Used 2022 Mercedes-Benz S-Class for Sale near Cleveland, OH
233 results
CarGurus Analysis:
2022 Mercedes-Benz S-Class
With 221 currently listed for sale near Cleveland, OH and an average price of $78,628.00, 29.0% of 2022 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.8 / 5 stars.
89.1% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class boasts a sleek design, powerful performance with a mild-hybrid powertrain, and luxurious interior features.
CarGurus Analysis: 2022 Mercedes-Benz S-Class
overall

Summary
With 221 currently listed for sale near Cleveland, OH and an average price of $78,628.00, 29.0% of 2022 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.8 / 5 stars.
89.1% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class boasts a sleek design, powerful performance with a mild-hybrid powertrain, and luxurious interior features.
Why it stands out
The 2022 Mercedes-Benz S-Class continues to be the benchmark in the full-size luxury sedan market, characterized by its sophisticated design and exceptional performance attributes. It features a choice between a turbocharged 3.0-liter inline-six (S500) and a twin-turbo 4.0-liter V8 (S580) powertrain, both complemented by a 48-volt mild hybrid system known as EQ Boost, enhancing efficiency and providing a seamless power boost when needed. The infamous S-Class comfort extends to both front and rear passengers with high-quality materials, advanced technology, and cutting-edge driver assistance features, ensuring a serene driving experience.
Highlighted by a 12.8-inch OLED touchscreen and a customizable 12.3-inch digital instrument panel, the technology in the S-Class not only provides functionality but also enhances the overall luxury feel. Despite potential concerns over its polarizing design and high price, the S-Class remains an appealing choice for buyers seeking the ultimate in executive transportation, blending modern tech, efficiency, and driving pleasure.
Other model years to consider
- Average price: $22,397.00
- Good/great deal percentage: 28.2%
- User rating: 4.88 / 5
- Total listings: 209
- Average price: $22,621.00
- Good/great deal percentage: 26.8%
- User rating: 4.89 / 5
- Total listings: 164
- Average price: $83,661.00
- Good/great deal percentage: 32.9%
- User rating: 5 / 5
- Total listings: 167
This analysis is based on CarGurus' proprietary market data from April 7, 2026, CarGurus experts' opinions, and generative AI.
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Anonymous
Reviewed a 2022 Mercedes-Benz S-Class on Jun 7, 2024
The only option I wish it had was the premier stereo system. Otherwise the car was perfect. It was basically a new vehicle. The price I actually paid was great based on the immaculate condition and very low mileage.
Joyce E
Reviewed a 2022 Mercedes-Benz S-Class on Apr 18, 2024
This car has a manufacturer recall on its fuel pump mechanism, and it is a hybrid car, so for someone who leaves the car parked in the garage for 2 straight weeks, it may cause the battery to die and may not be suited for my needs/lifestyle
Nabeel J
Reviewed a 2022 Mercedes-Benz S-Class on Apr 25, 2022
The S Class provides safety and comfort for its riders. At first, I decided to purchase the BMW 745e after comparing it with the Audi A8. I decided to give the Mercedes S class a try. After the test drive, I immediately decided to purchase the Mercedes S580. I do not regret my purchase at all. All of the looks of the car look fabulous. The ambient lighting is breathtaking as well as the display screen. The panoramic sunroof is also one of my favorites. I live in a hilly area, but I can’t even tell when going up the hill since the S580 is a powerful vehicle.
Sajid S
Reviewed a 2022 Mercedes-Benz S-Class on Dec 27, 2021
It’s been a pinnacle of luxury, however nothing stands out compared to previous models except some businesses including indoor lighting etc. the screen seems odd ;stands out in the middle and does not merge with the rest of the dashboard
2022 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| S 580 4MATIC AWD | $117,700 |
| S 500 4MATIC AWD | $111,100 |
| Maybach S 680 4MATIC AWD | $229,000 |
| Maybach S 580 4MATIC AWD | $184,900 |
2022 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz S-Class prices has changed over time.
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