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Used 2021 Mercedes-Benz S-Class for Sale near Ohio

179 results
Cincinnati, OH
2022 Mercedes-Benz S-Class S 580 4MATIC AWD

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

59,615 miles

$63,584

Fair Deal
Certified Pre-Owned
West Chester, OH
17 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Black
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
9-Speed Automatic
Mileage:
59,615
Stock number:
TNA088178
VIN:
W1K6G7GBXNA088178

Sponsored

2022 Mercedes-Benz S-Class S 580 4MATIC AWD

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

18,773 miles

$76,977

Fair Deal
Certified Pre-Owned
Cincinnati, OH
12 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Emerald Green Metallic
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Brown (Macchiato Beige/Magma Gray)
Transmission:
9-Speed Automatic
Mileage:
18,773
Stock number:
ANA139187
VIN:
W1K6G7GB4NA139187

Sponsored

2021 Mercedes-Benz S-Class S 580 Sedan 4MATIC

2021 Mercedes-Benz S-Class

S 580 Sedan 4MATIC

46,741 miles

$55,786

Good Deal
Fort Wright, KY
3 mi away
Year:
2021
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
designo Diamond White
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
9-Speed Automatic Overdrive
Mileage:
46,741
Stock number:
MA024709
VIN:
W1K6G7GB5MA024709

2022 Mercedes-Benz S-Class S 580 4MATIC AWD

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

55,972 miles

$62,997

Good Deal
Store transfer to Florence, KY
1,873 mi away • Price includes $1,999 shipping Price includes $1,999 shipping
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Gray
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
55,972
Stock number:
28424989
VIN:
W1K6G7GB7NA163161

Preparing for a close up...

Photos coming soon

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

59,615 miles

$63,584

Fair Deal
Certified Pre-Owned
West Chester, OH
17 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Black
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
9-Speed Automatic
Mileage:
59,615
Stock number:
TNA088178
VIN:
W1K6G7GBXNA088178

Preparing for a close up...

Photos coming soon

2021 Mercedes-Benz S-Class

S 580 Sedan 4MATIC

54,219 miles

$58,997

Good Deal
Store transfer to Florence, KY
1,883 mi away • Price includes $1,999 shipping Price includes $1,999 shipping
Year:
2021
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Black
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
Automatic
Mileage:
54,219
Stock number:
28397559
VIN:
W1K6G7GBXMA036774

Preparing for a close up...

Photos coming soon

2020 Mercedes-Benz S-Class

S 560 Sedan RWD

46,698 miles

$46,397

Fair Deal
Store transfer to Florence, KY
882 mi away • Price includes $1,399 shipping Price includes $1,399 shipping
Year:
2020
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
463 hp 4L V8
Exterior color:
Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Brown
Transmission:
Automatic
Mileage:
46,698
Stock number:
27294134
VIN:
WDDUG8DB9LA502551

  1. Home
  2. / Used Cars
  3. / Mercedes-Benz S-Class
  4. / 2021
  5. / Ohio
Overview
Reviews
FAQs

CarGurus Analysis: 2021 Mercedes-Benz S-Class

Picture of 2021 Mercedes-Benz S-Class ## Summary - With 808 currently listed for sale on CarGurus and an **average price of $61,370.00**, 31.9% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars. - **83.4% of 2021 S-Class models on CarGurus are accident free**. - The 2021 Mercedes-Benz S-Class was redesigned to maintain its status as a technological showcase, featuring sophisticated infotainment systems and new powertrains. ## Why it stands out The 2021 Mercedes-Benz S-Class stands out in the luxury sedan segment with its remarkable blend of performance, advanced technology, and unrivaled comfort. This model year features a redesign that introduces more sophisticated infotainment options and improved powertrains, such as the 3.0-liter turbocharged inline-six in the S500 and the powerful 4.0-liter twin-turbo V8 in the S580. Notable updates include a drag coefficient (Cd) of 0.22, enhancing aerodynamics, and innovative features like rear-wheel steering, which improves maneuverability. While the car is not primarily a driver’s car, it balances comfortable riding dynamics with precise steering, making it appeal to buyers looking for both luxury and style. However, some users have mentioned issues with run-flat tires. ## Other model years to consider - **[2022 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2022-Mercedes-Benz-S-Class-c31858)** - Average price: $66,621.00 - Good/great deal percentage: 30.6% - User rating: 4.8 / 5 - Total listings: 1,042 - **[2015 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2015-Mercedes-Benz-S-Class-c24430)** - Average price: $25,902.00 - Good/great deal percentage: 29.3% - User rating: 4.88 / 5 - Total listings: 894 - **[2018 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2018-Mercedes-Benz-S-Class-c27088)** - Average price: $35,246.00 - Good/great deal percentage: 34.0% - User rating: 4.76 / 5 - Total listings: 785 This analysis is based on CarGurus' proprietary market data from February 10, 2026, CarGurus experts' opinions, and generative AI.

5 Overall rating

(7 reviews)
Chris V
5.0
Reviewed a 2021 Mercedes-Benz S-Class on Jun 05, 2024

This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.

Deno P
5.0
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023

This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.

Rob G
5.0
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022

Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.

James B
5.0
Reviewed a 2021 Mercedes-Benz S 580 Sedan 4MATIC on Oct 14, 2024

The car is loaded with luxuries , very stylish at the same time sporty. You get a lot of car for the money and they hold there value. BMW would be close cusin to Mercedes.

Bob D
5.0
Reviewed a 2021 Mercedes-Benz S-Class on Mar 15, 2024

Gently used, beautifully maintained, a real classic. Price was a little too much, otherwise I would have signed the deal.

2021 Mercedes-Benz S-Class FAQs

How much does the 2021 Mercedes-Benz S-Class cost in Ohio?

The average 2021 Mercedes-Benz S-Class costs about $61,400.97. The average price has decreased by -8.6% since last year. The 179 for sale near Ohio on CarGurus, range from $27,072 to $151,385 in price.

Is the 2021 Mercedes-Benz S-Class a good car?

CarGurus experts gave the 2021 Mercedes-Benz S-Class an overall rating of 7.5/10 and 2021 Mercedes-Benz S-Class owners have rated the vehicle a 5/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2021 Mercedes-Benz S-Class vehicles in Ohio have no reported accidents or damage?

146 out of 179 for sale near Ohio have no reported accidents or damage.

Is the 2021 Mercedes-Benz S-Class safe?

CarGurus experts gave the 2021 Mercedes-Benz S-Class a safety rating of 7/10.

What is the fuel economy of the 2021 Mercedes-Benz S-Class?

Depending on the engine and options, the 2021 Mercedes-Benz S-Class gets between 16 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

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