Used 2021 Mercedes-Benz S-Class for Sale near Illinois
174 results
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 800 currently listed for sale and an average price of $62,114.00, 32.0% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
84.1% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features advanced technology, luxurious interior finishes, and powerful engine options, including a turbocharged inline-six and a twin-turbo V8, providing impressive performance and comfort.
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 800 currently listed for sale and an average price of $62,114.00, 32.0% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
84.1% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features advanced technology, luxurious interior finishes, and powerful engine options, including a turbocharged inline-six and a twin-turbo V8, providing impressive performance and comfort.
Why it stands out
The 2021 Mercedes-Benz S-Class continues to be a benchmark in the full-size luxury sedan segment, marrying performance with unparalleled comfort and cutting-edge technology. This redesigned model integrates a more sophisticated infotainment system and updated powertrains that elevate the driving experience. The S500 and S580 model options cater to different power needs, offering a robust 429 horsepower from the inline-six and a commanding 496 horsepower from the V8, both coupled with a nine-speed automatic transmission.
Noteworthy advancements include a new rear-wheel steering system that improves maneuverability without sacrificing stability, and the introduction of a mild-hybrid system enhancing efficiency. With a beautifully designed cabin featuring ambient lighting and high-quality materials, the S-Class ensures a plush ride for both driver and passengers. Generous cabin space, advanced safety features, and multiple comfort-oriented technologies make this vehicle appealing to buyers who prioritize luxury, performance, and state-of-the-art technology, although its high price point may be a consideration.
Other model years to consider
- Average price: $80,994.00
- Good/great deal percentage: 32.4%
- Total listings: 1,237
- Average price: $65,830.00
- Good/great deal percentage: 32.5%
- User rating: 4.5 / 5
- Total listings: 1,144
- Average price: $26,177.00
- Good/great deal percentage: 31.6%
- User rating: 4.95 / 5
- Total listings: 956
This analysis is based on CarGurus' proprietary market data from May 18, 2026, CarGurus experts' opinions, and generative AI.
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Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
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