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Used 2021 Mercedes-Benz S-Class for Sale near Gainesville, FL

159 results
Gainesville, FL
2022 Mercedes-Benz S-Class S 580 4MATIC AWD Gravity Autos Jacksonville

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

46,308 miles

$64,985

Fair Deal
Jacksonville, FL
68 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Selenite Gray Metallic
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Exclusive Carmine Red/Black
Transmission:
9-Speed Automatic
Mileage:
46,308
Stock number:
112777
VIN:
W1K6G7GB0NA112777

Sponsored

2022 Mercedes-Benz S-Class S 580 4MATIC AWD

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

33,051 miles

$70,889

Good Deal
Certified Pre-Owned
Gainesville, FL
3 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Obsidian Black Metallic
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Exclusive Carmine Red/Black
Transmission:
9-Speed Automatic
Mileage:
33,051
Stock number:
124586
VIN:
W1K6G7GB9NA124586

Sponsored

2020 Mercedes-Benz S-Class S 560 4MATIC Sedan AWD

2020 Mercedes-Benz S-Class

S 560 4MATIC Sedan AWD

63,382 miles

$38,992

Fair Deal
Maitland, FL
78 mi away
Year:
2020
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
463 hp 4L V8
Exterior color:
Red (Ruby Black Metallic)
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
63,382
Stock number:
LA551773
VIN:
W1KUG8GB3LA551773

Sponsored

2022 Mercedes-Benz S-Class S 580 4MATIC AWD

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

33,051 miles

$70,889

Good Deal
Certified Pre-Owned
Gainesville, FL
3 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Obsidian Black Metallic
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Exclusive Carmine Red/Black
Transmission:
9-Speed Automatic
Mileage:
33,051
Stock number:
124586
VIN:
W1K6G7GB9NA124586

Preparing for a close up...

Photos coming soon

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

50,975 miles

$60,440

Great Deal
Certified Pre-Owned
Daytona Beach, FL
81 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Black
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Exclusive Nappa Silver
Transmission:
Automatic
Mileage:
50,975
Stock number:
ZA091681
VIN:
W1K6G7GB1NA091681

Preparing for a close up...

Photos coming soon

2020 Mercedes-Benz S-Class

S 560 Sedan RWD

37,092 miles

$42,646

Good Deal
Daytona Beach, FL
81 mi away
Year:
2020
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
463 hp 4L V8
Exterior color:
Iridium Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black Nappa
Transmission:
Automatic
Mileage:
37,092
Stock number:
PP513279
VIN:
WDDUG8DB8LA513279

Preparing for a close up...

Photos coming soon

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

32,293 miles

$69,518

Good Deal
Certified Pre-Owned
Daytona Beach, FL
81 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Black
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Black Nappa
Transmission:
Automatic
Mileage:
32,293
Stock number:
ZA139295
VIN:
W1K6G7GB7NA139295

Preparing for a close up...

Photos coming soon

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

20,767 miles

$75,997

Fair Deal
Certified Pre-Owned
Orlando, FL
97 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Black
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
MANUFAKTUR Crystal White/Silver Gray Pearl
Transmission:
9-Speed Automatic
Mileage:
20,767
Stock number:
P133588
VIN:
W1K6G7GB3NA133588

Preparing for a close up...

Photos coming soon

2020 Mercedes-Benz S-Class

S 560 4MATIC Sedan AWD

63,382 miles

$38,992

Fair Deal
Maitland, FL
78 mi away
Year:
2020
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
463 hp 4L V8
Exterior color:
Red (Ruby Black Metallic)
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
63,382
Stock number:
LA551773
VIN:
W1KUG8GB3LA551773

Preparing for a close up...

Photos coming soon

2022 Mercedes-Benz S-Class

S 500 4MATIC AWD

38,763 miles

$56,985

Fair Deal
Jacksonville, FL
61 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
429 hp 3L I6
Exterior color:
Rubellite Red
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Gray (Macchiato/Magma Grey)
Transmission:
9-Speed Automatic
Mileage:
38,763
Stock number:
109108
VIN:
W1K6G6DBXNA109108

Preparing for a close up...

Photos coming soon

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

32,293 miles

$69,518

Good Deal
Certified Pre-Owned
Daytona Beach, FL
81 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Black
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Black Nappa
Transmission:
Automatic
Mileage:
32,293
Stock number:
ZA139295
VIN:
W1K6G7GB7NA139295

Sponsored

  1. Home
  2. / Used Cars
  3. / Mercedes-Benz S-Class
  4. / 2021
  5. / Florida
  6. / Gainesville
Overview
Reviews
FAQs

CarGurus Analysis: 2021 Mercedes-Benz S-Class

Picture of 2021 Mercedes-Benz S-Class ## Summary - With 808 currently listed for sale on CarGurus and an **average price of $61,370.00**, 31.9% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars. - **83.4% of 2021 S-Class models on CarGurus are accident free**. - The 2021 Mercedes-Benz S-Class was redesigned to maintain its status as a technological showcase, featuring sophisticated infotainment systems and new powertrains. ## Why it stands out The 2021 Mercedes-Benz S-Class stands out in the luxury sedan segment with its remarkable blend of performance, advanced technology, and unrivaled comfort. This model year features a redesign that introduces more sophisticated infotainment options and improved powertrains, such as the 3.0-liter turbocharged inline-six in the S500 and the powerful 4.0-liter twin-turbo V8 in the S580. Notable updates include a drag coefficient (Cd) of 0.22, enhancing aerodynamics, and innovative features like rear-wheel steering, which improves maneuverability. While the car is not primarily a driver’s car, it balances comfortable riding dynamics with precise steering, making it appeal to buyers looking for both luxury and style. However, some users have mentioned issues with run-flat tires. ## Other model years to consider - **[2022 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2022-Mercedes-Benz-S-Class-c31858)** - Average price: $66,621.00 - Good/great deal percentage: 30.6% - User rating: 4.8 / 5 - Total listings: 1,042 - **[2015 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2015-Mercedes-Benz-S-Class-c24430)** - Average price: $25,902.00 - Good/great deal percentage: 29.3% - User rating: 4.88 / 5 - Total listings: 894 - **[2018 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2018-Mercedes-Benz-S-Class-c27088)** - Average price: $35,246.00 - Good/great deal percentage: 34.0% - User rating: 4.76 / 5 - Total listings: 785 This analysis is based on CarGurus' proprietary market data from February 10, 2026, CarGurus experts' opinions, and generative AI.

5 Overall rating

(7 reviews)
Chris V
5.0
Reviewed a 2021 Mercedes-Benz S-Class on Jun 05, 2024

This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.

Deno P
5.0
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023

This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.

Rob G
5.0
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022

Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.

James B
5.0
Reviewed a 2021 Mercedes-Benz S 580 Sedan 4MATIC on Oct 14, 2024

The car is loaded with luxuries , very stylish at the same time sporty. You get a lot of car for the money and they hold there value. BMW would be close cusin to Mercedes.

Bob D
5.0
Reviewed a 2021 Mercedes-Benz S-Class on Mar 15, 2024

Gently used, beautifully maintained, a real classic. Price was a little too much, otherwise I would have signed the deal.

2021 Mercedes-Benz S-Class FAQs

How much does the 2021 Mercedes-Benz S-Class cost in Gainesville, FL?

The average 2021 Mercedes-Benz S-Class costs about $61,330.83. The average price has decreased by -8.8% since last year. The 157 for sale near Gainesville, FL on CarGurus, range from $27,262 to $150,404 in price.

Is the 2021 Mercedes-Benz S-Class a good car?

CarGurus experts gave the 2021 Mercedes-Benz S-Class an overall rating of 7.5/10 and 2021 Mercedes-Benz S-Class owners have rated the vehicle a 5/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2021 Mercedes-Benz S-Class vehicles in Gainesville, FL have no reported accidents or damage?

120 out of 157 for sale near Gainesville, FL have no reported accidents or damage.

Is the 2021 Mercedes-Benz S-Class safe?

CarGurus experts gave the 2021 Mercedes-Benz S-Class a safety rating of 7/10.

What is the fuel economy of the 2021 Mercedes-Benz S-Class?

Depending on the engine and options, the 2021 Mercedes-Benz S-Class gets between 16 and 64 MPG (or EV battery range).

What fuel types are available?

Gasoline, Hybrid engines are available.

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