Used 2022 Mercedes-Benz S-Class for Sale nearIrvine, CA
249 vehicles found
See the total price upfront.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Manufaktur Diamond White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 54,876
- Stock #:
- 26305
- VIN:
- W1K6G6DB8NA166553
Sponsored by Major Motor Cars
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
54,876 mi
$48,897
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- designo Diamond White Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Exclusive Carmine Red/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 48,299
- Stock #:
- MA023377
- VIN:
- W1K6G7GB1MA023377
Sponsored Listing
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
48,299 mi
$59,377
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- MANUFAKTUR Diamond White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 31,861
- Stock #:
- L10936
- VIN:
- W1K6G6DB8PA176261
Sponsored Listing
2023 Mercedes-Benz S-Class
S 500 4MATIC AWD
31,861 mi
$64,084
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3L I6 Hybrid
- Exterior color:
- Obsidian Black Metallic
- Combined gas mileage:
- 49 MPG
- Fuel type:
- Hybrid
- Interior color:
- Sienna Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 30,935
- Stock #:
- PL00480
- VIN:
- W1K6G6KB9PA198210
2023 Mercedes-Benz S-Class
S 580e 4MATIC AWD
30,935 mi
$74,472
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Carmine Red/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 43,861
- Stock #:
- 8995B
- VIN:
- W1K6G7GB3MA043792
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
43,861 mi
$61,973
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 54,238
- Stock #:
- 70031190
- VIN:
- W1K6G7GB8NA150225
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
54,238 mi
$63,497
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- MANUFAKTUR Diamond White Metallic
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Magma Grey)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 67,510
- Stock #:
- B26162
- VIN:
- W1K6G7GB2PA176676
2023 Mercedes-Benz S-Class
S 580 4MATIC AWD
67,510 mi
$60,075
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Gray (Selenite Grey)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 33,780
- Stock #:
- PA182058
- VIN:
- W1K6G6DB8PA182058
2023 Mercedes-Benz S-Class
S 500 4MATIC AWD
33,780 mi
$63,325
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 30,361
- Stock #:
- 226460
- VIN:
- W1K6G6DB6NA125497
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
30,361 mi
$53,973
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Nautical Blue Metallic
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray (Macchiato/Magma Grey)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 25,367
- Stock #:
- PL00630
- VIN:
- W1K6G6DB1NA165504
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
25,367 mi
$61,766
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 16,713
- Stock #:
- A176983
- VIN:
- W1K6G6DB2PA176983
2023 Mercedes-Benz S-Class
S 500 4MATIC AWD
16,713 mi
$65,258
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 43,074
- Stock #:
- PA235449
- VIN:
- W1K6G7GB2PA235449
2023 Mercedes-Benz S-Class
S 580 4MATIC AWD
43,074 mi
$68,950
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- designo Diamond White Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 30,750
- VIN:
- W1K6G7GB2MA035182
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
30,750 mi
$65,084
CarGurus Analysis:
2022 Mercedes-Benz S-Class
With 1,150 currently listed for sale and an average price of $64,062.00, 31.2% of 2022 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
88.9% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class features a luxurious interior with high-quality materials, advanced technology including a 12.8-inch OLED touchscreen, and a powerful 48-volt mild hybrid powertrain.
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Magma Gray)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 25,442
- Stock #:
- A191118P
- VIN:
- W1K6G7GBXPA191118
2023 Mercedes-Benz S-Class
S 580 4MATIC AWD
25,442 mi
$77,532
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 62,171
- Stock #:
- PL00492
- VIN:
- W1K6G7GB0PA192102
2023 Mercedes-Benz S-Class
S 580 4MATIC AWD
62,171 mi
$59,762
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Nautical Blue
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Macchiato/Magma Gray
- Transmission:
- 9-Speed Automatic
- Mileage:
- 38,578
- Stock #:
- A194697P
- VIN:
- W1K6G6DB3PA194697
2023 Mercedes-Benz S-Class
S 500 4MATIC AWD
38,578 mi
$64,533
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Obsidian Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Sienna Brown/Black
- Transmission:
- Automatic
- Mileage:
- 39,377
- Stock #:
- 073511
- VIN:
- W1K6G7GB7NA073511
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
39,377 mi
$65,772
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Manufaktur Kalahari Gold Magno
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 59,916
- Stock #:
- PA169273
- VIN:
- W1K6G7GB0PA169273
2023 Mercedes-Benz S-Class
S 580 4MATIC AWD
59,916 mi
$62,995
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Exclusive Carmine Red/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 63,212
- Stock #:
- 26308
- VIN:
- W1K6G6DB7NA105484
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
63,212 mi
$48,550
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- MANUFAKTUR Diamond White
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray (Macchiato/Magma Grey)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 31,936
- Stock #:
- CGSP16604
- VIN:
- W1K6G7GB3NA166672
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
31,936 mi
$65,080
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Emerald Green Metallic
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Macchiato/Magma Gray
- Transmission:
- 9-Speed Automatic
- Mileage:
- 43,184
- Stock #:
- 4P2384
- VIN:
- W1K6G6DB1PA189739
2023 Mercedes-Benz S-Class
S 500 4MATIC AWD
43,184 mi
$52,369
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Gray
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (TAN)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 31,875
- Stock #:
- A3772
- VIN:
- W1K6G7GB0NA112214
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
31,875 mi
$67,914
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 30,361
- Stock #:
- 226460
- VIN:
- W1K6G6DB6NA125497
Sponsored Listing
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
30,361 mi
$53,973
CarGurus Analysis: 2022 Mercedes-Benz S-Class
overall
Summary
With 1,150 currently listed for sale and an average price of $64,062.00, 31.2% of 2022 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
88.9% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class features a luxurious interior with high-quality materials, advanced technology including a 12.8-inch OLED touchscreen, and a powerful 48-volt mild hybrid powertrain.
Why it stands out
The 2022 Mercedes-Benz S-Class is a benchmark in the luxury sedan segment, combining elegance, performance, and cutting-edge technology. With its sleek design and spacious interior, it offers a comfortable ride for both drivers and passengers. The S-Class is equipped with a 48-volt mild hybrid system, enhancing performance while maintaining fuel efficiency, with the S500 achieving up to 21 mpg city and 30 mpg highway. The interior is adorned with premium materials and features like a 12.8-inch OLED touchscreen and a 12.3-inch digital instrument panel, providing a modern and intuitive user experience. Safety is paramount, with advanced driver assistance systems and high safety ratings, making it a top choice for those seeking both luxury and peace of mind. While the price tag may be high, the overall excellence and prestige of the S-Class make it a worthy investment for luxury car buyers.
Other model years to consider
- Average price: $78,756.00
- Good/great deal percentage: 30.6%
- User rating: Not available
- Total listings: 1,240
- Average price: $25,682.00
- Good/great deal percentage: 31.0%
- User rating: 4.95 / 5
- Total listings: 945
- Average price: $22,569.00
- Good/great deal percentage: 30.8%
- User rating: 5 / 5
- Total listings: 775
This analysis is based on CarGurus' proprietary market data from July 6, 2026, CarGurus experts' opinions, and generative AI.
4.5 Overall rating
Filter by rating
Nabeel J
Reviewed a 2022 Mercedes-Benz S-Class on Apr 25, 2022
The S Class provides safety and comfort for its riders. At first, I decided to purchase the BMW 745e after comparing it with the Audi A8. I decided to give the Mercedes S class a try. After the test drive, I immediately decided to purchase the Mercedes S580. I do not regret my purchase at all. All of the looks of the car look fabulous. The ambient lighting is breathtaking as well as the display screen. The panoramic sunroof is also one of my favorites. I live in a hilly area, but I can’t even tell when going up the hill since the S580 is a powerful vehicle.
Sajid S
Reviewed a 2022 Mercedes-Benz S-Class on Dec 27, 2021
It’s been a pinnacle of luxury, however nothing stands out compared to previous models except some businesses including indoor lighting etc. the screen seems odd ;stands out in the middle and does not merge with the rest of the dashboard
Anonymous
Reviewed a 2022 Mercedes-Benz S-Class on Jun 7, 2024
The only option I wish it had was the premier stereo system. Otherwise the car was perfect. It was basically a new vehicle. The price I actually paid was great based on the immaculate condition and very low mileage.
Joyce E
Reviewed a 2022 Mercedes-Benz S-Class on Apr 18, 2024
This car has a manufacturer recall on its fuel pump mechanism, and it is a hybrid car, so for someone who leaves the car parked in the garage for 2 straight weeks, it may cause the battery to die and may not be suited for my needs/lifestyle
2022 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| S 580 4MATIC AWD | $117,700 |
| S 500 4MATIC AWD | $111,100 |
| Maybach S 680 4MATIC AWD | $229,000 |
| Maybach S 580 4MATIC AWD | $184,900 |
2022 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz S-Class prices has changed over time.
See more price trendsFAQs
How much does the 2022 Mercedes-Benz S-Class cost in Irvine, CA?
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