of the passenger door added to its sporty look. The new spindle grille with diamond mesh and narrow headlights gave the IS an assertive squint. Inside, the dash was tastefully simple, with a retro hi-fi feel to the center stack. The interior matched the exterior with bold, assertive choices and a modern aesthetic, though the analog clock felt outdated.
The 2022 Mercedes-Benz E-Class, particularly the AMG E53 Cabriolet, looked sensational with its matte-finish paint, premium leather, and carbon fiber trim. Modern Mercedes designs had a purity to them, and the AMG styling, larger wheels, convertible top, and matte-blue paint finish made the E53 Cabriolet stand out. Inside, the high-resolution digital displays, glow-in-the-dark air vents, Burmester speaker grilles, and soft leather exuded luxury. The E53 Cabriolet was a car for wealth flaunters, looking and feeling like nothing but luxury.
















The 2021 Lexus IS brought the sport to the luxury sports sedan category, tested and developed at the Toyota Technical Center Shimoyama. The IS 300 RWD had a 2.0-liter turbocharged inline-four engine with 241 horsepower and 258 pound-feet of torque. The IS 300 AWD had a 3.5-liter V6 with 260 hp and 236 lb-ft of torque, while the IS 350 models had the same V6 tuned to 311 hp and 280 lb-ft of torque. RWD models had an eight-speed automatic transmission, and AWD models had a six-speed automatic. The IS had a top speed of 143 mph, with 0-60 mph times ranging from 6.9 seconds for the IS 300 RWD to 5.6 seconds for the IS 350 RWD. Fuel efficiency varied, with the IS 300 RWD rated at 21/31/25 mpg, and the IS 350 AWD at 19/26/22 mpg.
The 2022 Mercedes-AMG E53 Cabriolet had a 3.0-liter turbo-six engine with EQ Boost mild-hybrid technology, generating 429 horsepower and 384 pound-feet of torque. It accelerated from 0-60 mph in 4.4 seconds. The AMG Speedshift nine-speed automatic transmission and AMG Performance 4Matic+ AWD system provided robust performance. The E53 Cabriolet had AMG-tuned air suspension and performance exhaust, with optional 20-inch wheels and summer performance tires. The car's dual personality allowed it to be a quiet cruiser or a firm, ready performer on mountain roads. The E53 Cabriolet was suitable for three-season, top-down driving, with heated features and AWD for winter driving.
The 2021 Lexus IS had a driver-centered focus with a great driver position and comfortable, supportive seats. The F Sport trim's bolstered seat was standard in IS 350 models, with heating and ventilation. The IS used perforated NuLuxe fabric, a synthetic upholstery that looked and felt like leather. Storage space was ample, with an open cubby, twin cupholders, big door pockets, a decent glovebox, and an under-armrest compartment. The second row was comfortable for two but cramped for three, with legroom negotiated with front-seat occupants. Trunk space was adequate at 10.8 cubic feet, with a temporary spare stored beneath the trunk’s load floor.
The 2022 Mercedes-AMG E53 Cabriolet was a true four-passenger convertible, with comfortable seats and an Aircap system to reduce turbulence. Heated seats, a heated steering wheel, rapid-heating front seats, and heated armrests were standard. The Airscarf neck-warming system and sun-reflective leather added to comfort. Ventilated front seats and a triple-layer acoustic soft top helped keep the cabin cool and quiet. The test car had multi-contour front seats with massage and an Air Balance interior fragrance system. With the top raised, the trunk held 9.5 cubic feet of cargo, reduced by half with the top dropped.
The 2021 Lexus IS offered a touchscreen infotainment system with Android Auto and Apple CarPlay. Lexus Enform services included Safety Connect, Service Connect, WiFi, and Remote, with various trial periods. The Navigation Package included Dynamic Navigation and Destination Assist for three years. The Mark Levinson 17-speaker, 1,800-watt premium surround-sound audio system was a recommended option, providing superb audio quality.
The 2022 Mercedes-Benz E-Class featured the MBUX infotainment system with two 12.3-inch screens. The system included Apple CarPlay, Android Auto, WiFi service, and an augmented reality video overlay for navigation. A head-up display and Burmester surround-sound audio system were available. The MBUX system was complex yet user-friendly, with multiple interaction methods and customization options. The digital assistant could be accidentally activated, especially in a convertible with the top down.
The 2021 Lexus IS had not been rated by IIHS or NHTSA but was expected to have good ratings. Standard Lexus Safety System+ 2.5 included a pre-collision system, lane-departure warning, road-sign recognition, adaptive cruise control, and intelligent high beams. Other features included blind-spot monitoring, rear cross-traffic alert, a backup camera, LED lights, and Lexus Enform Safety Connect with a three-year trial.
The 2022 Mercedes-Benz E-Class had standard forward collision warning, automatic emergency braking, blind-spot monitoring, and rear cross-traffic alert. The E-Class Cabriolet featured pop-up rollbars for rollover protection. Pre Safe and Pre Safe Sound were standard, preparing the cabin and protecting ears during a collision. Active Parking Assist, a surround-view camera system, and rain-sensing wipers with Magic Vision Control were also standard. The Driver Assistance Package included adaptive cruise control, lane-centering assistance, front automatic braking, and more. The test car had this package, providing impressive driver aids.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Lexus IS is 7.3 out of 10, while the 2022 Mercedes-Benz E-Class scores 8.2 out of 10. Based on these ratings, the 2022 Mercedes-Benz E-Class is the recommended choice for its superior performance, luxurious interior, and advanced technology.
Choose the 2021 Lexus IS if:
- You prefer a sporty, driver-focused sedan with a great stance and elegant design.
- You value a comfortable, supportive seat with heating and ventilation options.
- You appreciate a high-quality audio system and a variety of connected services.
Choose the 2022 Mercedes-Benz E-Class if:
- You want a luxurious convertible with a powerful engine and advanced mild-hybrid technology.
- You seek a high-end interior with heated features, massage seats, and a fragrance system.
- You prefer a sophisticated infotainment system with multiple interaction methods and customization options.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Lexus IS is 7.3 out of 10, while the 2022 Mercedes-Benz E-Class scores 8.2 out of 10. Based on these ratings, the 2022 Mercedes-Benz E-Class is the recommended choice for its superior performance, luxurious interior, and advanced technology.
Choose the 2021 Lexus IS if:
Shop Now- You prefer a sporty, driver-focused sedan with a great stance and elegant design.
- You value a comfortable, supportive seat with heating and ventilation options.
- You appreciate a high-quality audio system and a variety of connected services.
Choose the 2022 Mercedes-Benz E-Class if:
Shop Now- You want a luxurious convertible with a powerful engine and advanced mild-hybrid technology.
- You seek a high-end interior with heated features, massage seats, and a fragrance system.
- You prefer a sophisticated infotainment system with multiple interaction methods and customization options.

By: CarGurus + AI
At CarGurus, our team of experienced automotive writers remain at the heart of our content operation, conducting hands-on car tests and writing insightful guides that are backed by years of industry experience. To complement this, we are harnessing AI to make our content offering more diverse and more helpful to shoppers than ever. To achieve this, our AI systems are based exclusively on CarGurus content, ratings and data, so that what we produce is both unique to CarGurus, and uniquely helpful to car shoppers.





































