Used 2022 Mercedes-Benz S-Class for Sale near Ohio
245 results
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Obsidian Black Metallic
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black Exclusive Nappa Leather
- Transmission:
- Automatic
- Mileage:
- 32,598
- Stock #:
- 938211
- VIN:
- W1K6G6DBXPA181641
2023 Mercedes-Benz S-Class
S 500 4MATIC AWD
32,598 mi
$68,900
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 40,905
- Stock #:
- 28750506
- VIN:
- W1K6G7GB4PA232665
2023 Mercedes-Benz S-Class
S 580 4MATIC AWD
40,905 mi
$72,997
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Gray (Graphite Grey Metallic)
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 37,277
- Stock #:
- 9254-TR
- VIN:
- W1K6G7GB9MA043957
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
37,277 mi
$65,861
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Gray
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 48,097
- Stock #:
- 056771
- VIN:
- W1K6G7GB5MA056771
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
48,097 mi
$56,094
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Obsidian Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Sienna Brown/Black
- Transmission:
- Automatic
- Mileage:
- 39,377
- Stock #:
- 073511
- VIN:
- W1K6G7GB7NA073511
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
39,377 mi
$68,603
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- MANUFAKTUR Kalahari Gold Magno
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Silver Gray/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 37,086
- Stock #:
- 236808
- VIN:
- W1K6G7GB9PA236808
2023 Mercedes-Benz S-Class
S 580 4MATIC AWD
37,086 mi
$75,761
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Red
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 19,741
- Stock #:
- 017428
- VIN:
- W1K6G7GB6MA017428
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
19,741 mi
$63,551
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Manufaktur Diamond White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 54,876
- Stock #:
- 26305
- VIN:
- W1K6G6DB8NA166553
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
54,876 mi
$50,801
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Gray
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 30,228
- Stock #:
- STK161052
- VIN:
- W1K6G7GB3NA161052
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
30,228 mi
$62,097
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (TAN)
- Transmission:
- Automatic
- Mileage:
- 51,505
- Stock #:
- 70019067
- VIN:
- W1K6G7GB7MA035825
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
51,505 mi
$59,397
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Red (Burgundy)
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (TAN)
- Transmission:
- Automatic
- Mileage:
- 15,918
- Stock #:
- 70046696
- VIN:
- W1K6G6DB2NA069106
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
15,918 mi
$64,347
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- designo Diamond White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 17,509
- Stock #:
- 26463A
- VIN:
- W1K6G6DB6MA031716
2021 Mercedes-Benz S-Class
S 500 Sedan 4MATIC
17,509 mi
$54,602
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- MANUFAKTUR Cashmere White Magno
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Exclusive Carmine Red/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 39,500
- Stock #:
- 30205
- VIN:
- W1K6G7GB8NA112851
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
39,500 mi
$70,446
CarGurus Analysis:
2022 Mercedes-Benz S-Class
With 1,149 currently listed for sale and an average price of $65,142.00, 32.6% of 2022 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
88.3% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class features a turbocharged 3.0-liter inline-six engine or a twin-turbo 4.0-liter V8, both powered by a 48-volt mild hybrid system, providing an elevated performance experience.
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Manufaktur Diamond White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 39,694
- Stock #:
- 26136
- VIN:
- W1K6G6DB5NA164436
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
39,694 mi
$57,140
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 35,245
- Stock #:
- 938021
- VIN:
- W1K6G6DB2PA186848
2023 Mercedes-Benz S-Class
S 500 4MATIC AWD
35,245 mi
$68,900
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- MANUFAKTUR Diam
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 25,965
- Stock #:
- 152088MM
- VIN:
- W1K6G7GB1NA152088
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
25,965 mi
$71,642
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 33,000
- Stock #:
- 28885419
- VIN:
- W1K6G7GB8NA155795
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
33,000 mi
$70,247
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Gray
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 38,597
- Stock #:
- 70051188
- VIN:
- W1K6G7GBXMA048875
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
38,597 mi
$63,197
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 44,289
- Stock #:
- 70020949
- VIN:
- W1K6G7GBXNA071364
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
44,289 mi
$66,597
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 24,832
- Stock #:
- 189196
- VIN:
- W1K6G6DB0PA189196
2023 Mercedes-Benz S-Class
S 500 4MATIC AWD
24,832 mi
$67,958
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 33,173
- Stock #:
- 44037
- VIN:
- W1K6G6DB9NA163712
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
33,173 mi
$58,287
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 16,713
- Stock #:
- A176983
- VIN:
- W1K6G6DB2PA176983
2023 Mercedes-Benz S-Class
S 500 4MATIC AWD
16,713 mi
$72,226
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Coupe
- Doors:
- 2 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Obsidian Black Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- designo Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 57,268
- Stock #:
- 051415
- VIN:
- W1KXJ8JB7MA051415
2021 Mercedes-Benz S-Class
AMG S 63 Coupe 4MATIC
57,268 mi
$87,138
CarGurus Analysis: 2022 Mercedes-Benz S-Class
overall
Summary
With 1,149 currently listed for sale and an average price of $65,142.00, 32.6% of 2022 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
88.3% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class features a turbocharged 3.0-liter inline-six engine or a twin-turbo 4.0-liter V8, both powered by a 48-volt mild hybrid system, providing an elevated performance experience.
Why it stands out
The 2022 Mercedes-Benz S-Class continues its legacy as a premier luxury sedan, showcasing a perfect fusion of performance, elegance, and advanced technology. Notably, the introduction of a 48-volt mild hybrid powertrain enhances fuel efficiency while delivering impressive power outputs—up to 429 horsepower in the S500 and even higher in the S580 variant. Beyond performance, the interior exudes luxury with high-quality materials, an elegant design, and a plethora of technology features such as the immersive 12.8-inch OLED touchscreen and advanced driver assistance systems. With outstanding ratings for both safety and comfort, the S-Class provides a unique blend that appeals to discerning buyers seeking the best in executive transportation.
Other model years to consider
- Average price: $79,591.00
- Good/great deal percentage: 32.4%
- User rating: Not available
- Total listings: 1,250
- Average price: $25,984.00
- Good/great deal percentage: 34.3%
- User rating: 4.95 / 5
- Total listings: 944
- Average price: $22,399.00
- Good/great deal percentage: 33.5%
- User rating: 5 / 5
- Total listings: 786
This analysis is based on CarGurus' proprietary market data from June 15, 2026, CarGurus experts' opinions, and generative AI.
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4.5 Overall rating
Filter by rating
Nabeel J
Reviewed a 2022 Mercedes-Benz S-Class on Apr 25, 2022
The S Class provides safety and comfort for its riders. At first, I decided to purchase the BMW 745e after comparing it with the Audi A8. I decided to give the Mercedes S class a try. After the test drive, I immediately decided to purchase the Mercedes S580. I do not regret my purchase at all. All of the looks of the car look fabulous. The ambient lighting is breathtaking as well as the display screen. The panoramic sunroof is also one of my favorites. I live in a hilly area, but I can’t even tell when going up the hill since the S580 is a powerful vehicle.
Sajid S
Reviewed a 2022 Mercedes-Benz S-Class on Dec 27, 2021
It’s been a pinnacle of luxury, however nothing stands out compared to previous models except some businesses including indoor lighting etc. the screen seems odd ;stands out in the middle and does not merge with the rest of the dashboard
Anonymous
Reviewed a 2022 Mercedes-Benz S-Class on Jun 7, 2024
The only option I wish it had was the premier stereo system. Otherwise the car was perfect. It was basically a new vehicle. The price I actually paid was great based on the immaculate condition and very low mileage.
Joyce E
Reviewed a 2022 Mercedes-Benz S-Class on Apr 18, 2024
This car has a manufacturer recall on its fuel pump mechanism, and it is a hybrid car, so for someone who leaves the car parked in the garage for 2 straight weeks, it may cause the battery to die and may not be suited for my needs/lifestyle
2022 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| S 580 4MATIC AWD | $117,700 |
| S 500 4MATIC AWD | $111,100 |
| Maybach S 680 4MATIC AWD | $229,000 |
| Maybach S 580 4MATIC AWD | $184,900 |
2022 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz S-Class prices has changed over time.
See more price trends
