Used 2021 RAM 2500 for Sale near Chicago, IL
424 results
CarGurus Analysis:
2021 RAM 2500
With 420 currently listed for sale near Chicago, IL and an average price of $38,375.00, 18.1% of 2021 RAM 2500s for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 RAM 2500 4.48 / 5 stars.
77.6% of 2021 RAM 2500 models on CarGurus are accident free.
The 2021 RAM 2500 is appreciated for its impressive power and fuel efficiency, particularly with the diesel engine, while also offering robust safety features.
CarGurus Analysis: 2021 RAM 2500

Summary
With 420 currently listed for sale near Chicago, IL and an average price of $38,375.00, 18.1% of 2021 RAM 2500s for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 RAM 2500 4.48 / 5 stars.
77.6% of 2021 RAM 2500 models on CarGurus are accident free.
The 2021 RAM 2500 is appreciated for its impressive power and fuel efficiency, particularly with the diesel engine, while also offering robust safety features.
Why it stands out
The 2021 RAM 2500 continues the legacy of its predecessors by blending impressive heavy-duty capabilities with premium features. This truck is not only adept at handling tough workloads but has also elevated its appeal to families by incorporating modern technology and comfort into its design. The improved interiors boast plush amenities and numerous USB ports, creating an inviting atmosphere. Moreover, the powerful turbo-diesel engine option sets the RAM 2500 apart from competitors, providing remarkable towing capacity and efficiency, which are sought after by both work-oriented buyers and recreational users alike. Despite some owner wishes for updated interior tech, such as larger screens, the overall reliability and value of the 2021 RAM 2500 make it a strong contender in the heavy-duty truck market.
Other model years to consider
- Average price: $36,823.00
- Good/great deal percentage: 16.1%
- User rating: 4.74 / 5
- Total listings: 322
- Average price: $42,539.00
- Good/great deal percentage: 20.5%
- User rating: 4.68 / 5
- Total listings: 430
- Average price: $48,561.00
- Good/great deal percentage: 32.8%
- User rating: 4.6 / 5
- Total listings: 615
This analysis is based on CarGurus' proprietary market data from April 7, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles

The Best Pickup Trucks of 2026, Ranked
Pickup truck competition is fierce and change is in the air. Electric trucks and compact pickups are hitting the market, providing new choices for both small businesses and weekend adventurers. But which truck suits your needs best?

2027 Ram 2500 Pricing, Specs, and Release Date
Ram is offering its 2500 Heavy Duty full-size pickup truck in off-road Power Wagon guise for the 2027 model year, and available upgrades make the truck more capable than ever.

Truck Cab Sizes: A Complete Breakdown and Comparison
Confused by all the different truck cab sizes and names? Our guide breaks it down for you, explaining what the various truck cab sizes are and the pros and cons of each.
4.5 Overall rating
Filter by rating
Richard R
Reviewed a 2021 RAM 2500 on Jul 25, 2024
Good solid truck! Ride is good for a 2500. Has a lot of features ,more than needed for a truck , and towing is satisfactory for a gas powered vehicle.
Anonymous
Reviewed a 2021 RAM 2500 on Jul 10, 2021
incredible. especially the artificial intelligence features. Updates such as bullet proof glass an added plus. great power and torque from the cummins. easily pushes other cars out of the way. very good to protect against attempted car jackers with the auto extracting prods We love this truck and applaud the RAM people for meeting consumer needs and wants in 2021. Great value. Very safe. Would buy again.
William S
Reviewed a 2021 RAM 2500 on Jan 28, 2022
It’s awesome. I’m glad my Ram 2500 single cab tradesmen 4x4 hemi is capable of doing everything I need. Kudos to Ram for still making a 3/4 ton 4x4 single cab without all the bells and whistles because people like me like basic things.
Anonymous
Reviewed a 2021 RAM 2500 on Mar 14, 2021
It basically drives itself. Fantastic vehicle and very fuel efficient for a huge diesel.
2021 RAM 2500 Trims
| Trim type | MSRP |
|---|---|
| Big Horn Crew Cab LB 4WD | $46,730 |
| Limited Mega Cab 4WD | $67,540 |
| Laramie Mega Cab 4WD | $55,240 |
| Power Wagon Crew Cab 4WD | $54,740 |
| Tradesman Crew Cab LB 4WD | $42,080 |
| Tradesman Crew Cab 4WD | $41,880 |
| Laramie Crew Cab 4WD | $53,740 |
| Big Horn Crew Cab 4WD | $46,530 |
2021 RAM 2500 Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 RAM 2500 prices has changed over time.
See more price trends









