Used 2021 Mercedes-Benz S-Class for Sale near Baltimore, MD
188 results
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 180 currently listed for sale near Baltimore, MD and an average price of $60,588.00, 19.4% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars.
83.3% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features advanced technology, luxurious design, and powerful engine options, including a 4.0-liter twin-turbo V8.
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall

Summary
With 180 currently listed for sale near Baltimore, MD and an average price of $60,588.00, 19.4% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars.
83.3% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features advanced technology, luxurious design, and powerful engine options, including a 4.0-liter twin-turbo V8.
Why it stands out
The 2021 Mercedes-Benz S-Class upholds its reputation as a leading luxury sedan, combining opulence and cutting-edge technology. With a redesigned exterior that enhances aerodynamics while maintaining a classic look, the S-Class not only impresses visually but also offers remarkable performance. The introduction of new powertrains, such as the S500's turbocharged inline-six and the S580's V8, provides a thrilling driving experience. Additionally, advanced features such as the updated MBUX infotainment system and a plethora of driver-assist technologies elevate its status among competitors. Owners have shown great satisfaction with its refined handling, with a comfortable ride complemented by luxurious interior materials. Though the price point is higher than some might prefer, those seeking the best in automotive luxury will find the S-Class hard to beat.
Other model years to consider
- Average price: $65,818.00
- Good/great deal percentage: 16.2%
- User rating: 4.8 / 5
- Total listings: 260
- Average price: $24,567.00
- Good/great deal percentage: 19.2%
- User rating: 4.88 / 5
- Total listings: 240
- Average price: $34,707.00
- Good/great deal percentage: 21.0%
- User rating: 4.85 / 5
- Total listings: 176
This analysis is based on CarGurus' proprietary market data from April 7, 2026, CarGurus experts' opinions, and generative AI.
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Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
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