Used 2022 Toyota Sequoia for Sale nearLancaster, CA

Is the 2022 Toyota Sequoia a good car?

Yes — 5/5 from users and 7.33/10 from CarGurus experts. The model scores 8/10 across Performance, Form and function, and Cost effectiveness.

The 2022 Toyota Sequoia is a traditional full-size SUV with a body-on-frame layout, three-row seating, and available rear-wheel drive or four-wheel drive. That setup makes it a fit for you if you want a truck-based SUV with plenty of cargo space, a powerful engine, and a familiar, durable feel rather than a crossover-like driving experience.

The trade-offs are clear: poor fuel economy and outdated technology are the biggest knocks, and the interior styling also feels dated compared with newer rivals. Even so, the Sequoia’s straightforward strengths make it appealing if you value space, capability, and longevity over modern polish.

Good and great deals account for 33.1% of listings, which suggests there are still some worthwhile opportunities if you shop carefully.

Is the 2022 Toyota Sequoia reliable?

Owners rate it 5/5, a strong signal of long-term satisfaction. The Sequoia’s reputation is built around durability and longevity, and the expert review reinforces that with praise for its robust truck-based construction and an engine/transmission combination described as having an excellent reputation for durability and reliability.

You also get a powertrain that’s built around a proven V8, and the review notes that the SUV is made to last and feels tough enough for family use. If you want a used full-size SUV that prioritizes staying power over sophistication, that’s a meaningful advantage.

For used buyers, the main long-term ownership risk is that age-related wear and outdated systems may matter more than mechanical complexity.

What should I look for when buying a used 2022 Toyota Sequoia?

Accident-free inventory is solid at 87.4% — always verify the vehicle history report.

You should still check the history report carefully, because a clean listing percentage does not replace a proper records review. Prioritize a pre-purchase inspection that focuses on wear items, interior condition, and how well the truck-based chassis has been maintained. Because the Sequoia is an older design, condition matters as much as mileage.

Key things to evaluate:

• Trim level: The base SR5 is the starting point, while higher trims add more comfort and convenience. The Limited stands out because it adds navigation and a 12-speaker audio system, and the Nightshade Special Edition is based on the Limited with darkened exterior trim and black-painted wheels.
• Powertrain: You get one engine choice, a 5.7-liter i-Force V8 with 381 horsepower and 401 pound-feet of torque, paired with a six-speed automatic. RWD is standard, 4WD is available, and TRD Pro models come standard with 4WD.
• Safety package: Toyota Safety Sense P is standard and includes pre-collision system with pedestrian detection, adaptive cruise control, lane-departure alert, and automatic high beams. Blind-spot monitor with rear cross-traffic alert is also standard, along with Toyota’s STAR safety system.
• Infotainment: The standard setup uses a 7-inch touchscreen with Apple CarPlay and Android Auto, plus WiFi connectivity and SiriusXM satellite radio. The Limited adds navigation and a 12-speaker audio system, and a premium audio and convenience package adds native navigation, 14 JBL speakers, a subwoofer, and an amplifier.
• Fuel efficiency: The Sequoia returns 13 mpg city/17 mpg highway/15 mpg combined with RWD and 13 mpg city/17 mpg highway/14 mpg combined with 4WD.

Which 2022 Toyota Sequoia trim should I buy?

The 2022 Toyota Sequoia is offered in 6 trim levels: SR5, TRD Sport, TRD Pro, Limited, Platinum, and Nightshade Special Edition.

Here's the short version:

• SR5: This is the entry point if you want the Sequoia’s core strengths at the lowest price. It gives you the standard V8, standard safety tech, and the basic full-size SUV formula without extra luxury content.
• TRD Sport: Choose this if you want a more distinctive appearance and a sportier flavor while staying within the standard Sequoia structure.
• TRD Pro: This is the one to choose if you want the most off-road-oriented version, since it comes standard with 4WD and gets special suspension attention.
• Limited: This is the best-value trim for many shoppers because it adds navigation and a 12-speaker audio system, and the Nightshade Special Edition is based on it.
• Nightshade Special Edition: Pick this if you want the Limited’s equipment with a darker exterior look, including blacked-out trim and wheels.
• Platinum: This is the top-end comfort choice in the lineup, aimed at buyers who want the most upscale Sequoia experience.

Toyota Safety Sense P and blind-spot monitoring are standard across the lineup.

Is now a good time to buy a used 2022 Toyota Sequoia?

This looks like a moderate, selective buyer’s market, so you should shop with some patience and compare listings carefully.

• Deal availability: 33.1% of listings are priced as good or great deals.
• Inventory: There are 390 listings available.
• Clean inventory: 87.4% of listings are accident-free.

Is the 2022 Toyota Sequoia safe?

Toyota Safety Sense P is standard, and it includes pre-collision system with pedestrian detection, adaptive cruise control, lane-departure alert, and automatic high beams. Blind-spot monitor with rear cross-traffic alert is also standard, along with Toyota’s STAR safety system, which adds stability control, traction control, anti-lock brakes, electronic brake-force distribution, brake assist, and smart-stop technology.

It earns a 7/10 safety score from our experts.

The Sequoia also comes with a full complement of airbags, LATCH connectors in the second row and third-row center position, front energy-absorbing crumple zones, side-impact door beams, trailer sway-control, parking-assist sonar, child-protector rear door locks, and power window lockouts. No crash-test ratings are cited here, so you should lean on the standard safety equipment and the vehicle’s overall size when evaluating it.

Should I buy a 2022 Toyota Sequoia or consider a different year?

If you're weighing the 2022 against nearby model years, here's how to think about it:

Choose the 2022 if:

• 33.1% of listings are priced as good or great deals.
• Accident-free inventory is solid at 87.4% — always verify the vehicle history report.
• Owners rate it 5/5 — a strong satisfaction signal.
• It keeps the traditional body-on-frame, V8-powered full-size SUV formula with standard advanced safety features.

Consider the 2021 if:

• It offers serious space and standard V8 power in a familiar, practical package.

Consider the 2023 if:

• It brings a redesigned, more modernized full-size SUV with a standard hybrid powertrain.

The bottom line: If you want the old-school Sequoia formula, the 2022 is the year to target because it balances proven capability, standard safety tech, and a relatively manageable used-market supply. If you’re more price-sensitive and can live with older tech, the 2021 is the value-oriented alternative; if you want a major redesign and newer technology, the 2023 is the better path.

These recommendations are based on CarGurus' proprietary market data from September 4, 2026, CarGurus experts' opinions, and generative AI.